1. Original Research Articles. An abstract, Introduction, Materials and Methods, Results, and Discussion sections are required. The literature review should be succinct. There are no restrictions on the number of pages or figures.
2. Review Articles in which a specific field is reviewed through an exhaustive literature survey. An abstract is required. A Materials and Methods section and a Results section are not required. There are no restrictions on the number of pages or figures. Review articles are usually invited, but submitted review articles will be considered.
All manuscripts, whether invited or regular submissions, are peer reviewed.
Manuscripts
General instructions. For the review process, all manuscripts should be submitted as e-mail enclosures to the editor or appropriate associate editor. The manuscript and figures should be no larger than one megabyte and can be sent as zipped or sent in a condensed file format. The text file (Microsoft Word or other) is usually much smaller than figure files which should be sent as JPG files no larger than 50 kbytes. Since images viewed on a computer screen are 72 ppi, the size of the images need to be formatted to fit on a 14 inch computer screen. The author also needs to submit the names, addresses, and e-mail addresses of 5 scientists who can impartially review their manuscript.
Revised manuscripts that are being submitted after revision (send two hard copy sets) should be typed double-spaced throughout on one side of bond or heavy bodied paper 8 1/2" X 11" (22 X 28 cm) with a 1" (2.5 cm) margin on all sides. A digital copy of the manuscript should also be included. The manuscript should be submitted in a word processing format (Microsoft Word 6.0 or later) and the figures should be sent as high resolution Tiff files in resolutions as indicated in "Disk Submission Instructions." On a separate sheet of paper, the author should indicate how he/she has addressed all the changes that have been requested and which have been yellow highlighted on one of the two paper hard copies.
Number all manuscript pages consecutively, beginning with the title page. The manuscript should have a uniform style and be submitted in the correct journal format, carefully proofed for grammar, spelling, and punctuation. It should consist of subdivisions in the following sequence.
- Title page
- Abstract
- Text
- Acknowledgments
- References
- Footnotes
- Tables
- Figure legends
Note: Start each subdivision on a new page.
Title Page. The first page of the manuscript should include:
- Title of paper
- Full name of author(s)
- Institutional affiliation and complete mailing address
- A running title not to exceed 45 letters and spaces
- Individual, address, and telephone number to whom correspondence concerning the manuscript should be sent
Key Words. Key words (not used in the title) should be included and should not exceed 85 characters and spaces.
Abstract. Submit an abstract of 250 words or less that will serve in lieu of a concluding summary. The abstract must be written in complete sentences and succinctly state the objectives, experimental design of the paper, principal observations, and conclusions; and be intelligible without reference to the rest of the paper.
Text. The text should be presented in the following order: INTRODUCTION; MATERIALS AND METHODS; RESULTS; DISCUSSION.
References.
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In the text, references to the literature should be made by author's name followed by year of publication arranged by alphabetical order first, then by year of publication:
. . . studies by Briggs (1975) reveal . . .
. . . earlier reports (Anderson and Stevens, 1977; Mahler, 1976; 1977), . . .
When references are made to more than one paper by the same author, published in the same year, they are to be designated in the text as (Hinck et al., 1994a, b) and in the reference list as follows:
Hinck L, Nathke I, Papkoff J, Nelson W. 1994a. Dynamics of cadherin/catenin complex formation: novel protein interactions and pathways of complex assembly. J Cell Biol 125:1327-1340.
Hinck L, Nelson WJ, Papkoff J. 1994b. Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing beta-catenin binding to the cell adhesion protein cadherin. J Cell Biol 124: 729-741.
References are to be arranged alphabetically in the following style: Author's name (or names), year of publication, complete article title, abbreviated journal title, volume, and inclusive pages as follows:
Journal article
King VM, Armstrong DM, Apps R, Trott JR. 1998. Numerical aspects of pontine, lateral reticular, and inferior olivary projections to two paravermal cortical zones of the cat cerebellum. J Comp Neurol 390:537-551.
Book
Voet D, Voet JG. 1990. Biochemistry. New York: John Wiley & Sons. 1223 p.
Book chapter
Gilmor ML, Rouse ST, Heilman CJ, Nash NR, Levey AI. 1998. Receptor fusion proteins and analysis. In: Receptor Localization. Ariano MA, editor. Wiley-Liss, New York, pp 75-90.
Footnotes Number footnotes to the text with consecutive arabic numerals. The corresponding reference numbers must be clearly indicated in the text. Additional references to the identical footnote must be numbered with the next consecutive number; for example:
1Material used for this experiment was
2Provided by . . .
Type footnotes to a table directly beneath the table and number them 1, 2, 3, etc. They must not be numbered in sequence with text footnotes.
Tables All tables must be cited in the text and have titles. Number them consecutively with arabic numerals. Table titles should be complete but brief. Information other than that defining the data should be presented as footnotes. Since tabular material is expensive to reproduce, it should be simple and uncomplicated, with as few vertical and horizontal rules as possible.
Illustrations
To achieve greatest fidelity and rendition of detail, it is preferable that the printer work directly from original drawings or high-quality photographic prints (but not photocopies made on an office duplicating machine). All illustrations must be submitted in complete and finished form with adequate labeling.
Authors are encouraged to submit color illustrations when the color conveys essential scientific information. All color figures will be reproduced in full color in the online edition of the journal at no cost to authors. Color illustration is available at no cost to the author in the print edition of the journal ONLY after consultation between author and Editor. Additional pages of color reproduction in the print edition of the journal will be subsidized by the publisher, reducing author costs to $500 per page. For best reproduction, bright, clear colors should be used. Dark colors against a dark background do not reproduce well; please place your color images against a white background wherever possible. Please contact Carol Hagan at 1-800-238-3814 ext. 622 or haganc@cadmus.com for further information.
Black-and-white prints. Prints should be on white, glossy photographic paper. Micrographs and other figures should be designed for reproduction at full text width (6 3/4 inches) and a maximum of 9 inches high, or at single column width (3 5/16 inches) and a maximum of 9 inches high. Place a circled number ("transfer lettering") in the bottom left corner of the illustration. Magnification may be indicated by a micron bar or in the legend. If more than one illustration is mounted as a plate, number and letter them left to right, top to bottom.
Send two sets of manuscripts and illustrations to one of the following editors:
Dr. George Ruben
Editor-in-Chief
Microscopy Research and Technique
Department of Biology
Dartmouth College
Hanover, New Hampshire 03756
Phone (603) 448-1726; Fax (603) 448-0174
E-Mail: George.C.Ruben@Dartmouth.edu
Dr. George Perry
Biological Sciences Editor
Microscopy Research and Technique
Professor of Pathology and Neurosciences
Case Western Reserve University
Institute of Pathology
2085 Adelbert Road
Cleveland, Ohio 44106
Phone (216) 368-2488; Fax (216) 368-8964
E-Mail: gxp7@po.cwru.edu
Dr. Kenneth H. Downing
High Resolution Electron Microscopy Editor
Microscopy Research and Technique
Life Sciences Division
112 Donner Laboratory
Lawrence Berkeley National Laboratory
Berkeley, California 94720
Phone (510) 486-5941; Fax (510) 486-6488
E-Mail: khdowning@lbl.gov
Dr. Alberto Diaspro
Light Microscopy Sciences Editor
Microscopy Research and Technique
INFM-Department of Physics
University of Genoa
Via Dodecaneso 33
16146 Genoa, Italy
Phone +39-0103536426/480; Fax 01034218
E-Mail: diaspro@fisica.unige.it
Disk Submission Instructions
Please return your final, revised manuscript on disk as well as hard copy.
The hard copy must match the disk.
The Journal strongly encourages authors to deliver the final, revised version of their accepted manuscripts (text, tables, and, if possible, illustrations) on disk. Given the near-universal use of computer word-processing for manuscript preparation, we anticipate that providing a disk will be convenient for you, and it carries the added advantages of maintaining the integrity of your keystrokes and expediting typesetting. Please return the disk submission slip below with your manuscript and labeled disk(s).
Guidelines for Electronic Submission
Text
Storage medium. 3-1/2" high-density disk in IBM MS-DOS, Windows, or Macintosh format.
Software and format. Microsoft Word 6.0 is preferred, although manuscripts prepared with any other microcomputer word processor are acceptable. Refrain from complex formatting; the Publisher will style your manuscript according to the Journal design specifications. Do not use desktop publishing software such as Aldus PageMaker or Quark XPress. If you prepared your manuscript with one of these programs, export the text to a word processing format. Please make sure your word processing program's "fast save" feature is turned off. Please do not deliver files that contain hidden text: for example, do not use your word processor's automated features to create footnotes or reference lists.
File names. Submit the text and tables of each manuscript as a single file. Name each file with your last name (up to eight letters). Text files should be given the three-letter extension that identifies the file format. Macintosh users should maintain the MS-DOS "eight dot three" file-naming convention.
Labels. Label all disks with your name, the file name, and the word processing program and version used.
Illustrations
All print reproduction requires files for full color images to be in a CMYK color space. If possible, ICC or ColorSync profiles of your output device should accompany all digital image submissions.
Storage medium. Submit as separate files from text files, on separate disks or cartridges. If feasible, full color files should be submitted on separate disks from other image files. 3-1/2" high-density disks, CD, Iomega Zip, and 5 1/4" 44- or 88-MB SyQuest cartridges can be submitted. At authors' request, cartridges and disks will be returned after publication.
Software and format. All illustration files should be in TIFF or EPS (with preview) formats. Do not submit native application formats.
Resolution. Journal quality reproduction will require greyscale and color files at resolutions yielding approximately 300 ppi. Bitmapped line art should be submitted at resolutions yielding 600-1200 ppi. These resolutions refer to the output size of the file; if you anticipate that your images will be enlarged or reduced, resolutions should be adjusted accordingly.
File names. Illustration files should be given the 2- or 3-letter extension that identifies the file format used (i.e., .tif, .eps).
Labels. Label all disks and cartridges with your name, the file names, formats, and compression schemes (if any) used. Hard copy output must accompany all files.
Print and return with labeled diskette(s)
Corresponding author's name:
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E-mail address:
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Manuscript number:
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Program(s) & version(s) used:
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Signature: __________________________________________
Date: _____________
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