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期刊名称：ACS MEDICINAL CHEMISTRY LETTERS ISSN： 1948-5875 出版频率： Monthly 出版社： AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, USA, DC, 20036   出版社网址： http://pubs.acs.org/ 期刊网址： http://pubs.acs.org/journal/amclct 影响因子： 4.345 主题范畴： CHEMISTRY, MEDICINAL 期刊简介(About the journal)    投稿须知(Instructions to Authors)    编辑部信息(Editorial Board)    About the journal ACS Medicinal Chemistry Letters publishes brief communications on experimental or theoretical results of exceptional timeliness in all aspects of medicinal chemistry (pure and applied) and its extension into pharmacology. The journal publishes studies that range from compound design to optimization, biological evaluation, drug delivery, and pharmacology. Specific areas include, but are not limited to: 1.Identification, synthesis, and optimization of lead biologically active compounds and drugs 2.Biological characterization of new chemical entities in the context of drug discovery 3.Computational, cheminformatics, and structural studies for the identification or SAR analysis of bioactive molecules, ligands and their targets, etc. 4.Novel and improved methodologies, including radiation biochemistry, with broad application to medicinal chemistry 5.Discovery technologies for biologically active compounds from both synthetic and natural (plant and other) sources 6.Pharmacokinetic/pharmacodynamic studies that address mechanisms underlying drug disposition and response 7.Pharmacogenetic and pharmacogenomic studies used to enhance drug design and the translation of medicinal chemistry into the clinic 8.Mechanistic drug metabolism and regulation of metabolic enzyme gene expression   Manuscript Categories ACS Medicinal Chemistry Letters publishes: Letters - short, peer-reviewed reports of original research focused on an individual finding significant to a broad medicinal chemistry field Technology Notes - peer-reviewed Notes that describe new "toolbox" innovations encompassing a myriad of technologies (high throughput/high content screening, robotics, structure-based drug design, fragment-based drug design, combinatorial chemistry/parallel synthesis, etc.) that simultaneously facilitate and partially define modern medicinal chemistry The journal will also include sections describing significant new patents and drug discovery tools. Instructions to Authors amclct_authguide.pdf Editorial Board Editor-in-Chief Dennis C. Liotta Department of Chemistry Emory University Cherry Logan Emerson Hall Atlanta, GA 30322 Phone: (404) 727-6602 E-mail: dliotta@emory.edu   Associate Editors Bruce E. Maryanoff The Scripps Research Institute   Peter Wipf University of Pittsburgh   Editorial Advisory Board Jeffrey Aubé University of Kansas   Anthony G. M. Barrett Imperial College London   Annette Beck-Sickinger University of Leipzig   Brian S. J. Blagg University of Kansas   Maurizio Botta Siena University   Nick I. Carruthers Johnson & Johnson   Pat N. Confalone Dupont   P. Jeffrey Conn Vanderbilt University   Benjamin F. Cravatt The Scripps Research Institute   Ke Ding Chinese Academy of Sciences   Gunda I. Georg University of Minnesota   Arun K. Ghosh Purdue University   William J. Greenlee Merck Research Laboratories   Yvan Guindon Institut de recherches cliniques de Montréal   Stephen Hanessian Université de Montréal University of California, Irvine   Amy Hauck Newman NIH   Donna M. Huryn University Pennsylvania   Kenneth Jacobson National Institute of Diabetes & Digestive & Kidney Diseases   John A. Katzenellenbogen University of Illinois, Urbana-Champaign   Povl Krogsgaard-Larsen University of Copenhagen   Derek Lowe Vertex Pharmaceuticals   John E. Macor Bristol-Myers Squibb   Bryan L. Roth University of North Carolina   Jing-Kang Shen Chinese Academy of Sciences   Richard B. Silverman Northwestern University   Mikiko Sodeoka RIKEN, The Institute of Physical and Chemical Research   Kiyoshi Tomioka Kyoto University   Kristof Van Emelen Tibotec Research and Development   Shaomeng Wang University of Michigan   Ann E. Weber Merck Research Laboratories   Jeff Zablocki Gilead Sciences, Inc.   Zhong-Yin Zhang Indiana University School of Medicine   Ming-Ming Zhou Mount Sinai School of Medicine