期刊名称：JOURNAL OF BIOMOLECULAR NMR
 期刊简介(About the journal)
投稿须知(Instructions to Authors)
编辑部信息(Editorial Board)
About the journal
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The Journal of Biomolecular NMR provides a forum for publishing research on technical developments and innovative applications of nuclear magnetic resonance spectroscopy for the study of structure and dynamic properties of biopolymers in solution, liquid crystals, solids and mixed environments, e.g., attached to membranes. This may include:
- Three-dimensional structure determination of biological macromolecules (polypeptides/proteins, DNA, RNA, oligosaccharides) by NMR.
- New NMR techniques for studies of biological macromolecules.
- Novel approaches to computer-aided automated analysis of multidimensional NMR spectra.
- Computational methods for the structural interpretation of NMR data, including structure refinement.
- Comparisons of structures determined by NMR with those obtained by other methods, e.g. by diffraction techniques with protein single crystals.
- New techniques of sample preparation for NMR experiments (biosynthetic and chemical methods for isotope labeling, preparation of nutrients for biosynthetic isotope labeling, etc.). An NMR characterization of the products must be included.
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Instructions to Authors
Manuscript Submission
For the purpose of reviewing, articles for publication should be submitted as hard-copy printout (fivefold) and electronically to one of the Associate Editors (see above). The storage medium for your electronic manuscript can be a diskette, zip disk or CD-ROM. Please label your diskette properly, giving exact details on the name(s) of the file(s), the operating system and software used. Always save your electronic manuscript in the word processor format that you use; conversions to other formats and versions tend to be imperfect. In general, use as few formatting codes as possible. For safety‘s sake, you should always retain a backup copy of your file(s). After acceptance, please make absolutely sure that you send the latest (i.e., revised) version of your manuscript, both as hard-copy printout and on diskette (submission in electronic form of the final version of your article is compulsory).
Kluwer Academic Publishers prefer articles submitted in word processing packages such as MS Word, WordPerfect, etc. running under operating systems MS DOS, Windows and Apple Macintosh, or in the file format LaTeX. Articles submitted in other software programs can also be accepted.
For submission in LaTeX, Kluwer Academic Publishers have developed a Kluwer LaTeX class file, which can be downloaded from: http://www.wkap.nl/authors/jrnlstylefiles/
Use of this class file is highly recommended. Do not use versions downloaded from other sites. Technical support is available at: texhelp@wkap.nl. If you are not familiar with TeX/LaTeX, the class file will be of no use to you. In that case, submit your article in a common word processor format.
Manuscript Presentation
The journal‘s language is English. British English or American English spelling and terminology may be used, but either one should be followed consistently throughout the article. Manuscripts should be printed or typewritten on A4 or US Letter bond paper, one side only, leaving adequate margins on all sides to allow reviewers?remarks. Please double-space all material, including notes and references. Quotations of more than 40 words should be set off clearly, either by indenting the left-hand margin or by using a smaller typeface. Use double quotation marks for direct quotations and single quotation marks for quotations within quotations and for words or phrases used in a special sense.
Number the pages consecutively with the first page containing the article type, title, author(s), affiliation, full address for correspondence, including phone, fax and e-mail number, 5 to 10 key words in alphabetical order, a short summary of 100 to 250 words, and abbreviations if applicable. The summary and the key words should be as informative as possible.
Manuscript types
Article (regular full-length paper), Communication, Letter to the Editor: New NMR Structure and Letter to the Editor: New NMR Assignment.
Special comment on manuscripts describing new NMR structures
For guidance to the preparation of manuscripts describing the determination of new NMR structures of biological macromolecules with the use of established methodology, authors are referred to Recommendations for the Presentation of NMR Structures of Proteins and Nucleic Acids (Markley, J.L. et al. (1998) J. Biomol. NMR, 12, 1-23). New structures may be published either as an Article or as a Letter to the Editor: New NMR structure. The principal criteria for deciding about the appropriate format for the publication are novelty of the structure, and the biological interest of the work presented. At the discretion of the Associate Editor to whom the manuscript has been submitted, the authors may be asked to change the format from that of an Article to a Letter to the Editor: New NMR structure, or vice versa. Such a decision may be made either before the manuscript is accepted for review, or after the initial review in view of the referee‘s comments.
Requirements for deposition of data
Atomic coordinates must be deposited in the Protein Data Bank (PDB) and, unless presented elsewhere previously, the resonance assignments must be deposited with the BioMagResBank (BMRB; http://www.bmrb.wisc.edu). All manuscripts submitted for review describing either new structures or assignments must include the PDB and/or BMRB accession numbers, and on a separate sheet the acknowledgement of receipt by the database, including the hidden access code (BMRB), required for reviewing purposes. Deposited data must be released at the latest on the date of publication.
Article
Full-length papers should conform to a sectional format, usually including Title, Summary, Key words, Introduction, Materials and Methods, Results, Discussion, Conclusions, Acknowledgements and References. Descriptions of novel experimental or computational procedures should include sufficient detail to enable others to repeat these procedures. Use of published procedures should merely be referred to by literature citation of both the original experiment and any published modifications. Manuscripts describing computer programs should include a statement how access to this software can be obtained. Articles of outstanding quality and interest may be processed as ’accelerated publication? with the same priority for rapid publication as a Communication.
Communication
Communications are restricted to reports of unusual urgency, significance, and interest, and must fit on 6 printed pages, including figures, tables and references (see Sizing guide section). Each Communication should be accompanied by a summary identifying in 100 words or less the major observation reported, and 4-6 key words. Communications should not be sectionalized. The authors should point out in their cover letter why they believe the manuscript meets the criteria of unusual urgency, significance or interest.
Letter to the Editor: New NMR structure
A structure determination that yields a high quality NMR structure but may not warrant description in an Article can be published as a Letter to the Editor: New NMR structure. Possible examples for such submissions are high quality structures of biologically interesting molecules that are homologous to previously published structures, of gene products with unknown function, etc. Preliminary reports on incomplete or unrefined structures are not acceptable and will be returned to the authors without being reviewed. The manuscript must follow the layout of J. Biomol. NMR, 19, 75-78 (2001), with the three subtitles: Biological context, Methods and results, and Discussion and conclusions. The text may be supplemented by up to four items of documentation, for example, one table and three figures. One of the figures must illustrate the NMR data on which the structure determination is based, and the presentation of the structure must include a stereo view that contains the sidechains. Up to 20 references may be cited. A Letter to the Editor: New NMR structure must fit on 4 printed pages (see Sizing guide section).
Letter to the Editor: New NMR assignment
An assignment for a new, well-structured protein of at least 100 residues in size (i.e., data collected under non-denaturing conditions for the active form of the protein) can be published as a Letter to the Editor: New NMR assignment. Residues added in the cloning process that are not part of the native sequence are not to be included in the residue count, and the size of a homo-oligomeric protein is evaluated on the basis of its monomer chain length. A protein is considered "new" if no NMR structure or resonance assignments have yet been published for any protein that is more than 70% identical in sequence. Assignments for proteins that are part of an intermolecular complex cannot be considered if either the NMR structure or assignments for the free protein or for the protein as part of another complex have been published. In case of doubt, authors are advised to contact an Associate Editor prior to preparation of the manuscript. Complete backbone assignments and complete or nearly complete side chain assignments are required. Partial assignments may be considered for publication if the authors present, in the Biological context section, a convincing reason for publication of this data in view of its biological interest. For example, assignments only for the polypeptide backbone in proteins for which a crystal structure is available could provide a basis for functional studies of the protein. In each individual case the decision on whether or not an assignment letter is accepted for review, and hence given a chance for acceptance, is with the Associate Editor to whom the manuscript has been submitted. The manuscript must follow the layout of J. Biomol. NMR, 19, 79-80 (2001), with the three subtitles Biological context, Methods and experiments, and Extent of assignments and data deposition. The text must be supplemented by one figure, illustrating the quality of annotated spectral data underlying the assignments, and at most 10 references. A ‘Letter to the Editor: New NMR Assignment?must fit on two printed pages (see Sizing guide section).
Symbols and Units
SI units should be used.
Nomenclature
All nomenclature should be consistent, conforming to the recommendations of the International Union of Pure and Applied Chemistry, International Union of Biochemistry, and other appropriate bodies.
Figures and TablesSubmission of electronic figures
In addition to hard-copy printouts of figures, authors are requested to supply the electronic versions of figures in either Encapsulated PostScript (EPS) or TIFF format. Many other formats, e.g., Microsoft Postscript, PiCT (Macintosh) and WMF (Windows), cannot be used and the hard copy will be scanned instead.
Figures should be saved in separate files without their captions, which should be included with the text of the article. Files should be named according to DOS conventions, e.g., ’figure1.eps? For vector graphics, EPS is the preferred format. Lines should not be thinner than 0.25 pts and in-fill patterns and screens should have a density of at least 10%. Font-related problems can be avoided by using standard fonts such as Times Roman and Helvetica. For bitmapped graphics, TIFF is the preferred format but EPS is also acceptable. The following resolutions are optimal: black-and-white line figures - 600 - 1200 dpi; line figures with some grey or coloured lines - 600 dpi; photographs - 300 dpi; screen dumps - leave as is. Higher resolutions will not improve output quality but will only increase file size, which may cause problems with printing; lower resolutions may compromise output quality. Please try to provide artwork that approximately fits within the typeset area of the journal. Especially screened originals, i.e. originals with grey areas, may suffer badly from reduction by more than 10-15%. AVOIDING PROBLEMS WITH EPS GRAPHICS
Please always check whether the figures print correctly to a PostScript printer in a reasonable amount of time. If they do not, simplify your figures or use a different graphics program. If EPS export does not produce acceptable output, try to create an EPS file with the printer driver (see below). This option is unavailable with the Microsoft driver for Windows NT, so if you run Windows NT, get the Adobe driver from the Adobe site (www.adobe.com).
If EPS export is not an option, e.g., because you rely on OLE and cannot create separate files for your graphics, it may help us if you simply provide a PostScript dump of the entire document. HOW TO SET UP FOR EPS AND POSTSCRIPT DUMPS UNDER WINDOWS
Create a printer entry specifically for this purpose: install the printer ’Apple Laserwriter Plus?and specify ’FILE? as printer port. Each time you send something to the ’printer?you will be asked for a filename. This file will be the EPS file or PostScript dump that can be used by the publisher. The EPS export option can be found under the PostScript tab. EPS export should be used only for single-page documents. For printing a document of several pages, select ’Optimise for portability?instead. The option ’Download header with each job?should be checked. Submission of hard-copy figures
If no electronic versions of figures are available, submit only high-quality artwork that can be reproduced as is, i.e., without any part having to be redrawn or re-typeset. The letter size of any text in the figures must be large enough to allow for reduction. Photographs should be in black-and-white on glossy paper. If a figure contains colour, make absolutely clear whether it should be printed in black-and-white or in colour. Figures that are to be printed in black-and-white should not be submitted in colour. Authors will be charged for reproducing figures in colour.
Each figure and table should be numbered and mentioned in the text. The approximate position of figures and tables should be indicated in the margin of the manuscript. On the reverse side of each figure, the name of the (first) author and the figure number should be written in pencil; the top of the figure should be clearly indicated. Figures and tables should be placed at the end of the manuscript following the Reference section. Each figure and table should be accompanied by an explanatory legend. The figure legends should be grouped and placed on a separate page. Figures are not returned to the author unless specifically requested. In tables, footnotes are preferable to long explanatory material in either the heading or body of the table. Such explanatory footnotes, identified by superscript letters, should be placed immediately below the table.
Section Headings
First-, second-, third-, and fourth-order headings should be clearly distinguishable but not numbered.
Notes
Please use footnotes rather than endnotes. Notes should be indicated by consecutive superscript numbers in the text. A source reference note should be indicated by means of an asterisk after the title. This note should be placed at the bottom of the first page.
Cross-Referencing
In the text, a reference identified by means of an author‘s name should be followed by the date of the reference in parentheses and page number(s) where appropriate. When there are more than two authors, only the first author‘s name should be mentioned, followed by ’et al.? In the event that an author cited has had two or more works published during the same year, the reference, both in the text and in the reference list, should be identified by a lower case letter like ’a?and ’b?after the date to distinguish the works. Examples:
Winograd (1986, p. 204)
(Winograd, 1986a, b)
(Winograd, 1986; Flores et al., 1988)
(Bullen and Bennett, 1990)
Acknowledgements
Acknowledgements of people, grants, funds, etc. should be placed in a separate section before the References.
References
References to books, journal articles, articles in collections and conference or workshop proceedings, and technical reports should be listed at the end of the article in alphabetical order following the Harvard style (see examples below). Articles in preparation or articles submitted for publication, unpublished observations, personal communications, etc. should not be included in the reference list but should only be mentioned in the article text (e.g., T. Moore, personal communication).
References to books should include the author‘s name(s); year of publication in parentheses; title (in italics); page numbers where appropriate; publisher; place of publication, in the order given in the example below.
Wuthrich, K. (1986) NMR of Proteins and Nucleic Acids, Wiley, New York, NY.
References to articles in an edited collection should include the author‘s name(s); year of publication in parentheses; editor‘s name(s); title of collection (in italics); first and last page numbers; publisher; place of publication, in the order given in the example below.
Norinder, U. (1998) In QSAR in Drug Design, Vol. 3: Recent Advances (Eds., Kubinyi, H., Folkers, G. and Martin, Y.C.), Kluwer, Dordrecht, pp. 25-39.
References to articles in conference proceedings should include the author‘s name(s); year of publication in parentheses; editor‘s name (if any); title of proceedings; first and last page numbers; place and date of conference; publisher and/or organization from which the proceedings can be obtained; place of publication, in the order given in the example below.
Mechnich, O., Hessler, G., Bernd, M., Kutscher, B. and Kessler, H. (1999) In Peptides: Frontiers of Peptide Science (Eds., Tam, J.P. and Kaumaya, P.T.P.), Proceedings of the Fifteenth American Peptide Symposium, Nashville, TN, June 14-19, 1997, Kluwer, Dordrecht, pp. 465-466.
References to articles in periodicals should include the author‘s name(s); year of publication in parentheses; abbreviated title of periodical (in italics); volume number (in bold); first and last page numbers, in the order given in the example below.
Maler, L., Potts, B.C.M. and Chazin, W.J. (1999) J. Biomol. NMR, 13, 233-247.
References to technical reports or doctoral dissertations should include the author‘s name; year of publication in parentheses; title; institution; location of institution, in the order given in the example below.
Burgering, M.J.M. (1994) NMR studies of Arc and Mnt repressors, Ph.D. Thesis, Utrecht University, Utrecht.
Supplementary material. In an effort to keep the length of articles within reasonable limits, provision is made to submit supplementary material. This should be prepared in the same style as the article itself and submitted along with the manuscript for refereeing. If accepted for publication, such articles will contain a statement that supplementary material is available from the corresponding author who agrees to provide this material on request to interested individuals for a period of at least 3 years following the date of publication.
Proofs
Proofs will be sent to the corresponding author by e-mail (if no e-mail address is available or appears to be out of order, proofs will be sent by regular mail).
Your response, with or without corrections, should be sent within 72 hours. Please do not make any changes to the PDF file. Minor corrections (+/- 10) should be sent as an e-mail attachment to: proofscorrection@wkap.nl. Always quote the four-letter journal code and article number and the PIPS No. from your proof in the subject field of your e-mail. Extensive corrections must be clearly marked on a printout of the PDF file and should be sent by first-class mail (airmail overseas).
Offprints
Fifty offprints of each article will be provided free of charge. Additional offprints (both hard copies and PDF files) can be ordered by means of an offprint order form supplied with the proofs.
Page Charges and Colour Figures
No page charges are levied on authors or their institutions. Colour figures are published at the author‘s expense only.
Copyright
Authors will be asked, upon acceptance of an article, to transfer copyright of the article to the Publisher. This will ensure the widest possible dissemination of information under copyright laws.
Permissions
It is the responsibility of the author to obtain written permission for a quotation from unpublished material, or for all quotations in excess of 250 words in one extract or 500 words in total from any work still in copyright, and for the reprinting of figures or tables from unpublished or copyrighted material.
Additional Information
Additional information can be obtained from: Publishing Editor JNMR
Kluwer Academic Publishers
P.O. Box 17
3300 AA Dordrecht
The Netherlands
Phone: 31-78-6576312
Fax: 31-78-6576254
E-mail: peter.butler@wkap.nl
http://www.wkap.nl
Editorial Board
Editor-in-Chief:
Prof.Kurt Wüthrich, Institute for Molecular Biology and Biophysics, ETH-Hönggerberg, CH-8093 Zürich, Switzerland.
Associate Editor:
Dr. Ad Bax , Laboratory of Chemical Physics, NIDDK, Building 5, Room 126, National Institutes of Health, Bethesda, MD 20892-0520, USA.
Tel: +1 (301) 496-2848; Fax: +1 (301) 402-0907; E-mail: bax@nih.gov
Dr. Rob Kaptein , Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.
Tel: +31 (30) 253-3787; Fax: +31 (30) 253-7623; E-mail: kaptein@nmr.chem.uu.nl
Dr. Brian D. Sykes , Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada T6G 2H7.
Tel: +1 (780) 492-5460; Fax: +1 (780) 492-0886; E-mail: brian.sykes@ualberta.ca
Advisory Editor:
Yoji Arata
Genomic Science Center (GSC) RIKEN, Tsurumi, Japan
Editorial Board:
A.S. Arseniev, Russian Academy of Sciences, Moscow, Russia; M. Billeter, Göteborg University, Sweden; I.D. Campbell, University of Oxford, UK; D.A. Case, The Scripps Research Institute, La Jolla, CA, USA; R.R. Ernst, ETH-Zentrum, Zürich, Switzerland; S.W. Fesik, Abbott Laboratories, Abbott Park, IL, USA; S. Grzesiek, Biozentrum, Basel, Switzerland; A.M. Gronenborn, National Institutes of Health, Bethesda, MD, USA; W.F. van Gunsteren, ETH-Zentrum, Zürich, Switzerland; C.W. Hilbers, University of Nijmegen, The Netherlands; M. Kainosho, Tokyo Metropolitan University, Japan; L.E. Kay, University of Toronto, ON, Canada; H. Kessler, Technische Universität München, Garching, Germany; Y. Kyogoku, Osaka University, Japan; C. Luchinat, University of Florence, Italy; J.L. Markley, University of Wisconsin, Madison, USA; D. Neuhaus, MRC Laboratory of Molecular Biology, Cambridge, UK; R.S. Norton, Walter and Eliza Hall Institute of Medical Research, Parkville, Australia; S.J. Opella, University of California, San Diego, USA; G. Otting, Karolinska Institutet, Stockholm, Sweden; A.G. Palmer III, Columbia University, New York, USA; D.J. Patel, Memorial Sloan-Kettering Cancer Center, New York, USA; J.H. Prestegard, (CCRC) University of Georgia, Athens, USA; C. Redfield, Oxford Centre for Molecular Sciences, UK; H.A. Scheraga, Cornell University, Ithaca, NY, USA; M.F. Summers, University of Maryland Baltimore County & HHMI, USA; J.F.G. Vliegenthart, Utrecht University, The Netherlands; G. Wagner, Harvard Medical School, Boston, MA, USA; D.E. Wemmer, University of California at Berkeley, USA; P.E. Wright, The Scripps Research Institute, La Jolla, CA, USA
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