期刊名称：BIOORGANIC CHEMISTRY
 期刊简介(About the journal)
投稿须知(Instructions to Authors)
编辑部信息(Editorial Board)
About the journal
|
Publishing original research at the interface of chemistry and biology, Bioorganic Chemistry presents articles where the principles and techniques of organic and physical organic chemistry are used to solve problems of relevance to biology or that describe chemical studies inspired by some biological observation. The emphasis is on chemical or molecular approaches to the solution of important biological problems. Regular articles, review articles, and preliminary communications are included.
Research Areas Include:
Achievement of useful organic transformations by the application of enzymes
Application of kinetic, isotopic, stereochemical, and spectral techniques to the study of enzymes and metabolic pathways
Characterization of the chemistry involved in new enzymatic reactions and metabolic pathways
Chemical modifications of nucleic acids and manipulation of genetic material with modified nucleic acids
Description of new chemistry that results from findings in biology
Determination of the molecular basis of hormone and drug action
Development of catalyst systems that mimic enzymes and coenzymes
Development of mechanism-based and active site-directed inhibitors for enzymes and characterization of the associated chemistry
Elucidation of enzyme mechanisms and structure
Elucidation of the principles involved in receptor site recognition
Investigation of the structure and mechanism of action of pheromones and other chemical communicants
Investigations of chemical model systems for enzymes, peptides, and other biological molecules
Studies on coenzyme structure and reactivity
Elsevier also publishes books in this area. If you have a suggestion for a book topic or would like to submit a new book proposal, please contact us at:
|
 |
Instructions to Authors
1. Aims and Scope
Bioorganic Chemistry publishes accounts of research that are at the interface of chemistry and biology. The guiding principle that the Editorial Board will follow in accepting manuscripts for publication is that the research either uses the principles and techniques of organic and physical organic chemistry in attempting to solve some problem of relevance to biology or describes chemical studies that are inspired by some biological observation. Within this context, manuscripts suitable for submission are ones that deal with such topics as enzymology, enzyme models, biosynthesis and combinatorial biosynthesis, biomimetic synthesis, molecular recognition, protein and peptide chemistry, nucleic acid chemistry (including ribozymes and antisense strategies), immunology (including catalytic antibodies), biosensors, the design and synthesis of therapeutics, proteomics, and genomics. In addition, the theoretical treatment of any of these topics is appropriate, as is the application of biophysical techniques to advance our understanding of one of these topics.
Although the journal will be devoted primarily to the publication of Regular Articles, Preliminary Communications, Reviews, and Minireviews will also be published. A Correspondence section may appear periodically as warranted.
Regular Articles must feature novel, previously unpublished material or represent full accounts of findings published earlier in preliminary form.
Preliminary Communications will receive accelerated publication and should describe particularly novel and significant new findings. They should be accompanied by a brief abstract and should not exceed 5 printed pages in length (approximately 3000 words), including references, tables, and figures.
Minireviews and Reviews may embrace the results of various workers in a given area or may feature recent developments from the author's own laboratory. A review that is distinguished by a novel interpretation or representation of earlier findings is especially suitable. The Editor welcomes inquiries concerning the suitability of a particular topic for a review article.
Letters to the Editor offering interpretations of data that are different from those published by other authors will be entertained and, along with the original authors' rebuttal, will be considered for inclusion in the Correspondence section. It is hoped that this section will offer a forum where points of contention concerning various topics of interest to the field of bioorganic chemistry can be discussed in print. From time to time this section will also include announcements and summaries of meetings that are of interest to bioorganic chemists.
2. Submission of Manuscripts
2.1. General
Authors are encouraged to submit manuscripts in electronic format according to the submission instructions given below (Section 2.2). Submissions by mail will also be accepted. Manuscripts must be written in English and should be accompanied by a letter outlining the basic findings of the paper and their significance as well as the names and addresses (postal and e-mail) of 4-6 potential reviewers. It is essential to give a fax number and e-mail address for the corresponding author when submitting a manuscript.
Submission of an article implies that the work described has not been published previously (except in the form of an abstract or as part of a published lecture or academic thesis), that it is not under consideration for publication elsewhere, that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was carried out, and that, if accepted, it will not be published elsewhere in the same form, in English or in any other language, without the written consent of the Publisher.
Upon acceptance of an article, authors will be asked to transfer copyright (for more information on copyright, see http://authors.elsevier.com). This transfer will ensure the widest possible dissemination of information. An e-mail will be sent to the corresponding author confirming receipt of the manuscript. A form facilitating transfer of copyright will be provided. If excerpts from other copyrighted works are included, the author(s) must obtain written permission from the copyright owners and credit the source(s) in the article. Elsevier has preprinted forms for use by authors in these cases: contact ES Global Rights Department, P.O. Box 800, Oxford OX5 1DX, UK; phone: (+44) 1865 843830, fax: (+44) 1865 853333, e-mail: permissions@elsevier.com.
Articles and any other material published in Bioorganic Chemistry represent the opinions of the author(s) and should not be construed to reflect the opinions of the Editor and the Publisher.
There are no submission fees or page charges for papers published in Bioorganic Chemistry.
2.2. Submission of manuscripts prior to acceptance
Manuscripts should be addressed to:
Bioorganic Chemistry
Editorial Office
525 B Street, Suite 1900
San Diego, CA 92101-4495, USA
Tel: (619) 699-6508
Fax: (619) 699-6700
E-mail: boc@elsevier.com
2.2.1. Submission by e-mail
Authors are encouraged to send an electronic version of their article by e-mail to the address given above. This electronic version will be used for the reviewing process. Authors, reviewers, and editors send and receive all correspondence by e-mail and no paper correspondence is necessary.
Note: Electronic articles submitted for the review process may need to be edited after acceptance to follow journal standards. For this an "editable" file format is necessary. See Section 2.3 and the further general instructions on how to prepare your article below.
2.2.2. Submission by post
If manuscripts are submitted by post, four copies (one original and three photocopies) of the manuscript, including one set of high-quality original illustrations suitable for direct reproduction, are required. (Copies of the illustrations are acceptable for the other sets of manuscripts, as long as the quality permits refereeing.)
2.3. Electronic format requirements for accepted articles
2.3.1. General points
We accept most word-processing formats, but Word, WordPerfect, or LaTeX is preferred. An electronic version of the text should be submitted together with the final hard copy of the manuscript. The electronic version must match the hard copy exactly. Always keep a backup copy of the electronic file for reference and safety. Label storage media with your name, journal title, and software used. Save your files using the default extension of the program used. No changes to the accepted version are permissible without the explicit approval of the Editor. Electronic files can be stored on 3?-inch diskette, ZIP disk, or CD (either MS-DOS or Macintosh).
2.3.2. Word processor documents
It is important that the file be saved in the native format of the word processor used. The text should be in single-column format. Keep the layout of the text as simple as possible. Most formatting codes will be removed and replaced on processing the article. In particular, do not use the word processor's options to justify text or to hyphenate words. However, do use bold face, italics, subscripts, superscripts, etc. Do not embed "graphically designed" equations or tables, but prepare these using the word processor's facility. When preparing tables, if you are using a table grid, use only one grid for each individual table and not a grid for each row. If no grid is used, use tabs, not spaces, to align columns. The electronic text should be prepared in a way very similar to that of conventional manuscripts (see also the Author Gateway's Quick guide at http://authors.elsevier.com). Do not import the figures into the text file but, instead, indicate their approximate locations directly in the electronic text and on the manuscript. See also the section on preparation of electronic illustrations. To avoid unnecessary errors, you are strongly advised to use the "spell checker" function of your word processor.
2.3.3. LaTeX documents
If the LaTeX file is suitable, proofs will be produced without rekeying the text. The article should preferably be written using Elsevier Science's document class 'elsart', or alternatively the standard document class 'article'. The Elsevier LaTeX package (including detailed instructions for LaTeX preparation) can be obtained from the Author Gateway's Quick guide at http://authors.elsevier.com. It consists of the files elsart.cls (use this file if you are using LaTeX2e, the current version of LaTeX), elsart.sty and elsart12.sty (use these two files if you are using LaTeX2.09, the previous version of LaTeX), guidelines for users of elsart, a template file for quick start, and the instruction booklet "Preparing Articles with LaTeX."
Although Elsevier can process most word processor file formats, should your electronic file prove to be unusable, the article will be typeset from the hard-copy printout.
3. Preparation of Manuscripts
Manuscripts should be written in good English (American or British usage is accepted but not a mixture of these). Use decimal points (not commas). Manuscripts should be double-spaced throughout on one side of 8.5 x 11-inch or A4 white paper. Ensure that each new paragraph is clearly indicated. Present tables and figure legends on separate pages at the end of the manuscript. If possible, consult a recent issue of the journal to become familiar with layout and conventions. Pages should be numbered consecutively and organized as follows:
The Title Page (p. 1) should contain (in the order given):
1. the article title: Concise and informative. Avoid abbreviations and formulas where possible
2. authors' names and complete affiliations: Where the family name may be ambiguous (e.g., a double name), please indicate this clearly. Present the authors' affiliation addresses (where the actual work was done) below the names. Indicate all affiliations with a lowercase superscript letter immediately after the author's name and in front of the appropriate address. Provide the full postal address of each affiliation, including the country name and, if available, the e-mail addresses of each author. If an author has moved since the work described in the article was done or was visiting at the time, a "present address" (or "permanent address") may be indicated as a footnote to that author's name. The address at which the author actually did the work must be retained as the main affiliation address. Superscript Arabic numerals are used for such footnotes.
3. footnotes to the title
4. the address for manuscript correspondence: The author who is willing to handle correspondence at all stages of refereeing and publication, and also postpublication, should be clearly indicated. Ensure that telephone and fax numbers (with country and area code) are provided in addition to the e-mail address and the complete postal address.
The Abstract (p. 2) must be a single paragraph that summarizes the main findings of the paper in less than 150 words. After the abstract a list of up to 10 keywords that will be useful for indexing or searching should be included. References should be avoided, but if essential, they must be cited in full, without reference to the reference list. Nonstandard or uncommon abbreviations should be avoided, but if essential they must be defined at their first mention in the abstract itself.
The Introduction should be as concise as possible, without subheadings. State the objectives of the work and provide an adequate background, avoiding a detailed literature survey or a summary of the results.
Materials and methods should be sufficiently detailed to enable the experiments to be reproduced. Authors should draw attention to any particular chemical or biological hazards that may be involved in carrying out the experiments described. Any relevant safety precautions should be described; if an accepted code of practice has been followed, a reference to the relevant standards should be given and only relevant modifications should be described.
Results and Discussion may be combined if appropriate and may be organized into subheadings.
The Conclusion may be presented in a short section that may stand alone or form a subsection of a Discussion or Results and Discussion section.
Acknowledgments should be brief and placed before the references, in a separate section, and not as a footnote on the title page. This section should include information on grants received.
References to the literature should be cited by number in square brackets in the text and listed in numerical order at the end. Use the most recent edition of the Chemical Abstracts Service Source Index for abbreviations of journal titles. Please note the following examples:
[1] S. Han, R.A. Moore, R. Viola, Biorg. Chem. 30 (2002) 81-94.
[2] P.R. Ortiz de Montellano, Cytochrome P450: Structure, Mechanism, and Biochemistry, Plenum, New York, 1995.
[3] R.E. Dickerson, R. Timkovich, in: P.D. Boyer (Ed.), The Enzymes, Vol. XI, Academic Press, New York, 1975, pp. 397-500.
Figure legends, tables, figures, and schemes. Present these, in this order, at the end of the article. They are described in more detail below. If you are working with LaTeX and have such features embedded in the text, these can be left, but such embedding should not be done specifically for publishing purposes. Further, high-resolution graphics files must be provided separately (see Preparation of illustrations).
Legends: Ensure that each illustration has a legend. Supply legends on a separate sheet, not attached to the figure. A legend should comprise a brief title (not on the figure itself) and a description of the illustration. Keep text in the illustrations themselves to a minimum but explain all symbols and abbreviations used.
Tables: Tables should be numbered consecutively with Arabic numerals in order of appearance in the text. Place footnotes to tables below the table body and indicate them with superscript lowercase letters. Avoid vertical rules. Be sparing in the use of tables and ensure that the data presented in tables do not duplicate results described elsewhere in the article. Authors should submit complex tables as camera-ready copy.
Text graphics: Present incidental graphics not suitable for mention as figures, plates, or schemes at the end of the article and number them "Graphic 1," etc. Their precise position in the text can then be defined similarly (both on the manuscript and in the file).
Figures and schemes: Figures and schemes should be numbered consecutively with Arabic numerals according to their appearance in the main text. Any lettering (symbols, numbers, etc.) on the illustration should be used in a consistent manner and be of consistent size.
Footnotes. Footnotes should be designated in text by superscript numbers and listed on a separate sheet, starting with the title; in tables they should be noted by superscript letters and placed at the bottom of the page containing the table.
4. Preparation of Illustrations
4.1. Preparation of electronic illustrations
Submitting your artwork in an electronic format helps us to produce your work to the best possible standards, ensuring accuracy, clarity, and a high level of detail.
4.1.1. General points
Always supply high-quality printouts of your artwork, in case conversion of the electronic artwork is problematic.
Make sure you use uniform lettering and sizing of your original artwork.
Save text in illustrations as "graphics" or enclose the font.
Only use the following fonts in your illustrations: Arial, Courier, Helvetica, Times, Symbol.
Number the illustrations according to their sequence in the text.
Use a logical naming convention for your artwork files, and supply a separate listing of the files and the software used.
Provide all illustrations as separate files and as hard-copy printouts on separate sheets.
Provide legends to illustrations separately.
Produce images near to the desired size of the printed version.
A detailed guide on electronic artwork is available on our Web site at http://authors.elsevier.com/artwork. You are urged to visit this site; some excerpts from the detailed information are given here.
4.1.2. Formats
Regardless of the application used, when your electronic artwork is finalized, please "save as" or convert the images to one of the following formats. (Note the resolution requirements for line drawings, halftones, and line/halftone combinations given below.)
EPS: Vector drawings. Embed the font or save the text as "graphics."
TIFF: Color or grayscale photographs (halftones): Always use a minimum of 300 dpi. For color images always use CMYK.
TIFF: Bitmapped line drawings: Use a minimum of 1000 dpi.
TIFF: Combinations bitmapped line/halftone (color or grayscale): A minimum of 500 dpi is required.
DOC, XLS, or PPT: If your electronic artwork is created in any of these Microsoft Office applications, please supply "as is."
Please do not:
Supply embedded graphics in your word processor (spreadsheet, presentation) document.
Supply files that are optimized for screen use (such as GIF, BMP, PICT, WPG); the resolution is too low.
Supply files that are too low in resolution.
Submit graphics that are disproportionately large for the content.
4.2. Preparation of nonelectronic illustrations
Provide all illustrations as high-quality printouts, suitable for reproduction (which may include reduction) without retouching. Number illustrations consecutively in the order in which they are referred to in the text. They should accompany the manuscript, but should not be included within the text. Clearly mark all illustrations on the back (or-in case of line drawings-on the lower front side) with the figure number and the author's name and, in cases of ambiguity, the correct orientation.
4.2.1. Line drawings
Supply high-quality printouts on white paper produced with black ink. The lettering and symbols, as well as other details, should have proportionate dimensions, so as not to become illegible or unclear after possible reduction; in general, the figures should be designed for a reduction factor of 2 to 3. The typesetter will determine the degree of reduction. Illustrations will not be enlarged. Consider the page format of the journal when designing the illustrations.
Photocopies are not suitable for reproduction. Do not use any type of shading on computer-generated illustrations.
4.2.2. Photographs (halftones)
Please supply original photographs for reproduction, printed on glossy paper, very sharp and with good contrast. Remove nonessential areas of a photograph. Do not mount photographs unless they form part of a composite figure. Where necessary, insert a scale bar in the illustration (not below it), as opposed to giving a magnification factor in the legend. Note that photocopies of photographs are not acceptable.
4.2.3. Color illustrations
One piece of color art per article will be published free of charge. Mounted color figures must be submitted on paper or flexible board due to the nature of the reproduction process. Submit color illustrations as original photographs, high-quality computer prints, or transparencies, close to the size expected in publication, or as 35-mm slides. Polaroid color prints are not suitable. Further information concerning color illustrations and costs is available from Author Support (authorsupport@elsevier.ie)
5. Proofs
One set of page proofs in PDF format will be sent by e-mail to the corresponding author and should be returned with corrections as quickly as possible, normally within 2 business days of receipt of the proofs. Should there be no corrections, please confirm this. The Publisher reserves the right to proceed with publication if corrections are not communicated.
Elsevier will do everything possible to publish your article as quickly and accurately as possible. To do this, we need your help. It is important to ensure that all corrections are returned in one communication and are complete, as subsequent corrections will not be possible. Please note that this does not mean that you have any less time to make your corrections, just that only one set of corrections will be accepted.
6. Reprints
Twenty-five reprints will be provided to the corresponding author free of charge. Additional reprints may be ordered.
7. Further information
All questions arising after acceptance of a paper, especially those concerning proofs, should be directed to:
Elsevier
Issue Management
Bioorganic Chemistry
525 B Street, Suite 1900
San Diego, CA 92101-4495, USA
E-mail: t.hermann@elsevier.com
For inquiries relating to the status of accepted articles, please visit http://www.elsevier.com/locate/authors.
Editorial Board
|
Editor:
|
|
C.P. Whitman, Medicinal Chemistry Division, College of Pharmacy PHR 4.220C, The University of Texas, Austin TX 78712
|
|
|
Editorial Board:
|
|
D. Arigoni, Zürich, Switzerland
|
|
|
B. Badet, Centre National de la Recherche Scientifique, Gif-sur-Yvette, France
|
T.P. Begley, Cornell University, Ithaca, USA
|
|
S.J. Benkovic, Pennsylvania State University, Pennsylvania, USA
|
|
R. Breslow, Columbia University, New York, USA
|
|
T.C. Bruice, University of California, Santa Barbara, USA
|
|
T.D.H. Bugg, University of Warwick, Coventry, UK
|
|
P.A. Cole, John Hopkins University, School of Medicine, Baltimore, USA
|
|
S.D. Copley, University of Colorado, Boulder, USA
|
|
B.F. Cravatt, The Scripps Research Institute, La Jolla, USA
|
|
D. Dunaway-Mariano, University of New Mexico, Albuquerque, USA
|
M.C. Fitzgerald, Duke University, Durham, USA
|
|
P.A. Frey, University of Wisconsin, Madison, USA
|
|
J. Gerlt, University of Illinois, Urbana, USA
|
|
B.T. Golding, University of Newcastle upon Tyne, UK
|
|
J.T. Groves, Princeton University, Princeton, USA
|
|
D. Hilvert, Eidgenössische Technische Hochschule, Zürich, Switzerland
|
J. Järv, Tartu University, Tartu, Estonia
|
|
E.K. Jaffe, Fox Chase Cancer Center, Philadelphia, USA
|
|
K. Kakinuma, Tokyo Institute of Technology, Tokyo, Japan
|
|
G.L. Kenyon, University of Michigan, Ann Arbor, USA
|
|
S.M. Kerwin, University of Texas at Austin, Austin, USA
|
|
R.H. Kluger, University of Toronto, Toronto, Canada
|
|
J.W. Kozarich, ActivX Biosciences, La Jolla, USA
| Hung-wen (Ben) Liu, University of Texas at Austin, Austin, USA
|
L.W. McLaughlin, Boston College, Chestnut Hill, USA
|
|
S. Mobashery, Wayne State University, Detroit, USA
|
|
J. Nakanishi, Columbia University, New York, USA
|
|
D. O'Hagan, University of St. Andrews, St Andrews, UK
|
|
D. Pei, Ohio State University, Columbus, USA
|
|
J. Rétey, University of Karlsruhe, Germany
|
|
F.M. Raushel, Texas A & M University, College Station, USA
|
J.P. Richard, State University of New York, Buffalo USA
|
|
I. Saito, Kyoto University, Kyoto, Japan
|
|
T. Scanlan, University of California, San Francisco, USA
|
|
A.I. Scott, Texas A & M University, College Station, USA
|
|
M.E. Tanner, University of British Columbia, Vancouver, Canada
|
|
P.A. Tipton, University of Missouri, Columbia, USA
|
|
C.A. Townsend, Johns Hopkins University, Baltimore, USA
|
R.V. Wolfenden, University of North Carolina, Chapel Hill, USA
|
|
R.W. Woodard, University of Michigan, Ann Arbor, USA
|
|
W. van der Donk, University of Illinois, Urbana, USA |
Manuscripts should be addressed to:
Bioorganic Chemistry
Editorial Office
525 B Street, Suite 1900
San Diego, CA 92101-4495, USA
Tel: (619) 699-6508
Fax: (619) 699-6700 | |
| |
|
|
|
刊名字顺( Alphabetical List of Journals):
返回页首 