期刊名称：DEVELOPMENTAL BIOLOGY
 期刊简介(About the journal)
投稿须知(Instructions to Authors)
编辑部信息(Editorial Board)
About the journal
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Developmental Biology publishes original research on mechanisms of development, differentiation, and growth in animals and plants at the molecular, cellular, and genetic levels. Areas of particular emphasis include transcriptional control mechanisms, embryonic patterning, cell-cell interactions, growth factors and signal transduction, and regulatory hierarchies.
Research Areas Include:
• Molecular genetics of development
• Control of gene expression
• Cell interactions and cell-matrix interactions
• Mechanisms of differentiation
• Growth factors and oncogenes
• Regulation of stem cell populations
• Gametogenesis and fertilization
• Developmental endocrinology
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Instructions to Authors
Developmental Biology publishes original research on mechanisms of development, differentiation, and growth in animals and plants at the molecular, cellular, and genetic levels. Areas of particular emphasis include transcriptional control mechanisms, embryonic patterning, cell-cell interactions, growth factors and signal transduction, and regulatory hierarchies.
Scientific Guidelines for Authors submitting to Developmental Biology
Developmental Biology's goal is to publish high quality papers providing causal insight into the cellular and molecular mechanisms that govern developmental processes.
Studies which simply confirm an established functional role for a developmental component by presenting analysis in a new species lack sufficient novelty for consideration.
Similarly, purely descriptive spatial gene expression or gene phylogeny articles are not considered for publication unless they are notably of consequence and are of particular value to the field.
Types of paper
Developmental Biology publishes Original Research Papers, Review Articles, Essays, Perspectives, and articles for the Genomes and Developmental Control and Evolution of Developmental Control Mechanisms sections.
Original Research Papers
Developmental Biology seeks to publish only the very best papers that contribute new information to our understanding of developmental mechanisms. Questions are frequently raised about "descriptive" papers. Such papers are appropriate for DB if they provide important new insights. This would not include, for example, a description of the expression pattern of a gene in one species that has already been described in another species, or an expression pattern with no obvious link to a developmental process.
We require that manuscripts specifically address biological relevance. While morpholino, microarray and RNAi studies may be acceptable, they must contain adequate controls to be considered for publication.
The following types of Original Research papers have specific guidelines:
Expression profiling and gene expression studies must contain supporting functional data. Studies solely based on analysis of expression by microarray, northern blots, PCR or in situ hybridization are too descriptive or preliminary to justify full review.
Gene knock-down experiments:
Experiments using interfering DNA or proteins to address gene function are expected to be highly controlled. In particular, experiments with Morpholino, RNAi, siRNA or dominant negative constructs are expected to contain very precise controls to address the specificity of the effects observed.
Studies in which the expression, structure or function of a gene/protein is altered but lead to no phenotypic consequences are not appropriate. Furthermore, studies of mutants which simply show that a gene/protein is required for development will be discouraged unless attempts are made to address the mechanistic basis, causal roles or tissues and processes affected.
Experiments using stem cells must advance our understanding of biological functioning. Studies that simply grow/isolate stem cells from a tissue and show what markers they express are not appropriate.
Studies using cell culture must show direct (in vivo) relevance in a developmental context.
Papers usually do not exceed 15,000 words.
Review Articles
Review articles are intended to reach a broad audience of readers from investigators in the field to new graduate students learning the material for the first time. Review articles are subject to the same review process as original papers, but may receive expedited consideration. Manuscripts should be prepared according to the general guidelines given below. The Materials and Methods, Results, and Discussion sections may be replaced with appropriate alternatives; an abstract is still required. The editor-in-chief and the reviews editor invite inquiries and suggestions for timely and provocative review articles.
Perspectives
Perspectives are short scholarly articles that express an opinion on a body of work, an idea or concept. They may relate to historical material or may honor a specific scientist or technique. They are not, however, letters to the editor or a forum for discussing a specific article or author published in the journal. Word limit: 2,000
Essays
Essays are longer scholarly articles that express an opinion on a body of work, an idea or concept. They may in part review articles covering a narrow topic or controversial field and put forward a hypothesis. Unlike reviews they do not necessarily have to address a topic in its entirety but may concentrate on one specific aspect of research. The work should contain references and figures and generally not contain more than 8,000 words.
Genomes and Developmental Control
The Genomes and Developmental Control section is dedicated to papers that address analysis of developmental cis-regulatory systems; developmental genomics; transcriptional mechanisms in development, analysis of specific developmental processes, and system-level approaches to such networks; comparative analysis and evolution of regulatory systems; and computational advances that illuminate the identification and the structure/function relationships of developmental control systems. Papers selected for this section will appear together on a monthly basis. As always, we are dedicated to rapidly reviewing papers.
Evolution of Developmental Control Mechanisms
The goal of the Evolution of Developmental Control Mechanisms section is to provide a focus on research that examines evolutionary questions from a developmental perspective. The section is not intended for accounts of descriptive observations or for reports of gene expression, but rather for research that illuminates mechanistic differences in processes and causes of evolutionary change in developmental programs. The intersection of embryology and evolution has formed a framework for understanding evolutionary processes since the time of Darwin. The recent availability of genomic sequence information has greatly facilitated identification of homologous genes and their regulatory regions across diverse species, from unicellular organisms to plants, vertebrates, and invertebrates. The advent of powerful tools for performing experimental analyses (RNAi, antisense morpholino oligonucleotides, transgenesis, pharmacological intervention, etc.) now allows testing and comparison of gene deployment and function across diverse species. This section aims to provide a venue of choice for such in-depth comparative functional analyses.
Contact details for submission
Articles for Developmental Biology should be submitted via the journal's online submission system,  http://ees.elsevier.com/developmentalbiology.
Customer support is available 24/7:
Please use our help site at: http://epsupport.elsevier.com/. Here you will be able to learn more about the online submission system via interactive tutorials, explore a range of problem solutions via our knowledgebase, and find answers to frequently asked questions. You will also find our 24/7 support contact details should you need any assistance from one of our customer service representatives.
For questions on the reviewing and submission process, please contact:
Developmental Biology Editorial Office
525 B Street, Suite 1800
San Diego, CA 92101-4495, USA
Tel: (619) 699-6351
Fax: (619) 699-6211
E-mail: db@elsevier.com
Ethics in Publishing
For information on Ethics in Publishing and Ethical guidelines for journal publication see http://www.elsevier.com/publishingethics and http://www.elsevier.com/ethicalguidelines.
Conflict of interest
All authors are requested to disclose any actual or potential conflict of interest including any financial, personal or other relationships with other people or organizations within three years of beginning the submitted work that could inappropriately influence, or be perceived to influence, their work. See also http://www.elsevier.com/conflictsofinterest.
Submission declaration
Submission of an article implies that the work described has not been published previously (except in the form of an abstract or as part of a published lecture or academic thesis), that it is not under consideration for publication elsewhere, that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was carried out, and that, if accepted, it will not be published elsewhere including electronically in the same form, in English or in any other language, without the written consent of the copyright-holder.
Copyright
Upon acceptance of an article, authors will be asked to complete a 'Journal Publishing Agreement' (for more information on this and copyright see http://www.elsevier.com/copyright). Acceptance of the agreement will ensure the widest possible dissemination of information. An e-mail will be sent to the corresponding author confirming receipt of the manuscript together with a 'Journal Publishing Agreement' form or a link to the online version of this agreement.
Subscribers may reproduce tables of contents or prepare lists of articles including abstracts for internal circulation within their institutions. Permission of the Publisher is required for resale or distribution outside the institution and for all other derivative works, including compilations and translations (please consult http://www.elsevier.com/permissions). If excerpts from other copyrighted works are included, the author(s) must obtain written permission from the copyright owners and credit the source(s) in the article. Elsevier has preprinted forms for use by authors in these cases: please consult http://www.elsevier.com/permissions.
Retained author rights
As an author you (or your employer or institution) retain certain rights; for details you are referred to: http://www.elsevier.com/authorsrights.
Role of the funding source
You are requested to identify who provided financial support for the conduct of the research and/or preparation of the article and to briefly describe the role of the sponsor(s), if any, in study design; in the collection, analysis and interpretation of data; in the writing of the report; and in the decision to submit the paper for publication. If the funding source(s) had no such involvement then this should be stated. Please see http://www.elsevier.com/funding.
Funding body agreements and policies
Elsevier has established agreements and developed policies to allow authors whose articles appear in journals published by Elsevier, to comply with potential manuscript archiving requirements as specified as conditions of their grant awards. To learn more about existing agreements and policies please visit http://www.elsevier.com/fundingbodies.
Sponsored articles
This journal offers authors the option to sponsor non-subscriber access to their articles on Elsevier's electronic publishing platforms. For more information please view our Sponsored Articles page at http://www.elsevier.com/wps/find/authors.authors/sponsoredarticles.
Language and language services
Please write your text in good English (American or British usage is accepted, but not a mixture of these). Authors who require information about language editing and copyediting services pre- and post-submission please visit http://www.elsevier.com/languageediting or our customer support site at http://epsupport.elsevier.com for more information.
Submission
Submission to this journal proceeds totally online and you will be guided stepwise through the creation and uploading of your files. The system automatically converts source files to a single PDF file of the article, which is used in the peer-review process. Please note that even though manuscript source files are converted to PDF files at submission for the review process, these source files are needed for further processing after acceptance. All correspondence, including notification of the Editor's decision and requests for revision, takes place by e-mail removing the need for a paper trail.
Referees
Please submit, with the manuscript, the names, addresses and e-mail addresses of 3 potential referees. Note that the editor retains the sole right to decide whether or not the suggested reviewers are used.
Additional information
Cover Submissions
Color figures for exclusive use as cover illustrations may be submitted by authors who are also submitting a manuscript for consideration. Such illustrations do not need to relate to the manuscript being submitted but should relate to the larger scope and focus of Developmental Biology. A legend of 100 or fewer words should accompany each image.
Materials
Publication of a research article in Developmental Biology is taken to imply that the authors are prepared to distribute all non-commercially obtained materials used in the experiments (e.g. cells, DNA, antibodies, primary data), to other academic researchers for their own use or for verification. All nucleic acid and protein sequences must have been deposited in the appropriate databases and the Accession Numbers cited in the paper.
Data from microarray and other similar screens:
Please see the MGED open letter specifying microarray standards at http://www.mged.org/Workgroups/MIAME/miame_checklist.html. Authors submitting manuscripts relying on microarray or similar screens must supply the data as Supplementary data (see below) at the time of submission, along with the completed MIAME checklist. The data must be MIAME-compliant and supplied in a form that is widely accessible. The microarray data must also be submitted to either the GEO ( http://www.ncbi.nlm.nih.gov/geo/) or ArrayExpress ( http://www.ebi.ac.uk/arrayexpress/) databases, with accession numbers at or before acceptance of the paper for publication. The editors understand that on occasion authors may not feel it appropriate to deposit the entire data set at the time of publication of this paper. We are therefore willing to consider exceptions to this requirement in response to a request from the authors, which must be made at the time of initial submission or as part of an informal pre-submission enquiry.
Mouse Gene Expression Data
Upon acceptance of the manuscript for publication in DB, authors reporting mouse gene expression data from RNA in situ hybridization, immunohistochemistry, Northern blot, Western blot and RT-PCR experiments are requested to submit pertinent data to the Mouse Gene Expression Database (GXD). These data submissions will receive accession numbers that may then be inserted into the manuscript. Please see GXD's guidelines for electronic data submission at http://www.informatics.jax.org/mgihome//GXD/GEN/gxd_submission_guidelines.shtml.
US National Institutes of Health (NIH) posting ("Public Access") policy
As a service to our authors, Elsevier will deposit to PubMed Central (PMC) author manuscripts on behalf of Elsevier authors reporting NIH funded research. This service is a continuation of Elsevier's 2005 agreement with the NIH when the NIH introduced their voluntary 'Public Access Policy'. See http://www.elsevier.com/wps/find/authors.authors/nihauthorrequest.
Access to non-subscribers 12 months after publication
Elsevier is pleased to announce that all articles published in Developmental Biology are accessible to non-subscribers 12 months after publication via ScienceDirect ( http://www.sciencedirect.com/science/journal/00121606).
Policy for Wellcome Trust funded authors
http://www.elsevier.com/wps/find/authorshome.authors/wellcometrustauthors.
Use of wordprocessing software
It is important that the file be saved in the native format of the wordprocessor used. The text should be in single-column format. Keep the layout of the text as simple as possible. Most formatting codes will be removed and replaced on processing the article. In particular, do not use the wordprocessor's options to justify text or to hyphenate words. However, do use bold face, italics, subscripts, superscripts etc. Do not embed "graphically designed" equations or tables, but prepare these using the wordprocessor's facility. When preparing tables, if you are using a table grid, use only one grid for each individual table and not a grid for each row. If no grid is used, use tabs, not spaces, to align columns. The electronic text should be prepared in a way very similar to that of conventional manuscripts (see also the Guide to Publishing with Elsevier: http://www.elsevier.com/guidepublication). Do not import the figures into the text file but, instead, indicate their approximate locations directly in the electronic text and on the manuscript. See also the section on Electronic illustrations.
To avoid unnecessary errors you are strongly advised to use the "spell-check" and "grammar-check" functions of your wordprocessor.
Article structure
Introduction
State the objectives of the work and provide an adequate background, avoiding a detailed literature survey or a summary of the results.
Material and methods
Provide sufficient detail to allow the work to be reproduced. Methods already published should be indicated by a reference: only relevant modifications should be described.
Results
Results should be clear and concise.
Discussion
This should explore the significance of the results of the work, not repeat them. A combined Results and Discussion section is often appropriate. Avoid extensive citations and discussion of published literature.
Conclusions
The main conclusions of the study may be presented in a short Conclusions section, which may stand alone or form a subsection of a Discussion or Results and Discussion section.
Essential title page information
• Title. Concise and informative. Titles are often used in information-retrieval systems. Avoid abbreviations and formulae where possible.
• Author names and affiliations. Where the family name may be ambiguous (e.g., a double name), please indicate this clearly. Present the authors' affiliation addresses (where the actual work was done) below the names. Indicate all affiliations with a lower-case superscript letter immediately after the author's name and in front of the appropriate address. Provide the full postal address of each affiliation, including the country name, and, if available, the e-mail address of each author.
• Corresponding author. Clearly indicate who will handle correspondence at all stages of refereeing and publication, also post-publication. Ensure that telephone and fax numbers (with country and area code) are provided in addition to the e-mail address and the complete postal address.
• Present/permanent address. If an author has moved since the work described in the article was done, or was visiting at the time, a "Present address" (or "Permanent address") may be indicated as a footnote to that author's name. The address at which the author actually did the work must be retained as the main, affiliation address. Superscript Arabic numerals are used for such footnotes.
Abstract
A concise and factual abstract is required. The abstract should state briefly the purpose of the research, the principal results and major conclusions. An abstract is often presented separately from the article, so it must be able to stand alone. For this reason, References should be avoided, but if essential, then cite the author(s) and year(s). Also, non-standard or uncommon abbreviations should be avoided, but if essential they must be defined at their first mention in the abstract itself.
Graphical abstract
A Graphical abstract is optional and should summarize the contents of the paper in a concise, pictorial form designed to capture the attention of a wide readership online. Authors must provide images that clearly represent the work described in the paper. Graphical abstracts should be submitted as a separate file in the online submission system. Maximum image size: 400 × 600 pixels (h × w, recommended size 200 × 500 pixels). Preferred file types: TIFF, EPS, PDF or MS Office files. See http://www.elsevier.com/graphicalabstracts for examples.
Keywords
Immediately after the abstract, provide a maximum of 6 keywords, using American spelling and avoiding general and plural terms and multiple concepts (avoid, for example, "and", "of"). Be sparing with abbreviations: only abbreviations firmly established in the field may be eligible. These keywords will be used for indexing purposes.
Acknowledgements
Collate acknowledgements in a separate section at the end of the article before the references and do not, therefore, include them on the title page, as a footnote to the title or otherwise. List here those individuals who provided help during the research (e.g., providing language help, writing assistance or proof reading the article, etc.).
Accession numbers
Accession numbers are unique identifiers in bioinformatics allocated to nucleotide and protein sequences to allow tracking of different versions of that sequence record and the associated sequence in a data repository [e.g., databases at the National Center for Biotechnical Information (NCBI) at the National Library of Medicine ('GenBank') and the Worldwide Protein Data Bank]. There are different types of accession numbers in use based on the type of sequence cited, each of which uses a different coding. Authors should explicitly mention the type of accession number together with the actual number, bearing in mind that an error in a letter or number can result in a dead link in the online version of the article. Please use the following format: accession number type ID: xxxx (e.g., MMDB ID: 12345; PDB ID: 1TUP). Note that in the final version of the electronic copy, accession numbers will be linked to the appropriate database, enabling readers to go directly to that source from the article.
Artwork
Electronic artwork
General points
• Make sure you use uniform lettering and sizing of your original artwork.
• Save text in illustrations as "graphics" or enclose the font.
• Only use the following fonts in your illustrations: Arial, Courier, Times, Symbol.
• Number the illustrations according to their sequence in the text.
• Use a logical naming convention for your artwork files.
• Provide captions to illustrations separately.
• Produce images near to the desired size of the printed version.
• Submit each figure as a separate file.
A detailed guide on electronic artwork is available on our website:
http://www.elsevier.com/artworkinstructions
You are urged to visit this site; some excerpts from the detailed information are given here.
Formats
Regardless of the application used, when your electronic artwork is finalised, please "save as" or convert the images to one of the following formats (note the resolution requirements for line drawings, halftones, and line/halftone combinations given below):
EPS: Vector drawings. Embed the font or save the text as "graphics".
TIFF: color or grayscale photographs (halftones): always use a minimum of 300 dpi.
TIFF: Bitmapped line drawings: use a minimum of 1000 dpi.
TIFF: Combinations bitmapped line/half-tone (color or grayscale): a minimum of 500 dpi is required.
DOC, XLS or PPT: If your electronic artwork is created in any of these Microsoft Office applications please supply "as is".
Please do not:
• Supply embedded graphics in your wordprocessor (spreadsheet, presentation) document;
• Supply files that are optimised for screen use (like GIF, BMP, PICT, WPG); the resolution is too low;
• Supply files that are too low in resolution;
• Submit graphics that are disproportionately large for the content.
Color artwork
Please make sure that artwork files are in an acceptable format (TIFF, EPS or MS Office files) and with the correct resolution. If, together with your accepted article, you submit usable color figures then Elsevier will ensure, at no additional charge, that these figures will appear in color on the Web (e.g., ScienceDirect and other sites) in addition to color reproduction in print. For further information on the preparation of electronic artwork, please see http://www.elsevier.com/artworkinstructions.
Figure captions
Ensure that each illustration has a caption. Supply captions separately, not attached to the figure. A caption should comprise a brief title (not on the figure itself) and a description of the illustration. Keep text in the illustrations themselves to a minimum but explain all symbols and abbreviations used.
Tables
Number tables consecutively in accordance with their appearance in the text. Place footnotes to tables below the table body and indicate them with superscript lowercase letters. Avoid vertical rules. Be sparing in the use of tables and ensure that the data presented in tables do not duplicate results described elsewhere in the article.
References
Citation in text
Please ensure that every reference cited in the text is also present in the reference list (and vice versa). Any references cited in the abstract must be given in full. Unpublished results and personal communications are not recommended in the reference list, but may be mentioned in the text. If these references are included in the reference list they should follow the standard reference style of the journal and should include a substitution of the publication date with either "Unpublished results" or "Personal communication" Citation of a reference as "in press" implies that the item has been accepted for publication.
Web references
As a minimum, the full URL should be given and the date when the reference was last accessed. Any further information, if known (DOI, author names, dates, reference to a source publication, etc.), should also be given. Web references can be listed separately (e.g., after the reference list) under a different heading if desired, or can be included in the reference list.
References in a special issue
Please ensure that the words 'this issue' are added to any references in the list (and any citations in the text) to other articles in the same Special Issue.
Reference style
Text: All citations in the text should refer to:
1. Single author: the author's name (without initials, unless there is ambiguity) and the year of publication;
2. Two authors: both authors' names and the year of publication;
3. Three or more authors: first author's name followed by "et al." and the year of publication.
Citations may be made directly (or parenthetically). Groups of references should be listed first alphabetically, then chronologically.
Examples: "as demonstrated (Allan, 1996a, 1996b, 1999; Allan and Jones, 1995). Kramer et al. (2000) have recently shown ...."
List: References should be arranged first alphabetically and then further sorted chronologically if necessary. More than one reference from the same author(s) in the same year must be identified by the letters "a", "b", "c", etc., placed after the year of publication.
Examples:
Reference to a journal publication:
Van der Geer, J., Hanraads, J.A.J., Lupton, R.A., 2000. The art of writing a scientific article. J. Sci. Commun. 163, 51–59.
Reference to a book:
Strunk Jr., W., White, E.B., 1979. The Elements of Style, third ed. Macmillan, New York.
Reference to a chapter in an edited book:
Mettam, G.R., Adams, L.B., 1999. How to prepare an electronic version of your article, in: Jones, B.S., Smith , R.Z. (Eds.), Introduction to the Electronic Age. E-Publishing Inc., New York, pp. 281–304.
Developmental Biology's reference style is also available from EndNote.
Journal abbreviations source
Journal names should be abbreviated according to
Index Medicus journal abbreviations: http://www.nlm.nih.gov/tsd/serials/lji.html;
List of serial title word abbreviations: http://www.issn.org/2-22661-LTWA-online.php;
CAS (Chemical Abstracts Service): http://www.cas.org/sent.html.
Video data
Elsevier accepts video material and animation sequences to support and enhance your scientific research. Authors who have video or animation files that they wish to submit with their article are strongly encouraged to include these within the body of the article. This can be done in the same way as a figure or table by referring to the video or animation content and noting in the body text where it should be placed. All submitted files should be properly labeled so that they directly relate to the video file's content. In order to ensure that your video or animation material is directly usable, please provide the files in one of our recommended file formats with a maximum size of 10 MB. Video and animation files supplied will be published online in the electronic version of your article in Elsevier Web products, including ScienceDirect: http://www.sciencedirect.com. Please supply 'stills' with your files: you can choose any frame from the video or animation or make a separate image. These will be used instead of standard icons and will personalize the link to your video data. For more detailed instructions please visit our video instruction pages at http://www.elsevier.com/artworkinstructions. Note: since video and animation cannot be embedded in the print version of the journal, please provide text for both the electronic and the print version for the portions of the article that refer to this content.
Supplementary data
Elsevier accepts electronic supplementary material to support and enhance your scientific research. Supplementary files offer the author additional possibilities to publish supporting applications, high-resolution images, background datasets, sound clips and more. Supplementary files supplied will be published online alongside the electronic version of your article in Elsevier Web products, including ScienceDirect: http://www.sciencedirect.com. In order to ensure that your submitted material is directly usable, please provide the data in one of our recommended file formats. Authors should submit the material in electronic format together with the article and supply a concise and descriptive caption for each file. For more detailed instructions please visit our artwork instruction pages at http://www.elsevier.com/artworkinstructions.
Submission checklist
It is hoped that this list will be useful during the final checking of an article prior to sending it to the journal's Editor for review. Please consult this Guide for Authors for further details of any item.
Ensure that the following items are present:
One Author designated as corresponding Author:
• E-mail address
• Full postal address
• Telephone and fax numbers
All necessary files have been uploaded
• Keywords
• All figure captions
• All tables (including title, description, footnotes)
Further considerations
• Manuscript has been "spellchecked" and "grammar-checked"
• References are in the correct format for this journal
• All references mentioned in the Reference list are cited in the text, and vice versa
• Permission has been obtained for use of copyrighted material from other sources (including the Web)
• Color figures are clearly marked as being intended for color reproduction on the Web (free of charge) and in print or to be reproduced in color on the Web (free of charge) and in black-and-white in print
• If only color on the Web is required, black and white versions of the figures are also supplied for printing purposes
For any further information please visit our customer support site at http://epsupport.elsevier.com.
Use of the Digital Object Identifier
The Digital Object Identifier (DOI) may be used to cite and link to electronic documents. The DOI consists of a unique alpha-numeric character string which is assigned to a document by the publisher upon the initial electronic publication. The assigned DOI never changes. Therefore, it is an ideal medium for citing a document, particularly 'Articles in press' because they have not yet received their full bibliographic information. The correct format for citing a DOI is shown as follows (example taken from a document in the journal Physics Letters B):
doi:10.1016/j.physletb.2003.10.071
When you use the DOI to create URL hyperlinks to documents on the web, they are guaranteed never to change.
Proofs
One set of page proofs (as PDF files) will be sent by e-mail to the corresponding author (if we do not have an e-mail address then paper proofs will be sent by post) or, a link will be provided in the e-mail so that authors can download the files themselves. Elsevier now provides authors with PDF proofs which can be annotated; for this you will need to download Adobe Reader version 7 (or higher) available free from http://www.adobe.com/products/acrobat/readstep2.html. Instructions on how to annotate PDF files will accompany the proofs (also given online). The exact system requirements are given at the Adobe site: http://www.adobe.com/products/acrobat/acrrsystemreqs.html#70win.
If you do not wish to use the PDF annotations function, you may list the corrections (including replies to the Query Form) and return them to Elsevier in an e-mail. Please list your corrections quoting line number. If, for any reason, this is not possible, then mark the corrections and any other comments (including replies to the Query Form) on a printout of your proof and return by fax, or scan the pages and e-mail, or by post. Please use this proof only for checking the typesetting, editing, completeness and correctness of the text, tables and figures. Significant changes to the article as accepted for publication will only be considered at this stage with permission from the Editor. We will do everything possible to get your article published quickly and accurately. Therefore, it is important to ensure that all of your corrections are sent back to us in one communication: please check carefully before replying, as inclusion of any subsequent corrections cannot be guaranteed. Proofreading is solely your responsibility. Note that Elsevier may proceed with the publication of your article if no response is received.
Offprints
The corresponding author, at no cost, will be provided with a PDF file of the article via e-mail. For an extra charge, paper offprints can be ordered via the offprint order form which is sent once the article is accepted for publication. The PDF file is a watermarked version of the published article and includes a cover sheet with the journal cover image and a disclaimer outlining the terms and conditions of use.
Distribution of Material
Authors who publish a research article in Developmental Biology must be prepared to freely distribute to academic researchers for their own use any cell lines, DNA clones, monoclonal antibodies, or genetically engineered mice described in the article. All genetic-sequence information published in Developmental Biology must also be deposited with GenBank or the EMBL Database Library.
For inquiries relating to the submission of articles (including electronic submission where available) please visit this journal's homepage. You can track accepted articles at http://www.elsevier.com/trackarticle and set up e-mail alerts to inform you of when an article's status has changed. Also accessible from here is information on copyright, frequently asked questions and more. Contact details for questions arising after acceptance of an article, especially those relating to proofs, will be provided by the publisher.
Editorial Board
Editor-in-Chief:
R. Krumlauf
| Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA, Fax: +1 816 926 2008, Tel: +1 816 926 4051, Email: rek@stowers-institute.org |
Genomes and Developmental Control Editors:
E.H. Davidson
| Div. of Biology, 156-29, California Institute of Technology, 1201 E California Blvd, Pasadena, CA 91125-0001, USA, Fax: +1 626 793 3047, Tel: +1 626 395 4937 /4933 lab, Email: davidson@caltech.edu |
M.S. Levine
| Dept. of Chemistry and Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720-1460, USA, Fax: +1 510 643 5785, Tel: +1 510 642 5014, Email: mlevine@berkeley.edu |
Evolution of Developmental Control Mechanisms Editors:
M. Bronner-Fraser
| Div. of Biology, 139-74, California Institute of Technology, 1200 E. California Blvd., Pasadena, CA 91125, USA, Fax: +1 626 395 7717, Tel: +1 626 395 3355 |
E.H. Davidson
| Div. of Biology, 156-29, California Institute of Technology, 1201 E California Blvd, Pasadena, CA 91125-0001, USA, Fax: +1 626 793 3047, Tel: +1 626 395 4937 /4933 lab |
C. Desplan
| Dept. of Biology, New York University, 100 Washington Sq E, New York, NY 10003, USA, Fax: +1 (212) 995-4204, Tel: +1 (212) 998-8218 |
M. Shankland
| Inst. of Cellular and Molecular Biology, University of Texas at Austin, 1 University Station C1000, Austin, TX 78712, USA, Fax: +1512 471 3878, Tel: +1 512 232-1892 |
Editors:
C. Birchmeier
| Abt. für Medizinische Genetik, Max-Delbrück-Zentrum Berlin (MDZ), Robert-Roessle-Str. 10, 13122 Berlin, Germany, Fax: +49 30 94063765, Tel: +49 30 94062403, Email: cbirch@mdc-berlin.de |
M. Bronner-Fraser
| Div. of Biology, 139-74, California Institute of Technology, 1200 E. California Blvd., Pasadena, CA 91125, USA, Fax: +1 626 395 7717, Tel: +1 626 395 3355, Email: mbronner@caltech.edu |
S. Cohen
| Temasek Life Sciences Lab. (TLL), National University of Singapore (NUS), 1 Research Link, 117604 Singapore, Singapore, Tel: +65 6872 7010, Email: cohen@tll.org.sg |
E.H. Davidson
| Div. of Biology, 156-29, California Institute of Technology, 1201 E California Blvd, Pasadena, CA 91125-0001, USA, Fax: +1 626 793 3047, Tel: +1 626 395 4937 /4933 lab, Email: davidson@caltech.edu |
C. Desplan
| Dept. of Biology, New York University, 100 Washington Sq E, New York, NY 10003, USA, Fax: +1 (212) 995-4204, Tel: +1 (212) 998-8218, Email: cd38@nyu.edu |
S.E. Fraser
| Biological Imaging Center, 139-74, California Institute of Technology, 1200 East California Blvd, Pasadena, CA 91125, USA, Fax: +1 626 449-5163, Tel: +1 626 395-2790, Email: sefraser@caltech.edu |
M. Freeman
| Lab. of Molecular Biology, Div. of Cell Biology, Medical Research Council (MRC), Hills Road, Cambridge, CB2 0QH, UK, Fax: +44-1223-412142, Tel: +44-1223-402351, Email: devbiol@mrc-lmb.cam.ac.uk |
R. Harland
| Dept. of Chemistry and Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720-1460, USA, Fax: +1 510 643 1729, Tel: +1 510 643 6003, Email: harland@berkeley.edu |
M.S. Levine
| Dept. of Chemistry and Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720-1460, USA, Fax: +1 510 643 5785, Tel: +1 510 642 5014, Email: mlevine@berkeley.edu |
S.E. Mango
| Dept. of Molecular and Cellular Biology, Harvard University, 16 Divinity Avenue, Cambridge, MA 2138, USA, Tel: (617) 496-7201, Email: smango@mcb.harvard.edu |
N. Rajewsky
| Systems Biology of Gene Regulatory Elements, Max-Delbrück-Zentrum Berlin (MDZ), Robert-Rössle-Str. 10, 13125 Berlin, Germany, Fax: +49- 30 - 94 06 306 45, Tel: +49- 30 - 94 06 29 99, Email: rajewsky@mdc-berlin.de |
G.B. Ruvkun
| Dept. of Molecular Biology, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA, Fax: +1 617 726 68 93, Tel: +1 617 726 5959, Email: ruvkun@molbio.mgh.harvard.edu |
M. Shankland
| Inst. of Cellular and Molecular Biology, University of Texas at Austin, 1 University Station C1000, Austin, TX 78712, USA, Fax: +1512 471 3878, Tel: +1 512 232-1892, Email: hastypig@mail.utexas.edu |
P. Soriano
| Dept. of Developmental and Regenerative Biology, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029-6574, USA, Fax: +1 (212) 860-9279, Tel: +1 (212) 241-4552, Email: philippe.soriano@mssm.edu |
S. Dietrich
| London Bridge, London, UK |
R.P. Harvey
| Darlinghurst, NSW, Australia |
C. Marcelle
| Marseille Cedex 09, France |
P. Tam
| Wentworthville, NSW, Australia |
|
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