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期刊名称:CYTOMETRY PART A

ISSN:1552-4922
版本:SCI-CDE
出版频率:Monthly
出版社:WILEY, 111 RIVER ST, HOBOKEN, USA, NJ, 07030-5774
  出版社网址:http://www3.interscience.wiley.com/cgi-bin/home
期刊网址:http://www3.interscience.wiley.com/cgi-bin/jhome/33945
影响因子:4.355
主题范畴:BIOCHEMICAL RESEARCH METHODS;    CELL BIOLOGY

期刊简介(About the journal)    投稿须知(Instructions to Authors)    编辑部信息(Editorial Board)   



About the journal

 

Cover Image
Aims and Scope

Cytometry Part A embraces all aspects of analytical cytology and cytomics including flow cytometry, image cytometry, bead-based array analyses, slide-based array analyses, as well as other cell-based spectroscopic analyses. The research featured in the journal encompasses not only the development of the techniques and reagents needed to measure cell features and cellular constituents (molecules), but also investigations that primarily employ these techniques for characterization in order to provide an understanding of function and regulation in the context of the cell, organ, and organism. Cytometry publishes original research articles, in-depth reviews, rapid communications of new, novel "hot" topics, and technical innovation articles.


Instructions to Authors

Editorial Policy

Cytometry is the Official Journal of the International Society for Analytical Cytology. Clinical Cytometry is an Official Publication of the Clinical Cytometry Society and The International Society for Analytical Cytology

The scope of Cytometry embraces all aspects of analytical cytology, which is defined broadly as characterization and measurement of cells and cellular constitutents for biological, diagnostic, and therapeutic purposes. It includes components of cytochemistry, cytophysics, cell biology, molecular biology, physiology, pathology, image analysis, statistics, instrumentation, clinical laboratory practice, and other relevant subjects. Manuscripts may include new experimental results, descriptions of new methods or modifications of existing ones, or new interpretations of previously published data.

Manuscripts from all countries are invited but must be in English. Authors in Japan please note: Wiley-Japan can provide authors in Japan with a list of recommended services to check and improve the English in their papers BEFORE SUBMISSION. Please contact Masayo Kobayashi in the Wiley-Japan office by fax: 81 3 3556 9763 or E-mail: wileyjpn@mb.kom.ne.jp for more information.

Authors are not required to be members of the International Society for Analytical Cytology.

Review of Manuscripts
An expert and anonymous reviewing process is important in assessing the scientific soundness of contributions to Cytometry and frequently helps authors to present their findings clearly and concisely. The Editorial Board of Cytometry selects reviewers, assists in review of manuscripts, makes recommendations concerning the suitability of manuscripts for publication, and advises the Editor on matters related to publication policy. All manuscripts will be evaluated independently by two reviewers. Reviewers are requested to submit written evaluations employing the following criteria:

1. Does the subject matter fall within the scope of Cytometry?
2. Does the paper describe original findings and add significantly to knowledge in its field?
3. Are the aims, results, and discussion presented clearly and concisely?
4. Are the experimental methods generally acceptable and are they described in sufficient detail to permit repetition of the work?
5. Is the documentation of the findings adequate?
6. Are the illustrations appropriate and of acceptable quality?
7. Are quantitative results statistically supported?
8. Is the list of references current and complete?

The Editor-in-Chief, on the basis of recommendations from the reviewers and the Editorial Board, may accept the manuscript, decline it, return it for revision, or send it to a third reviewer to referee differences of opinion between the initial reviewers.

Forms of Publication.
Cytometry publishes five types of contributed papers:

Articles are full-length reports of original research in all fields of analytical cytology. The investigation may contribute to the development, evaluation, or application of cytometric methods and their use in biology and medicine.

Reviews are comprehensive appraisals of current cytometric issues and advances. They are subject to the same review process as other papers. Reviews are welcomed, but authors should consult the Editor-in-Chief about the suitability of a proposed Review before its preparation.

Technical Notes briefly describe improvements or helpful modifications in procedures for cytometric and related techniques. The Technical Note should include a brief statement of purpose, an adequately detailed description of the procedure, a statement of expected results, and references to pertinent literature. Observations based on the application of the method also may be included.

Rapid Communications are original articles of such timeliness and interest that they merit priority processing. Authors should submit their manuscript with a letter explaining their reasons for requesting rapid processing. If the Editor agrees with the request, the manuscript will receive an expedited review and, when accepted, priority for publication; otherwise the manuscript will be processed as a regular submission.

Letters to the Editor provide a forum for communication of opinion, interpretation, and new information on scientific/political matters. Letters are judged on appropriateness of the subject and interest to the readers. They should be concise and to the point.

Length of Manuscripts and Page Charges

Authors are reminded that brevity is a virtue and contributes to the clarity of their contribution. Normally, articles will be limited to about 5,000 words and a combined total of six figures and tables. Authors will be asked to shorten excessively verbose manuscripts. Authors of articles that exceed eight printed pages will be charged $150 per excess page. Prior to publication, the Editor may waive this charge for authors who specifically request exemption and who provide appropriate reasons to justify their request.


Manuscript Submission

Authors are strongly encouraged to submit their manuscripts online at http://cyto-wiley.manuscriptcentral.com/.

Authors are encouraged to include the names and addresses of persons outside their own institutions who might be qualified to serve as reviewers. Authors can request their manuscript not be reviewed by reviewers whose opinion, they believe, may be unfavorably biased. Authors may also request their manuscript be transmitted to specific members of the Editorial Board.

Copyright. Submission of a manuscript implies that it has been approved by all the named authors, that it reports unpublished work, and that it is not under consideration for publication elsewhere. If the manuscript is accepted for publication, it will become the sole property of the publisher and will be copyrighted in the name of the publisher. The manuscript, in whole or part, must not be published elsewhere in either English or another language.


Manuscript Preparation

Manuscript Organization

All articles should be double-spaced throughout, with each page numbered consecutively. Begin each section, described below, on a new page.

Title Page:
The opening page must contain: a) complete title (be succinct and informative, avoid subtitles); b) name and affiliations of each author (specific to the department level); c) a running headline, not to exceed 45 characters in length, including spaces; d) complete contact information -- the corresponding author's mailing address, phone and fax numbers and e-mail address; e) credits for research support as a footnote to the title; and f) any important miscellaneous information, e.g., that the research is based on a conference presentation, also as a footnote to the title.

Abstract and Key terms:
Authors are required to provide a structured abstract. The abstract, which should not exceed 200 words, should consist of four paragraphs, labeled: Background, Methods, Results, Conclusions.They should describe, respectively, the reason for the study, how the study was performed, the most important results, and what is concluded from the results. Below the abstract, provide three to ten key words or short phrases for indexing. The subject under investigation and technologies or methods employed must be included. The Medical Subject Headings List from Index Medicus should be used whenever possible.

Introduction:
State the aim of the work and the problem that stimulated it. Briefly summarize relevant published investigations.

Materials and Methods:
Present in sufficient detail to permit the work to be repeated by other investigators.

Results:
Present results concisely, avoiding redundant use of both tables and figures to illustrate the same data set.

Discussion:
Limit to interpretation of results, with a minimum of recapitulation of findings.

References:
Cite references in text and list at the end of the article. Follow the instructions for Literature Cited, below.

Figures, Tables, and their Legends:
Illustrations, tables and legends must be numbered consecutively and cited sequentially in text; design these to be self-explanatory without reference to the text.

General Rules and Style

Spelling:
Cytometry uses Webster's New Collegiate Dictionary as its standard for spelling.

Style:
For information on style, abbreviations, nomenclature, and the preparation of copy, authors are referred to the Council of Biology Editors (CBE) Style Manual 6th edition, available from the Council of Biology Editors, Inc., 11 South La Salle Street, Chicago, IL 60603-1210. Abbreviations and acronyms are spelled out at their first use and abbreviated in parentheses immediately thereafter.

Units:
The units for all Measurements must conform to the International System of Units (SI). If a measurement is made in other units, then the SI equivalent should be given in parentheses.

Products and Companies:
If authors refer to specific products, they must identify the company by citing, in parentheses, the company's name, city, and state or country.

Literature Cited:

Wiley's Journal Styles Are Now in EndNote
EndNote is a software product that we recommend to our journal authors to help simplify and streamline the research process. Using EndNote's bibliographic management tools, you can search bibliographic databases, build and organize your reference collection, and then instantly output your bibliography in any Wiley journal style.
Download Reference Style for this Journal: If you already use EndNote, you can
download the reference style for this journal.
How to Order: To learn more about EndNote, or to purchase your own copy,
click here.
Technical Support: If you need assistance using EndNote, contact
endnote@isiresearchsoft.com, or visit www.endnote.com/support.

References may be made only to published works and papers in press. Work in progress, unpublished experiments, and personal communications are specifically excluded from the reference list but may be acknowledged in parentheses in the text. Citation of references in text must use the Citation-Sequence format in which the reference number is entered in parentheses.
References must be listed sequentially at the end of the maunscript. Abbreviations of journal names must conform to those used in Index Medicus. Authors are responsible for the accuracy of the references. The following formats must be used:

Journal Article
1. Hüller R, Glossner E, Schuab S, Weingärtner J, Kachel V. The macro flow planktometer: a new device for volume and fluorescence analysis in macro plankton including triggered video imaging in flow. Cytometry 1994;17:109-118.

Article in a book or comparable publication
2. Gary JW, Cram LS. Flow karyotyping and chromosome sorting. In: Melamed MR, Lindmo T, Medelsohn ML, editors. Flow cytometry and sorting. 2nd ed. New York: John Wiley & Sons Inc.; 1990. p 503-529.

Books
3. Givan AL. Flow cytometry: first principles. New York: John Wiley & Sons Inc.;1993. 1223 p.

Editorial Office
Requests for copies of the Editorial Policy and Instructions to Contributors, requests for clarification of specific issues, manuscripts submitted for publication, and all other communications with the Editorial Office should be addressed to the Editor-in-Chief:

Charles L. Goolsby, Editor-in-Chief
Northwestern University Medical School
Department of Pathology
303 East Chicago Avenue, Ward Building 6-204
Chicago, IL 60611-3008
Telephone: 312-503-1847
Telefax: 312-503-1848
E-mail: cytometry@nwu.edu

European contributors may address their requests to the European Editor:

Janos Szollosi, Ph.D.
Department of Biophysics and Cell Biology
Medical University,
School of Debreceen,
P.O. Box 39
Nagyer dei krt, 98
Debreceen, Hungary, H-4012
E-mail: szollo@jaguar.dote.hu

Bioimaging contributors may address their requests to the Bioimaging Editor:

Stephen Lockett
NCI-Frederick
Boyle St., Bldg. 1050
Frederick, MD 21702
Telephone: 301-846-5515
E-mail: sjlockett@lbl.gov

Reprints
Reprints are supplied by the publisher at a cost based on the number of pages in the printed article and the number of reprints ordered, as shown on the order blank mailed with the proofs. Wiley is pleased to extend a 50% discount on reprint orders to ISAC and CCS members.


Disk Submission Instructions

Please return your final, revised manuscript on disk as well as hard copy.
The hard copy must match the disk.

The Journal strongly encourages authors to deliver the final, revised version of their accepted manuscripts (text, tables, and, if possible, illustrations) on disk. Given the near-universal use of computer word-processing for manuscript preparation, we anticipate that providing a disk will be convenient for you, and it carries the added advantages of maintaining the integrity of your keystrokes and expediting typesetting. Please return the disk submission slip below with your manuscript and labeled disk(s).

Guidelines for Electronic Submission

Text
Storage medium. 3-1/2" high-density disk in IBM MS-DOS, Windows, or Macintosh format.

Software and format. Microsoft Word 6.0 is preferred, although manuscripts prepared with any other microcomputer word processor are acceptable. Refrain from complex formatting; the Publisher will style your manuscript according to the Journal design specifications. Do not use desktop publishing software such as Aldus PageMaker or Quark XPress. If you prepared your manuscript with one of these programs, export the text to a word processing format. Please make sure your word processing program's "fast save" feature is turned off. Please do not deliver files that contain hidden text: for example, do not use your word processor's automated features to create footnotes or reference lists.

File names. Submit the text and tables of each manuscript as a single file. Name each file with your last name (up to eight letters). Text files should be given the three-letter extension that identifies the file format. Macintosh users should maintain the MS-DOS "eight dot three" file-naming convention.

Labels. Label all disks with your name, the file name, and the word processing program and version used.

Illustrations
All print reproduction requires files for full color images to be in a CMYK color space (not RGB). If possible, ICC or ColorSync profiles of your output device should accompany all digital image submissions.

Storage medium. Submit as separate files from text files, on separate disks or cartridges. If feasible, full color files should be submitted on separate disks from other image files. 3-1/2" high-density disks, CD, Iomega Zip, and 5 1/4" 44- or 88-MB SyQuest cartridges can be submitted. At authors' request, cartridges and disks will be returned after publication.

Software and format. All illustration files should be in TIFF or EPS (with preview) formats. Do not submit native application formats.

Resolution. Journal quality reproduction will require greyscale and color files at resolutions yielding approximately 300 ppi. Bitmapped line art should be submitted at resolutions yielding 600-1200 ppi. These resolutions refer to the output size of the file; if you anticipate that your images will be enlarged or reduced, resolutions should be adjusted accordingly.

File names. Illustration files should be given the 2- or 3-letter extension that identifies the file format used (i.e., .tif, .eps).

Labels. Label all disks and cartridges with your name, the file names, formats, and compression schemes (if any) used. Hard copy output must accompany all files.


Standard Abbreviations for Cytometry

2D
two-dimensional

2-ME
2-mercaptoethanol

3D
three-dimensional

7-AAD
aminoactinomycin D

a.u.
arbitrary unit

Ab
antibody

ABC
antibody binding capacity

ac
alternating current

ADC
analog to digital converter

Ag
antigen

AIDS
acquired immune deficiency syndrome

ALL
acute lymphoblastic leukemia

AMCA
7-amino-4-methylcoumarin-3-acetic acid

AML
acute myeloblastic leukemia

ANN
artificial neural network

APC
allophycocyanin

Ara-C
cytosine arbinoside

ATP
adenosine triphosphate: ADP, AMP, GDP, GMP, GTP, CTP, UDP

BCECF
2,7-bis-(2-carboxyethyl)-5-(and-6)-carboxyfluorescein

bp
base pair

BrdU
bromodeoxyuridine

BSA
bovine serum albumin

CD
cluster of differentiation

CDKs
cyclin dependent kinases

cDNA
complementary DNA

CGH
comparative genomic hybridization

CLL
chronic lymphocytic leukemia

CML
chronic myeloid cytic leukemia

CMV
cytomegalovirus

ConA
concanavalin A

cpm
counts per minute

CSF
colony-stimulating factor

CV
coefficient of variation

DAB
3,3 diaminobenzidin

DAPI
4,6-diamidino-2-phenylindole, dihydrochloride

DC
dendritic cell

dc
direct current

DMEM
Dulbecco's minimum essential medium

DMSO
dimethylsulfoxide

DNA
deoxyribonucleic acid

DNase
deoxyribonuclease

DPH
1,6-diphenyl-1,3,5-hexatriene

ds
double stranded

EB
ethidium bromide

EBV
Epstein-Barr virus

EDTA
ethylene-diaminetetraacetic acid

ELISA
enzyme-linked immunosorbent assay

EM
electron microscopy

ER
endoplasmatic reticulum

EST
expressed sequence tag

FACS
fluorescence-activated cell sorting

FC(B)S
fetal calf (bovine) serum

FCM
flow cytometry

FDA
fluorescein diacetate

FISH
fluorescence in situ hybridization

FITC
fluorescein isothiocyanate

FRET
fluorescence resonance energy transfer

FSC
forward angle scattered light: FLS

FWHM
full width at half maximum

g
gravity

G-CSF
granulocyte colony-stimulating factor

GFP
green fluorescent protein

GM-CSF
granulocyte-macrophage colony-stimulating factor

GSH
glutathione

Hb
hemoglobin

HbF
fetal hemoglobin

HBSS
Hank's balanced salt solution

HEPES
N-2-hydroxyethelpiperazine-N2 ethansulphonic acid

HIV
human immunodeficiency virus

HLA
human leukocyte antigen

HPLC
high performance liquid chromatography

HSA
human serum albumin

i.m.
intramuscular

i.p.
intraperitoneal

i.v.
intravenous

I/O
input/output

IEF
isoelectric focusing

IFN
interferon

Ig
immunoglobulin

IL
interleukin

IMDM
Iscove's modified Dulbecco's medium

IU
international unit

kb
kilobase

kDa
kilodalton

LED
light emitting diode

M
molar

mAb
monoclonal antibody

M-CSF
macrophage CSF

MDR
multidrug resistance

MESF
molecules of equivalent soluble fluorochrome

MFI
mean fluorescence intensity

MHC
major histocompatibility complex

MNC
mononuclear cell

mRNA
messenger ribonucleic acid

MW
molecular weight

n or No
number

NK
cell natural killer cell

NS
not significant

OD
optical density

P
probability

PAGE
polyacrylamide gel electrophoresis

PBL
peripheral blood lymphocyte

PBMC
peripheral blood mononuclear cells

PBS
phosphate-buffered saline

PCR
polymerase chain reaction

PE
phycoerythrin

PEG
polyethylene glycol

PerCP
peridinin chlorophyll protein

PHA
phytohemagglutinin

PI
propidium iodide

PKC
protein kinase C

PMN
polymorphonuclear leukocyte

PMT
photomultiplier

PWM
pokeweed mitogen

RAM
random access memory

Rb
retinoblastoma protein

RBC
red blood cells

RFLP
restriction fragment length polymorphism

RIA
radioimmunoassay

RNA
ribonucleic acid

rpm
revolutions per minute

s.c.
subcutaneous

SAv
streptavidin

SBA
soybean agglutinin

SCF
stem cell factor, kit ligand, Steel factor

SCID
severe combined immunodeficiency

SD
standard deviation

SDS
sodium dodecyl sulfate

SE
standard error

SEM
standard error of the mean

sIg
surface immunoglobulin

ss
single stranded

SSC
side angle scattered light

SV40
Simian virus 40

t?BR>half-life, half-time

TCR
T cell receptor

TdT
terminal deoxynucleotidyl transferase

TNF
tumor necrosis factor

TRITC
tetramethyl rhodamine

TUNEL
terminal dUTP nick end labeling

UV
ultraviolet

vol
volume

WBC
white blood cells

WGA
wheat germ agglutinin

YAC
yeast artificial chromosome


Editorial Board
E d i t o r - i n - C h i e f

Charles L. Goolsby, Ph.D.

Northwestern University Medical School
Department of Pathology
Ward Building 6-204
303 East Chicago Avenue
Chicago, IL 60611-3008
Telephone: 312-503-1847
Telefax: 312-503-1848
E-mail: cytometry@nwu.edu

Reviews Editor

James Jacobberger
Ralph Durand
European Editor

Janos Szollosi
Bioimaging Editor

Stephen Lockett

A s s o c i a t e   E d i t o r s

David Galbraith
David Hedley
James Jacobberger
James Jett
William Karpus
Paul Smith
Attila Tárnok
Nicholas Terry
Gunter Valet
E d i t o r i a l   B o a r d

Nigel P. Carter
Cambridge, United Kingdom

Kenneth Castleman
League City, Texas

L. Scott Cram
Los Alamos, New Mexico

Harry A. Crissman
Los Alamos, New Mexico

Zbigniew Darzynkiewicz
Hawthorne, New York

Caroline Dive
Manchester, United Kingdom

Walter Giaretti
Genoa, Italy

Jonathan Kagan
Rockville, Maryland

Keiji Kawamoto
Osaka, Japan

Ruth Knuechel-Clarke
Regensburg, Germany

Awtar Krishan
Miami, Florida

James Leary
Galveston, Texas

John Lehman
Albany, New York

Katharine A. Muirhead
Malvern, Pennsylvania


Jose-Enrique O'Connor
Valencia, Spain

Michael G. Ormerod
Reigate, United Kingdom

Maria Pallavicini
San Francisco, California

Peter S. Rabinovitch
Seattle, Washington

Frans C.S. Ramaekers
Maastricht, The Netherlands

Mario Roederer
Bethesda, Maryland

Kohsuke Sasaki
Yamaguchi, Japan

Larry Sklar
Albuquerque, New Mexico

Harald B. Steen
Oslo, Norway

Hans Tanke
Leiden, The Netherlands

Frank Traganos
Hawthorne, New York

Yves Usson
La Tronche, France

Lucas van Vliet
Delft, The Netherlands

R. Allen White
Houston, Texas


E d i t o r i a l   O f f i c e

Joy Holliday
E-mail: cytometry@nwu.edu


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