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期刊名称：MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING ISSN： 0140-0118 版本： SCI-CDE 出版频率： Monthly 出版社： SPRINGER HEIDELBERG, TIERGARTENSTRASSE 17, HEIDELBERG, GERMANY, D-69121   出版社网址： http://www.springer.com/?SGWID=8-102-0-0-0 期刊网址： http://www.springer.com/biomed/human+physiology/journal/11517 影响因子： 2.602 主题范畴： COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;    ENGINEERING, BIOMEDICAL;    Mathematical & Computational Biology;    MEDICAL INFORMATICS 期刊简介(About the journal)    投稿须知(Instructions to Authors)    编辑部信息(Editorial Board)    About the journal Founded in 1963, Medical & Biological Engineering & Computing (MBEC) continues to serve the biomedical engineering community, covering the entire spectrum of biomedical and clinical engineering. The journal presents exciting and vital experimental and theoretical developments in biomedical science and technology, and reports on advances in computer-based methodologies in these multidisciplinary subjects. The journal also incorporates new and evolving technologies including cellular engineering and molecular imaging. MBEC publishes original research articles as well as reviews and technical notes. Its Rapid Communications category focuses on material of immediate value to the readership, while the Controversies section provides a forum to exchange views on selected issues, stimulating a vigorous and informed debate in this exciting and high profile field. MBEC is an official journal of the International Federation of Medical and Biological Engineering (IFMBE). Abstracted/Indexed in:  Academic OneFile, Academic Search, AGRICOLA, Allied and Complementary Medicine Database (AMED), Biological Abstracts, BIOSIS, Biotechnology Abstracts, Business Source, Compendex, Computer Science Index, Computer Source, CSA/Proquest, Current Abstracts, Current Contents/ Life Sciences, Current Contents/Engineering, Computing and Technology, Current Index to Statistics, EMBASE, EMCare, Gale, Google Scholar, Health Reference Center Academic, IBIDS, INIS Atomindex, Inspec, Journal Citation Reports/Science Edition, OCLC, PubMed/Medline, Science & Technology Collection, Science Citation Index, Science Citation Index Expanded (SciSearch), SCOPUS, Summon by Serial Solutions, TOC Premier Instructions to Authors Manuscript submission  Manuscript Submission Submission of a manuscript implies: that the work described has not been published before; that it is not under consideration for publication anywhere else; that its publication has been approved by all co-authors, if any, as well as by the responsible authorities – tacitly or explicitly – at the institute where the work has been carried out. The publisher will not be held legally responsible should there be any claims for compensation. Permissions Authors wishing to include figures, tables, or text passages that have already been published elsewhere are required to obtain permission from the copyright owner(s) for both the print and online format and to include evidence that such permission has been granted when submitting their papers. Any material received without such evidence will be assumed to originate from the authors. Online Submission Authors should submit their manuscripts online. Electronic submission substantially reduces the editorial processing and reviewing times and shortens overall publication times. Please follow the hyperlink “Submit online” on the right and upload all of your manuscript files following the instructions given on the screen. Author tools to prepare your article  For your convenience, Springer has developed macros and templates to help you prepare your article. For information about the preferred format for this journal please refer to the Instructions for Authors. Word template The document template provides predefined style formats for all the types of content that are part of an article. It can be used with Word 2000 and higher. Word template LaTeX macro package The LaTex2e macro package supports various journal layouts. For information about which layout option to use, please refer to the section "Text" on the right. LaTeX macro package Article Types  Contributions should meet the requirements outlined below to avoid delay in review and publication. Manuscripts may be submitted in the following categories: Original Research Articles These regular publications describe original contributions to the advancement of Medical and Biological Engineering and Computing. Recommended length: not exceeding 6000 words including title page, abstract, text, references, tables, and figure legends. The main text of Original Research Articles should contain the following separate sections: Introduction, Methods, Results, Discussion. The maximum number of figures and tables together is 8. Rapid Communication This fast track is intended for exciting novel findings that are expected to have a high impact in the field of Biomedical Engineering. Total length: not exceeding 3000 words. The maximum number of figures and tables together is 5. Based on first judgment of the editors the manuscripts are sent out for accelerated review. Only minor revisions are allowed. When accepted the paper will appear in the journal with priority. Rapid communications should have an Introduction, Methods, Results, and Conclusions section. Technical Notes These are short accounts of novel techniques with preliminary observations or new interpretations of old data, likely to be helpful to others but not meriting a fully-documented paper. Total length: Not exceeding 3000 words. The maximum number of figures and tables together is 6. MBEC is not intended to be a medium for the communication of software practice. The main text of Technical Notes should contain an Introduction, combined Methods and Results section, and Conclusions. Review A review presents a critical survey of the current state of knowledge in a specific bioengineering field. The material contained in reviews need not be original, but the presentation and treatment should be new. Review articles should be organized with an introduction followed by several subsections, and end with a summarizing or concluding section. Such articles are by invitation only and authors intending to submit a review are advised to first contact the Editor-in-Chief (mbec@amc.nl) with an outline proposal. Total length: Normally not more than 8000 words, including references. In exceptional cases more words may be allowed with prior consent of the Editor in Chief. Controversies Two papers with opposing views can be published in MBEC to highlight and contrast differing views in a certain area. In case someone feels that such controversy deserves attention he/she may suggest to the editor to invite authors for each paper. Editorial An editorial will be by invitation only and will present an opinion on an actual scientific theme which may include economic or social relevance. Total length: Not exceeding 3000 words. Letters to the Editor This category is intended for either giving advance reports of important work or for commenting on previously published contributions, especially regarding ambiguities or questions of theory or method. Total length: Not exceeding 1500 words. If a letter is found acceptable by the editor, the author of the article under discussion will have the opportunity to submit a response that will also be considered for publication. Letters in Clinical Engineering In order to stimulate the scientific exchange of information in the field of Clinical Engineering, short publications in the form of ‘Letter’ (see above) are encouraged. These articles are intended to provide the opportunity to disseminate novel clinically relevant methodologies which do not warrant the form of original publications or technical notes. Special issues A special issue is focused on a timely topic and consists of a balanced combination of reviews, original papers and other types of material. Special issues are developed under the guidance of Guest Editors but the final responsibility remains with the Editor in Chief. Special issues are by invitation only, but suggestions to the Editor in Chief are always welcome. Main Text  Introduction Provide a context and rationale for the study (i.e., the nature of the problem and its relevance) in a relatively non-specialized style that can be understood by non-experts in the field. Use only pertinent references to preceding work of others or prior work by own group State the research objective of the study, or hypothesis tested and avoid presenting data or conclusions from the present work being reported. Refrain from listing the organization of subsequent sections. A typical introduction should not exceed 700 words. Methods If pertinent, the section may be divided into headed subsections. Extensive derivations or technical detail should be placed in an Appendix but preferably submitted as Supplementary Material that is published electronically by uploading files under ‘Supplementary Material’. Reference to such material should be made at the appropriate place in the text. Selection and description of patients or laboratory animals Clearly describe the selection criteria for the observational or experimental participants, including controls where appropriate. This section should contain statements on compliance with the Declaration of Helsinki (for studies involving human subjects) and/or the Guiding Principles in the Care and Use of Animals (for studies involving animals). Where relevant, include statements on approval by the local Committee for Animal Experiments and/or the institutional Medical Ethics Review Board. In case of human subjects, a statement should be provided that proper informed consent was obtained. Procedural information Identify the methods, instrumentation and software used (provide manufacturer’s name and address in parentheses), and describe procedures in sufficient detail to allow other scientists to reproduce the results. Specify new or substantially modified methods, and list relevant assumptions and/or limitations. For methods that have been published previously, provide brief descriptions and references. Statistics Describe statistical methods with enough detail to enable a knowledgeable reader with access to the original data to verify the reported results. Avoid relying solely on statistical hypothesis testing, such as the use of P values, which fails to convey important information about effect size. References for the design of the study and statistical methods should be to standard works when possible (with inclusive page numbers stated). Define statistical terms and abbreviations and specify the statistical software used. Results If pertinent, the section may be divided into headed subsections. Present your results in logical sequence in the text, making use of tables and illustrations, and starting with the main or most important findings when possible. Emphasize or summarize only pertinent observations and avoid repeating in the text all the data in the tables or illustrations. Restrict tables and figures to those needed to explain the main arguments of the paper and to support its conclusions. Graphical illustrations are preferred over tables with many entries; do not duplicate data in graphs and tables. When possible, quantify findings and present them with appropriate indicators of measurement error or uncertainty (such as standard deviation or confidence intervals). When summarizing numerical data as derivatives (for example, percentages) also provide the basis in absolute terms from which the derivatives were calculated. Discussion Avoid repetition detailed data or other material given in the Introduction or the Results section. For experimental studies it is useful to begin the discussion by summarizing briefly the main findings, then explore possible mechanisms or explanations for these findings, and compare and contrast the data with regard to previous relevant work by yourself and others. Emphasize the new and important aspects of the study and the conclusions that follow from them. State the limitations of the study including implications of major assumptions made. Explore the impact of the findings for future research and/or clinical practice. Avoid unqualified statements and conclusions not adequately supported by the data. State new hypotheses when warranted, but clearly indicate them as such. Title Page  The title page should include: A concise and informative title The name(s) of the author(s) The affiliation(s) and address(es) of the author(s) The e-mail address, telephone and fax numbers of the corresponding author The total number of words of the manuscript, including entire text from title page to figure legends The number of words of the abstract The number of figures The number of tables Abstract Each paper must be preceded by an abstract presenting the most important results and conclusions in no more than 200 words. It should state the rationale for the study and main objective, methods used, summary of findings, and brief conclusions. Abbreviations should be kept to a minimum. Abstracts are important to convince potential reviewers to accept an invitation to review a manuscript. Keywords Up to five keywords should be supplied after the Abstract for indexing purposes. Keywords should preferably be taken from the Glossary of Terms When only a few symbols and terms are used, define each one when it is first introduced. The definition should include: the symbol its name a definition in words and units (in parentheses) In case many terms and equations are used, a Glossary of Terms may be necessary that should be placed after the Keywords section. Internationally accepted biochemical abbreviations such as ADP and NADH do not need to be defined. Text  Text Formatting Manuscripts should be submitted in Word. Use a normal, plain font (e.g. 11-point Times Roman or 10-point Arial) for text. Use italics for emphasis. Use the automatic page numbering function to number the pages. Do not use field functions. Use tab stops or other commands for indents, not the space bar. Use the table function, not spreadsheets, to make tables. Use the equation editor or MathType for equations. Note: If you use Word 2007, do not create the equations with the default equation editor but use the Microsoft equation editor or MathType instead. Save your file in doc format. Do not submit docx files. For special purposes, such as for mathematical vectors, use boldface type. Units should be given in accordance with the International System of Units (SI units) or their derivates, followed by non-SI units between parentheses when appropriate. Units with more than two factors should preferably be written using superscripts, without slashes (e.g. ml g-1 min-1 instead of ml/g/min). Headings Please use the decimal system of headings with no more than three levels. Abbreviations Abbreviations should be defined at first mention and used consistently thereafter. Footnotes Footnotes can be used to give additional information, which may include the citation of a reference included in the reference list. They should not consist solely of a reference citation, and they should never include the bibliographic details of a reference. They should also not contain any figures or tables. Footnotes to the text are numbered consecutively; those to tables should be indicated by superscript lower-case letters (or asterisks for significance values and other statistical data). Footnotes to the title or the authors of the article are not given reference symbols. Always use footnotes instead of endnotes. Acknowledgments Acknowledgments of people, grants, funds, etc. should be placed in a separate section before the reference list. The names of funding organizations should be written in full. In case individuals are acknowledged for an intellectual contribution, critical review, or technical help, authors are responsible for obtaining written permission from the persons acknowledged by name. References  General Considerations Regarding References The author is responsible for the accuracy of the references. To minimize citation errors, authors should verify references against the original documents. All listed references must be cited in the text. References should be limited to pertinent works or papers that have been published or accepted for publication in journals covered by major scientific databases. An abstract or paper published in conference proceedings, research reports, or theses may be cited only when it is the sole source. An internet address as source for a reference is only allowed when it points to a peer reviewed electronic journal. In case a reference points to a foreign language journal, the language should be provided in square brackets (e.g. [publication in French]). This is also only allowed when it is the sole source. Avoid citing a personal communication unless it provides essential information not available from a public source, in which case the name of the person and date of communication should be cited in parentheses in the text. Authors should obtain written permission and confirmation of accuracy from the source of a personal communication. Although references to review articles can be an efficient way of guiding readers to a body of literature, review articles do not always reflect recent original work. Authors should therefore provide a balanced list of references to original research sources and review articles in order to avoid extensive lists of references that use excessive words and space on the printed page. Usually, this can be achieved with fewer than 30 references. Reference Style and Format The list of references should be alphabetically by the last name of the first author, and numbered serially. Citations in the text should be identified by appropriate numbers in square brackets, and consecutive references should be concatenated (e.g. [7, 12-15]). The names of all authors should be listed. References by the same author or group of authors should be listed in chronological order. Journal titles should be properly abbreviated according to ISSN List of Title Word Abbreviations, see http://www.issn.org/2-22661-LTWA-online.php References should be styled as follows, with correct punctuation: Journal articles: Only the first word is capitalized in the title of the article. Wahle A, Prause GPM, von Birgelen C, Erbel R, Sonka M (1999) Fusion of angiography and intravascular ultrasound in vivo: Establishing the absolute 3-D frame orientation. IEEE Trans Biomed Eng 46:1176-1180 Articles which have been accepted for publication should be listed with the expected year of publication (if known) and name of the journal. In place of volume and page numbers, add (in press) at the end. Books: Main words of book title are capitalized. Provide inclusive page numbers when possible. Nichols W, O'Rourke M (1998) McDonald's Blood Flow in Arteries: Theoretic, Experimental and Clinical Principles. 3rd ed. Lea & Febiger, Philadelphia, pp 54-97 South J, Blass B (2001) The Future of Modern Genomics. Blackwell, London, pp 32-56 Chapter in multi-author books: Provide editor(s), publisher, place, and inclusive page numbers. Hovind HJ (1986) Traumatic birth injuries. In: Raimondi AJ, Choux M, Di Rocco C (eds) Head Injuries in the Newborn and Infant. Principles of Pediatric Neurosurgery, Springer, Berlin Heidelberg New York, pp 87–109 Nyary I, Vajda J (1986) Clinical evidence for compressed lacunar veins causing plateau waves. In: Miller JD, Teasdale GM, Rowan JO, Galbraith SL, Mendelow AD (eds), Intracranial Pressure, vol. VI, Springer, Berlin, pp 142–145 Abstract in journal: Like Journal article, but add (abstract) at end. Article in conference proceedings: Like chapter in book, but provide name of conference proceedings, editors, publisher and place, and page number(s). If applicable, include volume, organizer and conference location. Author (Year) Title of article. In: Editor(s) of proceedings, Conference Name, Publisher, Place, Pages. Conference Location and Organization may be used in case Publisher and Place are not available. Some examples are given here: Holzapfel GA, Schulze-Bauer CAJ, Stadler M (2000) Mechanics of angioplasty: Wall, balloon and stent. In: Casey J, Bao G (eds) Mechanics in Biology. The American Society of Mechanical Engineers; New York, AMD-Vol. 242/BED-Vol. 46, pp 141–156 Itho K, Hayashi T, Muramoto A, Miyakawa M (1997) Controllability of temporomandibular joint loading by masculation: an analysis using a two-dimension static model incorporating a spring mode of the articular disk. In: Jeager R, Agarwal G, Mykleburst B, Feinberg B (eds) Proceedings of the 19th International Conference of the IEEE Engineering in Medicine and Biology Society, Chicago, Part 4 of 6, IEEE Service Center, Piscataway, NJ, pp1847-1848. Also available from CD-ROM, #85 Sonka M, Zhang X, Siebes M, Chada RR, McKay CM, Collins SM (1994) Automated detection of wall and plaque borders in intravascular ultrasound images. In: Hoffman EA, Acharya RS (eds) Medical Imaging 1994: Physiology and Function from Multidimensional Images, SPIE 2168, Society of Photo-Optical Instrumentation Engineers, Bellingham, pp 13-22 Svensson J, Gårdhagen R, Heiberg E, Ebbers T, Loyd D, Länne T, Karlsson M (2006) Feasibility of Patient Specific Aortic Blood Flow CFD Simulation. In: Larsen R, Nielsen M, Sporring J (eds) 10th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI), LNCS 4190, Springer, Berlin Heidelberg New York, pp 257–263. DOI 10.1007/11866565 PhD Thesis: Note: Avoid citing a Master’s Thesis which is generally not available to the public. Dekker LRC (1996) Role of intracellular calcium in ischemic damage and preconditioning in cardiac muscle. PhD Thesis, University of Amsterdam, Amsterdam, The Netherlands Internet page: Try to avoid reference to an internet page and when needed do so in the text between brackets. Internet pages often change or disappear. Sometimes, internet pages are steady (subject to judgment of the Editor) and incorporation in the reference list is allowed. In that case make sure the reference is both current and complete. Parker KH (2008) An introduction to wave intensity analysis. http://www.bg.ic.ac.uk/research/intro_to_wia/welcome.html Accessed 23 Sept 2009 Weisstein E (2008) Correlation coefficient. Wolfram web resource. http://mathworld.wolfram.com/CorrelationCoefficient.html Accessed 23 Sept 2009 Tables  All tables are to be numbered using Arabic numerals. Tables should always be cited in text in consecutive numerical order. For each table, please supply a table caption (title) explaining the components of the table. Identify any previously published material by giving the original source in the form of a reference at the end of the table caption. Footnotes to tables should be indicated by superscript lower-case letters (or asterisks for significance values and other statistical data) and included beneath the table body. Each (multi-panel) figure and table should be printed on a separate page. Please add corresponding caption below the figure for review purposes only. The placement of figures and tables should be indicated in the left margin. Figure legends must be brief, self-sufficient explanations of the illustrations. Provide units for physical quantities and make sure all axes in diagrams are properly labeled. Please make sure that lettering and line thickness are sufficient to render legible figures at the final scale in the printed article. Photographs should be well-contrasted. If pertinent, magnification should be indicated by scale bars. Artwork  Electronic Figure Submission Supply all figures electronically. Indicate what graphics program was used to create the artwork. For vector graphics, the preferred format is EPS; for halftones, please use TIFF format. MS Office files are also acceptable. Vector graphics containing fonts must have the fonts embedded in the files. Name your figure files with "Fig" and the figure number, e.g., Fig1.eps. Submit all figures as separate files and do not integrate them within the text. Line Art Definition: Black and white graphic with no shading. Do not use faint lines and/or lettering and check that all lines and lettering within the figures are legible at final size. All lines should be at least 0.1 mm (0.3 pt) wide. Scanned line drawings and line drawings in bitmap format should have a minimum resolution of 1200 dpi. Vector graphics containing fonts must have the fonts embedded in the files. Halftone Art Definition: Photographs, drawings, or paintings with fine shading, etc. If any magnification is used in the photographs, indicate this by using scale bars within the figures themselves. Halftones should have a minimum resolution of 300 dpi. Combination Art Definition: a combination of halftone and line art, e.g., halftones containing line drawing, extensive lettering, color diagrams, etc. Combination artwork should have a minimum resolution of 600 dpi. Color Art Color art is free of charge for online publication. If black and white will be shown in the print version, make sure that the main information will still be visible. Many colors are not distinguishable from one another when converted to black and white. A simple way to check this is to make a xerographic copy to see if the necessary distinctions between the different colors are still apparent. If the figures will be printed in black and white, do not refer to color in the captions. Color illustrations should be submitted as RGB (8 bits per channel). Figure Lettering To add lettering, it is best to use Helvetica or Arial (sans serif fonts). Keep lettering consistently sized throughout your final-sized artwork, usually about 2–3 mm (8–12 pt). Variance of type size within an illustration should be minimal, e.g., do not use 8-pt type on an axis and 20-pt type for the axis label. Avoid effects such as shading, outline letters, etc. Do not include titles or captions within your illustrations. Figure Numbering All figures are to be numbered using Arabic numerals. Figures should always be cited in text in consecutive numerical order. Figure parts should be denoted by lowercase letters (a, b, c, etc.). If an appendix appears in your article and it contains one or more figures, continue the consecutive numbering of the main text. Do not number the appendix figures, "A1, A2, A3, etc." Figures in online appendices (Electronic Supplementary Material) should, however, be numbered separately. Figure Captions Each figure should have a concise caption describing accurately what the figure depicts. Include the captions in the text file of the manuscript, not in the figure file. Figure captions begin with the term Fig. in bold type, followed by the figure number, also in bold type. No punctuation is to be included after the number, nor is any punctuation to be placed at the end of the caption. Identify all elements found in the figure in the figure caption; and use boxes, circles, etc., as coordinate points in graphs. Identify previously published material by giving the original source in the form of a reference citation at the end of the figure caption. Figure Placement and Size When preparing your figures, size figures to fit in the column width. For most journals the figures should be 39 mm, 84 mm, 129 mm, or 174 mm wide and not higher than 234 mm. For books and book-sized journals, the figures should be 80 mm or 122 mm wide and not higher than 198 mm. Permissions If you include figures that have already been published elsewhere, you must obtain permission from the copyright owner(s) for both the print and online format. Please be aware that some publishers do not grant electronic rights for free and that Springer will not be able to refund any costs that may have occurred to receive these permissions. In such cases, material from other sources should be used. Electronic Supplementary Material  Springer accepts electronic multimedia files (animations, movies, audio, etc.) and other supplementary files to be published online along with an article or a book chapter. This feature can add dimension to the author's article, as certain information cannot be printed or is more convenient in electronic form. Submission Supply all supplementary material in standard file formats. Please include in each file the following information: article title, journal name, author names; affiliation and e-mail address of the corresponding author. To accommodate user downloads, please keep in mind that larger-sized files may require very long download times and that some users may experience other problems during downloading. Audio, Video, and Animations Always use MPEG-1 (.mpg) format. Text and Presentations Submit your material in PDF format; .doc or .ppt files are not suitable for long-term viability. A collection of figures may also be combined in a PDF file. Spreadsheets Spreadsheets should be converted to PDF if no interaction with the data is intended. If the readers should be encouraged to make their own calculations, spreadsheets should be submitted as .xls files (MS Excel). Specialized Formats Specialized format such as .pdb (chemical), .wrl (VRML), .nb (Mathematica notebook), and .tex can also be supplied. Collecting Multiple Files It is possible to collect multiple files in a .zip or .gz file. Numbering If supplying any supplementary material, the text must make specific mention of the material as a citation, similar to that of figures and tables. Refer to the supplementary files as “Online Resource”, e.g., "... as shown in the animation (Online Resource 3)", “... additional data are given in Online Resource 4”. Name the files consecutively, e.g. “ESM_3.mpg”, “ESM_4.pdf”. Captions For each supplementary material, please supply a concise caption describing the content of the file. Processing of supplementary files Electronic supplementary material will be published as received from the author without any conversion, editing, or reformatting. Accessibility In order to give people of all abilities and disabilities access to the content of your supplementary files, please make sure that The manuscript contains a descriptive caption for each supplementary material Video files do not contain anything that flashes more than three times per second (so that users prone to seizures caused by such effects are not put at risk) After acceptance  Upon acceptance of your article you will receive a link to the special Author Query Application at Springer’s web page where you can sign the Copyright Transfer Statement online and indicate whether you wish to order OpenChoice, offprints, or printing of figures in color. Once the Author Query Application has been completed, your article will be processed and you will receive the proofs. Open Choice In addition to the normal publication process (whereby an article is submitted to the journal and access to that article is granted to customers who have purchased a subscription), Springer provides an alternative publishing option: Springer Open Choice. A Springer Open Choice article receives all the benefits of a regular subscription-based article, but in addition is made available publicly through Springer’s online platform SpringerLink. We regret that Springer Open Choice cannot be ordered for published articles. Springer Open Choice Copyright transfer Authors will be asked to transfer copyright of the article to the Publisher (or grant the Publisher exclusive publication and dissemination rights). This will ensure the widest possible protection and dissemination of information under copyright laws. Open Choice articles do not require transfer of copyright as the copyright remains with the author. In opting for open access, they agree to the Springer Open Choice Licence. Offprints Offprints can be ordered by the corresponding author. Color illustrations Online publication of color illustrations is free of charge. For color in the print version, authors will be expected to make a contribution towards the extra costs. Proof reading The purpose of the proof is to check for typesetting or conversion errors and the completeness and accuracy of the text, tables and figures. Substantial changes in content, e.g., new results, corrected values, title and authorship, are not allowed without the approval of the Editor. After online publication, further changes can only be made in the form of an Erratum, which will be hyperlinked to the article. Online First The article will be published online after receipt of the corrected proofs. This is the official first publication citable with the DOI. After release of the printed version, the paper can also be cited by issue and page numbers. Editorial Board Editor-in-chief Jos A. E. Spaan Department of Medical Physics University of Amsterdam Academic Medical Center PO Box 22700, 1100 DE Amsterdam The Netherlands Email: MBEC@amc.nl Deputy Editor Ruben Coronel Academic Medical Center Meibergdreef 9 1105 AZ Amsterdam The Netherlands Email: r.coronel@amc.uva.nl Associate Editors Jenny Dankelman, University of Technology, Delft, The Netherlands Dario Farina, Aalborg University, Aalborg, Denmark Nico A.M. Schellart, Academic Medical Center, Amsterdam, The Netherlands Maria Siebes, Academic Medical Center, Amsterdam, The Netherlands Andreas Wahle, University of Iowa, Iowa, USA Editorial Board Jordi Aguilo, Centre Nacional de Microelectrónica, Barcelona, Spain Gerhard M. Artmann, University of Applied Sciences, Aachen, Germany Dan L. Bader, Queen Mary University, London, UK Chris D. Bertram, University of New South Wales, Sydney, Australia Sergio Cerutti, Politecnico di Milano, Milan, Italy Olaf Dössel, University of Karlsruhe, Germany Ivar Giaever, Rensselaer Polytechnic Institute, Troy, NY, USA Masami Goto, Kawasaki Medical School, Okayama, Japan Warren M. Grill, Duke University, Durham, NC, USA Franc Jager, University of Ljubljana,, Ljubljana, Slovenia Sun I Kim, Hanyang University, Seoul, Korea Chwee Teck Lim, National University of Singapore, Singapore Rod Lakes, University of Wisconsin, Madison, WI, USA Peter W. Macfarlane, University of Glasgow, UK Ronney B. Panerai, Leicester Royal Infirmary, Leicester, UK Nic Smith, University of Oxford, Oxford, UK Leif Sörnmo, Lund University, Lund, Sweden Tatsuo Togawa, Waseda University, Saitama, Japan Andreas Wahle, University of Iowa, Iowa City, IA, USA Karin Wårdell, Linköping University, Linköping, Sweden Federation Journal Committee Chairman Herbert Voigt, USA Members James Goh, Singapore David Holder, United Kingdom Shankar M. Krishnan, USA. Jos A.E. Spaan, MBEC Editor in Chief