期刊名称:NPJ PRECISION ONCOLOGY
期刊简介(About the journal)
投稿须知(Instructions to Authors)
编辑部信息(Editorial Board)
About the journal
Aims & Scope
npj Precision Oncology is an international, peer-reviewed journal committed to publishing cutting-edge scientific research in all aspects of precision oncology from basic science to translational applications to clinical medicine.
The journal defines precision oncology as cancer diagnosis, prognosis, prevention and/or treatment tailored specifically to the individual patient based on the genetic and/or molecular profile of the patient. High-impact articles that entail relevant studies using panomics, molecular, cellular and/or targeted approaches in the cancer research field are considered for publication. All areas of precision oncology from basic research to clinical applications will be considered.
Featured topics include carcinogenesis, targeted immunotherapy, mechanism-based therapies targeting specific cellular signaling pathways, genetic risk factors, miRNAs, tumor microenvironment, cancer metabolism and cancer stem cells – all in the context of diagnosis/prognosis/therapy, drug resistance mechanisms, reoccurrence, intervention strategies, emerging clinical and translational aspects.
The journal publishes original basic science, translational and clinical research articles, including clinical trials, especially when informed by genetic/molecular profile data.
Instructions to Authors
This section will help you when preparing your manuscript for initial submission and resubmission to npj Precision Oncology. Please ensure that you familiarise yourself with our editorial policies as outlined in our Guide for Authors before submitting your work. An overview of key information on submitting primary research is also available in our brief guide to manuscript submission in PDF format.
For information on our aims and scope, as well as our content types, please refer to the About the journal section.
All manuscripts must be submitted electronically through our online submission system, from which you can upload the cover letter and manuscript files (text, figures and supplementary information, including video) and check on the status of your manuscripts during the review process.
Revised manuscripts should be uploaded through the link provided in the editor's decision letter. Please do not submit revisions as new manuscripts.
The authors must include copies of all related manuscripts with any overlap in authorship that are under consideration or in press elsewhere.
Guide for Authors
View our guide for authors for detailed information on editorial criteria, and how manuscripts are handled by our editors between submission and acceptance for publication.
Manuscripts submitted to npj Precision Oncology do not need to adhere to our formatting requirements at the point of initial submission; formatting requirements only apply at the time of acceptance.
Download Guide for Authors
Editorial Board
Editor-in-Chief
Trever Bivona MD, PhD Prof. of Medicine and Cellular and Molecular Pharmacology University of California, San Francisco CA, USA
Dr. Bivona is a laboratory-based physician scientist at the University of California, San Francisco. He is a cancer biologist who leads a research program focused on signal transduction and cancer genetics and the molecular basis of tumor initiation, progression, and drug resistance. A major area of interest is the function and therapeutic targeting of oncogenic receptor tyrosine kinases and RAS. The goal of this research program is to understand the regulatory principles underlying cancer cell signaling and tumor evolution to improve cancer therapy and patient survival. He is an elected member of the American Society for Clinical Investigation.
Associate Editors
Malak Abedalthagafi, MD, PhD Deputy Director, Assoc. Research Professor King Abdulaziz City of Science and Technology Riyadh, Saudi Arabia
Dr Abedalthagafi is an American board-certified physician-scientist in Clinical Pathology, Anatomical Pathology, Neuropathology, and Molecular Genetics Pathology. She is also the Chair of the Genomics Research Department at King Fahad Medical City. Her research has contributed to advances in molecularly targeted approaches for meningioma and pediatric glioblastoma. Her lab focuses on the intersection between pediatric cancer, familial cancer predisposition syndromes, cancer genomics and therapeutic intervention.
Leila Akkari, PhD Group Leader Netherlands Cancer Institute, Oncode Institute Amsterdam, The Netherlands
Dr. Akkari's main focus of her research is to understand and target the dynamic changes in the tumor microenvironment that are associated with cancer malignancy, with a particular interest in macrophages, a highly plastic and heterogenous immune cell type in solid cancers. Her lab uses a plethora of murine models of cancers to develop and test microenvironment-targeted drugs in a stage-dependent and population-dependent manner.
Pedro Ballester, PhD Group Leader French National Institute of Health and Medical Research Marseille, France
Dr. Ballester heads a team in Machine Learning for Precision Oncology and Drug Design at INSERM. His research interests include the development and application of computational approaches for drug response prediction and pharmaco-omics modeling. Prior to joining INSERM in October 2014, he completed a PhD in Imperial College London and held several postdoctoral fellowships at the University of Oxford, the University of Cambridge and the European Bioinformatics Institute in the UK.
Matthew Gubin, PhD Asst. Professor of Immunology The University of Texas MD Anderson Cancer Center Houston, Texas, USA
The main emphasis of Dr. Gubin's research is to define the antigenic targets of tumor-specific T cells and better understand how T cells recognize and either eliminate cancer or fail to control tumor growth in response to cancer immunotherapy. By combining preclinical genetically engineered mouse models with analysis of human patient samples by high dimensional approaches including single-cell RNA sequencing and mass cytometry by CyTOF, his lab is focused on developing effective combinatorial immunotherapies targeting tumor-specific mutant neoantigens in both primary and metastatic cancer.
Clare Turnbull, MD PhD MA MSc MRCP MFPH Prof. of Genomics, Queen Mary University of London Senior Researcher, Institute of Cancer Research, London London, UK
Dr. Turnbull is a UK academic clinician in the field of cancer susceptibility genomics. She also serves as Honorary Consultant in Clinical Cancer Genetics and in Public Health Medicine for the NHS Trust, and Public Health England, respectively. Her research focuses on identification, characterisation and clinical testing implementation of genomic factors related to cancer susceptibility. She has lead the largest recruitment study of testicular germ cell tumour (TGCT) in the world, and her group has identified the majority of common and rare susceptibility variants for TGCT.
Kris C. Wood, PhD Assoc. Prof. Pharmacology and Cancer Biology Duke University NC, USA
Dr. Wood is a cancer biologist who leads a research program that leverages tools from pharmacology, genomics, and cell signaling to define principles that underlie the design of effective precision anticancer therapeutics. Major research interests include the use of functional genomics approaches to define therapeutic strategies to circumvent resistance and elucidate mechanisms of cell death regulation in cancer. Collectively, these studies are leading to both fundamental new insights into the core survival circuitry operating in defined human tumor subsets as well as novel translational therapeutics.
Seiji Yano, MD, PhD Prof.,Chairman, Cancer Research Institute Kanazawa University Kanazawa, Japan
Dr. Yano is also a translational thoracic medical oncologist and Vice President of Kanazawa University Hospital. Dr. Yano’s research combines laboratory based studies, with translational research and clinical trials of molecular targeted therapy in lung cancer patients. His main research interest is the understanding molecular mechanisms of resistance and tolerance to targeted therapy. Dr. Yano is also in the process of developing novel therapeutics to treat the targeted drug resistant lung cancer in the investigator initiated trials.
Consulting Editor
Javier Carmona, PhD New York, NY
Dr. Carmona started his studies at the University of Navarra and received a degree in Biology from the Autonomous University of Madrid. In 2013, he obtained his Ph.D. after working in Manel Esteller's Cancer Epigenetics and Biology Program in Barcelona. Javier continued his research as a postdoctoral fellow in the group of José Baselga at the Memorial Sloan Kettering Cancer Center in New York, where he studied the mechanisms of resistance to therapy in patients with breast cancer. In 2016 he joined Nature Medicine where is currently a Deputy Editor. Javier has been Consulting Editor on npj Precision Oncology since February 2020.
Founding Editor
Ann M. Bode, PhD Interim Executive Director The Hormel Institute, University of Minnesota MN, USA
Dr. Ann M. Bode is the co-leader of Molecular and Cellular Biology research sections at The Hormel Institute, University of Minnesota. Previously, Dr. Bode ran a research program specializing in biomarker discovery and research focusing on the role of reactive oxygen species and antioxidants in chronic diseases, including cancer and diabetes. Her current research is focused on molecular and cellular mechanisms of cancer development and the identification of biomarkers that could determine whether a certain drug will be effective for preventing or treating cancer. She is a member of the Masonic Cancer Center, American Society of Clinical Oncology, American Association for the Advancement of Science and American Association for Cancer Research.
Editorial Board Members
Carlos L. Arteaga, MD Vanderbilt-Ingram Cancer Center, Vanderbilt University Nashville, Tennessee, USA
Aditya Bardia, MD Harvard Medical School Boston, Massachusetts, USA
Andrew Biankin, PhD University of Glasgow Glasgow, Scotland
Powel H. Brown, MD, PhD The University of Texas MD Anderson Cancer Center Houston, Texas, USA
Prof. Carlos Caldas Cancer Research UK Cambridge Institute Cambridge, UK
Webster K. Cavenee, PhD Ludwig Institute for Cancer Research La Jolla, California, USA
Ilana Chefetz Menaker, PhD The Hormel Institute, University of Minnesota Austin, Minnesota, USA
Robert B. Diasio, MD Mayo Clinic Rochester, Minnesota, USA
Dan Dixon, PhD University of Kansas Cancer Center Kansas City, Kansas, USA
Ernie Hawk, MD The University of Texas MD Anderson Cancer Center Houston, Texas, USA
Luke H. Hoeppner, PhD The Hormel Institute, University of Minnesota Austin, Minnesota, USA
Nada Jabado, MD, PhD McGill University Health Centre Research Institute Montreal, Quebec, Canada
Paul J. Limburg, MD Mayo Clinic Rochester, Minnesota, USA
Scott M. Lippman, MD UC San Diego School of Medicine La Jolla, California, USA
Rebecca J. Morris, PhD The Hormel Institute, University of Minnesota Austin, Minnesota, USA
Nicholas Navin, MD The University of Texas MD Anderson Cancer Center Houston, Texas, USA
Emanuel F. Petricoin Ph.D George Mason University Manassas, Virginia USA
Padmannee Sharma, MD, PhD The University of Texas MD Anderson Cancer Center Houston, Texas, USA
Dong Moon Shin, MD, FACP Emory University School of Medicine Atlanta, Georgia, USA
Sanjay K. Srivastava, PhD Texas Tech University Health Sciences Center Amarillo, Texas, USA
Young-Joon Surh, PhD Molecular Medicine and Biopharmaceutical Sciences, Seoul National University Seoul, Korea
Eva Szabo, MD National Cancer Institute Bethesda, Maryland, USA
Josep Tabernero, MD, PhD Vall d'Hebron Institute of Oncology Barcelona, Spain
Hongyang Wang, MD, PhD Chinese Academy of Sciences Shanghai, China
Douglas Yee, MD Masonic Cancer Center, University of Minnesota Minneapolis, Minnesota, USA
Yi Xin Zeng, PhD Sun Yat-Sen University Guangzhou, China
Nature Research
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