期刊名称：BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
 期刊简介(About the journal)
投稿须知(Instructions to Authors)
编辑部信息(Editorial Board)
About the journal
Aims and Scope
Basic & Clinical Pharmacology and Toxicology is an independent journal, publishing original scientific research in all fields of toxicology, basic and clinical pharmacology. This includes experimental animal pharmacology and toxicology and molecular (-genetic), biochemical and cellular pharmacology and toxicology. It also includes all aspects of clinical pharmacology: pharmacokinetics, pharmacodynamics, therapeutic drug monitoring, drug/drug interactions, pharmacogenetics/-genomics, pharmacoepidemiology, pharmacovigilance, pharmacoeconomics, randomized controlled clinical trials and rational pharmacotherapy. For all compounds used in the studies, the chemical constitution and composition should be known, also for natural compounds.
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Instructions to Authors
NOTICE TO CONTRIBUTORS
Aim and Scope
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY is an independent journal, publishing original scientific research in all fields of toxicology, basic and clinical pharmacology. This includes experimental animal pharmacology and toxicology and molecular (-genetic), biochemical and cellular pharmacology and toxicology. It also includes all aspects of clinical pharmacology: pharmacokinetics, pharmacodynamics, therapeutic drug monitoring, drug/drug interactions, pharmacogenetics/-genomics, pharmacoepidemiology, pharmacovigilance, pharmacoeconomics, randomized controlled clinical trials and rational pharmacotherapy. For all compounds used in the studies, the chemical constitution and composition should be known, also for natural compounds.
Submission of manuscripts
Manuscripts written in the English language should be submitted online to http://www.manuscriptmanager.com/bcpt.
All submitted manuscripts must be accompanied by either a completed Exclusive Licence Form or a completed Online Open Exclusive Licence Form.
Online Open
OnlineOpen is a pay-to-publish service from Blackwell that offers authors whose papers are accepted for publication the opportunity to pay up-front for their manuscript to become open access (i.e. free for all to view and download) via the BCPT's online content platform. Each OnlineOpen article will be subject to a one-off fee of $3000 to be met by or on behalf of the Author in advance of publication. Upon online publication, the article (both full-text and PDF versions) will be available to all for viewing and download free of charge. The print version of the article will also be branded as OnlineOpen and will draw attention to the fact that the paper can be downloaded for free via BCPT's online content platform.
If you do not wish your paper to be OnlineOpen, you are required to complete the standard Exclusive Licence Form. Please note that only one form should be completed. Papers cannot be published until one of the two completed forms has been received. The author's choice of publication form will not influence the reviewing process.
Manuscripts must be accompanied by a covering letter, which should include information about prior or duplicate publication or submission elsewhere of any part of the work. It should also include a statement that the manuscript has been read and approved by all authors. In addition, the submission letter should contain any other information that may be helpful to the Editor.
Manuscripts not following the present instructions are returned without editorial evaluation. Authors are advised to check the consistency between the present instructions and their manuscript as to style and language, and to consult a current issue of the journal for general and specific manners of presentation.
Authors submitting a paper do so on the understanding that the results have not been published before, that the manuscript is not being considered for publication elsewhere and that it has been read and approved by all authors. Authors submitting a manuscript do so on the understanding that the exclusive licence to publish the article and illustrative material therein in all forms of media shall be granted to BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY if and when a manuscript is accepted for publication. The work should not be published elsewhere in any language without the written consent of the journal. The articles published in this journal are protected by copyright law which covers translation rights and the exclusive right to reproduce and distribute all articles printed in the journal. No material published in the journal may be stored on microfilm or videocasettes or in electronic databases and the like without the written permission of the journal.
Word 2007
Will authors please note that Word 2007 is not yet compatible with journal production systems. Unfortunately, the journal cannot accept Microsoft Word 2007 documents until such time as a stable production version is released. Please use Word's 'Save As' option therefore to save your document as an older (.doc) file type.
Liability
No responsibility is assumed by the journal for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions or ideas contained in the material published herein.
Ethical guidelines
Studies involving human beings must be conducted in accordance with the Declaration of Helsinki and guidelines on Good Clinical Practice.
For the humane use and care of experimental animals, internationally accepted principles must be observed. The ethical standards in Directive 86/609/EEC, 'European Convention for the Protection of Vertebrate Animals Used for Experimental and other Scientific Purposes', 1986, and the 'Guiding Principles in the Use of Animals in Toxicology', adopted by the Society of Toxicology in 1989, for the acceptable use of experimental animals, must be adhered to. In general, manuscripts in which animals are used without reasonable respect to their lives and sufferings will not be accepted.
Live experimental animals should only be used, if similar results can not be obtained by alternative methods, e.g. in vitro methods.
Conflict of interest and sources of funding
The politics of BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY regarding conflict of interest and sources of funding complies with the 'Uniform Requirements for Manuscripts Submitted to Biomedical Journals' (http://www.icmje.org/). Thus, a conflict of interest exists if an author, reviewer or an editor handling any given manuscript has ties that could influence his or her judgement in an inappropriate manner. This could typically be financial ties with industry either directly or indirectly via family in the form of research funding, employment, consultancies, stock ownership, honoraria or expert testimony. Other sources of conflict of interest could be personal relationships, academic competition and intellectual passion. Authors submitting a manuscript to BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY are entitled to disclose any conflict of interest, and in the event the manuscript will be published, these will be published as well. This includes disclosure of all sources of funding. The Editor and MiniReview Editors will abstain from participation in the peer review process and editorial handling of a manuscript if a conflict of interest exists, and the same applies to the reviewers.
Organization of manuscripts
Manuscripts should be submitted in the English language (see above). They should be double-spaced and with a wide margin. Pages should be numbered consecutively, beginning with the title page, which should contain a concise title, institution(s) or laboratory(ies) where the work was done, names of all authors with first names spelled out, and an abbreviated form of the title (running title). Full mailing address in English for the corresponding author should also be given including telefax number and e-mail address.
Page 2 should contain an abstract of up to 250 words. The abstract should contain a summary of what was done, the results obtained, and valid conclusions drawn therefrom. The following pages should contain Introduction and background (long historical introductions should be avoided, a reference to bibliographies in handbooks or the like will suffice), followed by Materials and Methods, Results, Discussion which should incorporate the conclusion(s) drawn from the study, Acknowledgements, References, numbered tables with legends, and illustrations or graphs in high quality with legends on separate sheets.
Abbreviations in tables and figures should be explained in the legends. Text and footnotes must contain all the information necessary to understand and interpret the table without reference to the text.
Illustrations must be clear enough to permit readable reproduction. Symbols should be large enough to be readable also after reduction of the illustration.
The experimental results should on the whole be published only in the form of graphs or tables, which must contain all the information necessary to understand the table or illustration without reference to the text.
Illustrations
Tables. Each table should have a brief, specific, descriptive title, giving sufficient explanation to make the data intelligible without reference to the text. Number all tables and cite in numerical order in the text, using Arabic numerals.
Preparation of figures. Cite figures in the text in numerical order using Arabic numerals. For peer-review submission, follow the online uploading instructions. Please save vector graphics (e.g. line artwork) in Encapsulated Postscript Format (EPS) and bitmap files (e.g. half-tones) in Tagged Image File Format (TIFF). Ideally, vector graphics that have been saved in metafile (.WMF) or pict (.PCT) format should be embedded within the body of the text file. Detailed information on our digital illustration standards is available at http://www.blackwellpublishing.com/authors/digill.asp. Always send a hard copy of digitally supplied figures to the Central Editorial Office (details above).
Figure sizing for accepted manuscripts. For the print publication, lay out figures as compactly as is consistent with conveying the relevant data. Figures will be sized to fit the smallest possible space, but in order to prevent radical changes in figure content, prepare the figures in one of two sizes: 8.0 cm (1-column width) or, if necessary, 11.5 cm (11/2 column width). These instructions do not apply to figures submitted for online review and prepublication.
Figure legends. All legends must begin with a short descriptive sentence that sums up the intent and content of the data contained in the figure. This sentence should be in boldfont. A more detailed explanation of the data contained in the figure and/or its parts should follow. The detailed description should be in Roman type (ie, not in boldfont).
Colour charges. Colour charges apply to all articles printed in Basic & Clinical Pharmacology and Toxicology. Therefore, please note that if there is colour artwork in your manuscript when accepted for publication, which you would like to appear in print, Blackwell Publishing require you to complete and return a colour work agreement form before your paper can be published. This form can be downloaded as PDF from the internet. (Please note that we are pleased to provide colour online only free of charge. If you would like to take advantage of this, please ensure that your image is suitable for both colour and black/white publication. For example, please do not refer to the 'red dots' or 'blue lines', as these will NOT be apparent in the print version.) The Web address for the form is: http://www.blackwellpublishing.com/pdf/SN_Sub2000_F_CoW.pdf. Once completed, please return the form to the Production Editor. Please correspond with the Editor-in-chief on acceptance of the manuscript.
References
As of 1 January 2007, references must be cited according to the Vancouver system (http://www.icmje.org).
Basic & Clinical Pharmacology & Toxicology deviates from icmje in the following respects:
- No full stop after the abbreviated name of the journal
- As journals paginate consecutively, issue number is not used; only volume and page number.
Journal names should be abbreviated according to the system used in Index Medicus (Pubmed Service "Journals Database").
Number the references consecutively in the order they appear for the first time in the text. References that are cited in table or figure texts should be numbered in accordance with the first appearance of the table or figure in question. References in the text must be cited with the appropriate number in square bracket. In case of more than one reference in one square bracket, the numbers must be separated by a comma, e.g. [3, 4, 8]; In case of more than two consecutive reference numbers, use hyphen, e.g. [6-9];
Avoid abstracts and meeting proceedings as references; unpublished observations and personal communications must not be used as references. Accepted manuscripts that have not yet been published may appear in the reference list. Indicate journal name and year in question followed by "in press" in brackets. Articles published online are identified by their DOI (Digital Object Identifier System) reference (http://dx.doi.org/). Electronic material is cited like other literature.
In general, references must be written as follows
Surname followed by initial(s) without comma or full stop; then comma before the next author's surname followed by his/her initial(s): Larsen JT, Brøsen K.
If there are more than six authors, et al after the sixth author's initial(s) should be added:
Smith PJ, Byron AM, Jones E, Andersson C, Tucker AD, Rowland P et al.
Put a full stop after the last author's initials (or after et al), and before the article/monography title etc.
The title should be written with initial capital while all other words are in small letters, unless it is a matter of nationalities (in a Swedish population) or names of e.g. commissions and the like. As a rule, continue with small letters after colon. Do not include subtitle.
The journal name should be written with ordinary font (no italics); do not put full stops between the individual parts of the abbreviation or between the journal name and year: Basic Clin Pharmacol Toxicol 2005.
Year, volume number and pages should be written without space.
Put a semicolon between year and volume number and colon between volume number and page number: BMJ 2004;329:1233-6.
Examples of correctly written references
Journal article
Brøsen K, Skjelbo E, Rasmussen BB, Poulsen HE, Loft S. Fluvoxamine is a potent inhibitor of cytochrome P4501A2. Biochem Pharmacol 1993;45:1211-4.
Rasmussen SG, Gether U. Purification and fluorescent labelling of the human serotonin transporter Biochemistry 2005;44:3494-505.
Book chapter
Zanger UM, Eichelbaum M. CYP2D6. In: Levy RH, Thummel KE, Trager WF, Hansten PD, Eichelbaum M (eds). Metabolic Drug Interactions. Lippincott Williams & Willis Philadelphia PA 2002;87-94.
DOI reference
Masmanian SK, Thon-That H, Schneewind O. Sortase catalysed anchoring of surface proteins to the cell wall of Stapylococcus aureus. Mol Microbiol 2001;40:1049-1057.
Doi: 10.1046/j. 1365-2958.2001.02411.x
Internet reference
http://www.imm.ki.se/CYPalleles /March 2006
We recommend the use of a tool such as EndNote or Reference Manager for reference management and formatting. EndNote reference styles can be searched for here: http://www.endnote.com/support/enstyles.asp. Reference Manager reference styles can be searched for here: http://www.refman.com/support/rmstyles.asp.
Language
The manuscript should be written in a concise and clear British English language. Some linguistic in-house correction is performed, however, a manuscript may be returned to the authors for major linguistic revision and rewriting. The authors have the full responsibility for the English language and the style of the manuscript. The manuscript will be edited according to the style of the journal, and the proofs must be read carefully by the author.
Nomenclature
The international nomenclature should be used. Chemical formulae should as far as possible be written on one line. If proprietary names are used, the chemical constitution or, if this is not known, the outline of the preparation must appear clearly in the text. When available, INN-names should be used.
Only officially accepted abbreviations and abbreviations of long chemical names etc. should be used. Unnecessary abbreviations impede the reading of a paper; therefore the number of abbreviations should be kept at an absolute minimum. Necessary abbreviations should be used with consistency and defined at first mention. Abbreviations should not be used in the title of the paper and in the running title.
Page Charges
Authors will be charged GBP 150 for each page in the final published version exceeding 6 printed pages, although for 'Short Communications' GBP 150 for each page exceeding 2 printed pages. Page charge does not apply to MiniReviews. As a rule of thumb, an average text page in the printed issue (without figures and tables) is approximately 900 words.
Short communications
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY will accept 'Short Communications' for rapid publication of important experimental results and short preliminary results. The length of the manuscript should not exceed 2 printed pages including title, general text, presentation of experimental results without headings, either table or figure, and references. The general rules for manuscripts published in BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY should be followed. No abstract is necessary. Authors will be charged for pages in excess of 2 printed pages, according to the above Page charge paragraph.
MiniReviews
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY accepts invited MiniReviews, which will be peer-reviewed and should conform to the form and style of the journal. MiniReviews should be up to 8 printed pages including a maximum of 50 references.
Letters to the Editor and Annotations & Reflections
Letters to the Editor may contain essential corrections and comments to articles published in the journal. Letters to the Editor will be published without delay after acceptance. Annotations & Reflections concerning important developments within the publication scope of the journal will be accepted by the Editor. Annotations & Reflections should not exceed 6 printed pages.
Supplements
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY will publish supplements, consisting of e.g. monographs, abstracts or papers from a congress or a symposium, articles or a series of articles or a doctorate thesis. The publication of the supplement should be approved by the journal, and the authors or organizers will be responsible for all production and mailing costs, unless otherwise agreed. After approval, the supplements are not subject to revision by the Editorial Office. The quality of language must meet the standards maintained by the journal, and all the above-mentioned instructions should be followed. Supplements are delivered free of charge to the subscribers of the journal.
Further information and cost estimates may be obtained from the Editorial Office.
Offprints
The corresponding author will be provided with a free pdf-file of the article.
Announcements
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY will accept for publication announcements of interest to pharmacologists and toxicologists (the readers), such as notices of congresses, society meetings, symposia, awards, or other matters.
Note to NIH Grantees
Pursuant to NIH mandate, Wiley-Blackwell will post the accepted version of contributions authored by NIH grant-holders to PubMed Central upon acceptance. This accepted version will be made publicly available 12 months after publication. For further information, see www.wiley.com/go/nihmandate.
Editorial Board
Editorial Information
Editor:
Kim Brosen, Odense, Denmark
Associate Editors:
Jens Lykkesfeldt, Copenhagen, Denmark
Ulf Simonsen, Aarhus, Denmark
Editorial Manager:
Henrik Horneberg, Odense, Denmark
Editorial Assistant:
Tina Ludvig-Nymark, Odense, Denmark
Editorial Office:
Basic & Clinical Pharmacology & Toxicology
University of Southern Denmark
Clinical Pharmacology
Winslowparken 19, 2nd floor
DK-5000 Odense C
Denmark
Tel. +45-6550-4237
Fax +45-6591-6089
hhorneberg@health.sdu.dk
Executive Committee:
Ian Ahnfelt-Rønne, Copenhagen, Denmark
Hans Bräuner-Osborne, Copenhagen, Denmark
Ulrik Gether, Copenhagen, Denmark
Jesper Bo Nielsen, Odense, Denmark
Helle Northeved, Copenhagen, Denmark
Thomas Kongstad Petersen, Copenhagen, Denmark
Mini Reviews:
Jesper Hallas, Odense, Denmark
Eeva Moilanen, Tampere, Finland
Lisbeth Ehlert Knudsen, Copenhagen, Denmark
American Field Editor:
William Campbell, USA
Editorial Advisers:
Andersson, Karl-Erik, Lund, Sweden
Autrup, Herman, Aarhus, Denmark
Benitez, Julio, Badajoz, Spain
Bond, James, Research Triangle Park, NC, USA
Chlopicki, Stefan, Krakow, Poland
Corcoran, George B, Detroit, MI, USA
Du, Guan Hua, Beijing, P.R. China
Dusinska, Maria, Kjeller, Norway
Garland, Chris, Bath, UK
Huupponen, Risto, Turku, Finland
Javitch, Jonathan A, New York, NY, USA
Karlsson, Mats, Uppsala, Sweden
Kodavanti, Prasada Rao S., Research Triangle Park, NC, USA
Korpi, Esa, Helsinki, Finland
Kroemer, Heyo, Greifswald, Germany
Loft, Steffen, Copenhagen, Denmark
Moore, Nicolas, Bordeaux, France
Mulvany, Michael J, Aarhus, Denmark
Osnes, Jan-Bjørn, Oslo, Norway
Parnham, Michael J, Zagreb, Croatia
Rørth, Mikael, Copenhagen, Denmark
Spina, Eduardo, Messina, Italy
Stürmer, Til, Chapel Hill, NC, USA
Sugiyama, Yuichi, Tokyo, Japan
Thürmann, Petra, Wuppertal, Germany
Vanhoutte, Paul M., Hong Kong
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