期刊名称：BMC MEDICAL GENOMICS
 期刊简介(About the journal)
投稿须知(Instructions to Authors)
编辑部信息(Editorial Board)
About the journal
BMC Medical Genomics (ISSN 1755-8794) is an online journal publishing research articles after full peer review. All articles are published, without barriers to access, immediately upon acceptance. The journal is published by BioMed Central Ltd, Floor 6, 236 Gray's Inn Road, London, WC1X 8HB, United Kingdom.
Scope
BMC Medical Genomics is an Open Access, peer-reviewed journal that considers articles on all aspects of functional genomics, genome structure, genome-scale population genetics, epigenomics, proteomics, systems analysis, and pharmacogenomics in relation to human health and disease.
Criteria for publication
Publication of research articles by BMC Medical Genomics is dependent primarily on their validity and coherence, as judged by peer reviewers, who are also asked whether the writing is comprehensible and how interesting they consider the article to be. If an article is of broad interest, the authors may be asked if they would prefer it to be published in BMC Medicine, and the article may be highlighted in a variety of ways as a service to our readers and contributors.
Speed of publication
BMC Medical Genomics offers a very fast publication schedule while maintaining rigorous peer review; all articles must be submitted online, and peer review is managed fully electronically (articles are distributed in PDF form, which is automatically generated from the submitted files). Articles will be published electronically in manuscript form immediately upon acceptance. A fully structured web version, and accompanying laid out PDF, will be published within a few weeks of acceptance.
Flexibility
As an electronic-only journal, BMC Medical Genomics offers authors the opportunity to publish large data sets, large numbers of illustrations and moving pictures, to display data in a form that can be read directly by other software packages so as to allow readers to manipulate the data for themselves, and to create all relevant links (for example, to PubMed, to sequence and other databases, and to other papers).
Submission of manuscripts
Manuscripts must be submitted to BMC Medical Genomics electronically using the online submission system. Full details of how to submit a manuscript are given in the instructions for authors.
Indexing and archiving
Following publication in BMC Medical Genomics, the full text of each article is immediately and permanently archived in PubMed Central, the US National Library of Medicine's full-text repository of life science literature, and also in repositories at the University of Potsdam in Germany, at INIST in France and in e-Depot, the National Library of the Netherlands' digital archive of all electronic publications. BMC Medical Genomics is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, EMBASE, Scopus and Google Scholar.
Instructions to Authors
Preparing main manuscript text
File formats
The following word processor file formats are acceptable for the main manuscript document:
Microsoft Word (version 2 and above)
Rich text format (RTF)
Portable document format (PDF)
TeX/LaTeX (use BioMed Central's TeX template)
DeVice Independent format (DVI)
Publicon Document (NB)
Users of other word processing packages should save or convert their files to RTF before uploading. Many free tools are available which ease this process.
TeX/LaTeX users: We recommend using BioMed Central's TeX template and BibTeX stylefile. If you use this standard format, you can submit your manuscript in TeX format (after you submit your TEX file, you will be prompted to submit your BBL file). If you have used another template for your manuscript, or if you do not wish to use BibTeX, then please submit your manuscript as a DVI file. We do not recommend converting to RTF.
Note that figures must be submitted as separate image files, not as part of the submitted DOC/ PDF/TEX/DVI file.
Article types
When submitting your manuscript, you will be asked to assign one of the following types to your article:
Research article
Case report
Database
Debate
Software
Study protocol
Technical advance
Please read the descriptions of each of the article types, choose which is appropriate for your article and structure it accordingly. If in doubt, your manuscript should be classified as a Research article, the structure for which is described below.
Manuscript sections for Research articles
Manuscripts for Research articles submitted to BMC Medical Genomics should be divided into the following sections:
Title page
Abstract
Background
Methods
Results
Discussion
Conclusions
List of abbreviations used (if any)
Competing interests
Authors' contributions
Authors' information (if any)
Acknowledgements and Funding
References
Figure legends (if any)
Tables and captions (if any)
Description of additional data files (if any)
You can download a template (compatible with Mac and Windows Word 97/98/2000/2003/2007) for your article. For instructions on use, see below.
The Accession Numbers of any nucleic acid sequences, protein sequences or atomic coordinates cited in the manuscript should be provided, in square brackets and include the corresponding database name; for example, [EMBL:AB026295, EMBL:AC137000, DDBJ:AE000812, GenBank:U49845, PDB:1BFM, Swiss-Prot:Q96KQ7, PIR:S66116].
The databases for which we can provide direct links are: EMBL Nucleotide Sequence Database (EMBL), DNA Data Bank of Japan (DDBJ ), GenBank at the NCBI (GenBank), Protein Data Bank (PDB), Protein Information Resource (PIR) and the Swiss-Prot Protein Database (Swiss-Prot).
Title page
This should list the title of the article. The title should include the study design, for example:
A versus B in the treatment of C: a randomized controlled trial
X is a risk factor for Y: a case control study
The full names, institutional addresses, and e-mail addresses for all authors must be included on the title page. The corresponding author should also be indicated.
Abstract
The abstract of the manuscript should not exceed 350 words and must be structured into separate sections: Background, the context and purpose of the study; Methods, how the study was performed and statistical tests used; Results, the main findings; Conclusions, brief summary and potential implications. Please minimize the use of abbreviations and do not cite references in the abstract; Trial registration, if your research article reports the results of a controlled health care intervention, please list your trial registry, along with the unique identifying number, e.g. Trial registration: Current Controlled Trials ISRCTN73824458. Please note that there should be no space between the letters and numbers of your trial registration number.
Background
The background section should be written from the standpoint of researchers without specialist knowledge in that area and must clearly state - and, if helpful, illustrate - the background to the research and its aims. Reports of clinical research should, where appropriate, include a summary of a search of the literature to indicate why this study was necessary and what it aimed to contribute to the field. The section should end with a very brief statement of what is being reported in the article.
Methods
This should include the design of the study, the setting, the type of participants or materials involved, a clear description of all interventions and comparisons, and the type of analysis used, including a power calculation if appropriate.
Results and Discussion
The Results and Discussion may be combined into a single section or presented separately. Results of statistical analysis should include, where appropriate, relative and absolute risks or risk reductions, and confidence intervals. The results and discussion sections may also be broken into subsections with short, informative headings.
Conclusions
This should state clearly the main conclusions of the research and give a clear explanation of their importance and relevance. Summary illustrations may be included.
List of abbreviations
If abbreviations are used in the text, either they should be defined in the text where first used, or a list of abbreviations can be provided, which should precede the competing interests and authors' contributions.
Competing interests
A competing interest exists when your interpretation of data or presentation of information may be influenced by your personal or financial relationship with other people or organizations. Authors should disclose any financial competing interests but also any non-financial competing interests that may cause them embarrassment were they to become public after the publication of the manuscript.
Authors are required to complete a declaration of competing interests. All competing interests that are declared will be listed at the end of published articles. Where an author gives no competing interests, the listing will read 'The author(s) declare that they have no competing interests'.
When completing your declaration, please consider the following questions:
Financial competing interests
In the past five years have you received reimbursements, fees, funding, or salary from an organization that may in any way gain or lose financially from the publication of this manuscript, either now or in the future? Is such an organization financing this manuscript (including the article-processing charge)? If so, please specify.
Do you hold any stocks or shares in an organization that may in any way gain or lose financially from the publication of this manuscript, either now or in the future? If so, please specify.
Do you hold or are you currently applying for any patents relating to the content of the manuscript? Have you received reimbursements, fees, funding, or salary from an organization that holds or has applied for patents relating to the content of the manuscript? If so, please specify.
Do you have any other financial competing interests? If so, please specify.
Non-financial competing interests
Are there any non-financial competing interests (political, personal, religious, ideological, academic, intellectual, commercial or any other) to declare in relation to this manuscript? If so, please specify.
If you are unsure as to whether you or one of your co-authors has a competing interest, please discuss it with the editorial office.
Authors' contributions
In order to give appropriate credit to each author of a paper, the individual contributions of authors to the manuscript should be specified in this section.
An "author" is generally considered to be someone who has made substantive intellectual contributions to a published study. To qualify as an author one should 1) have made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data; 2) have been involved in drafting the manuscript or revising it critically for important intellectual content; and 3) have given final approval of the version to be published. Each author should have participated sufficiently in the work to take public responsibility for appropriate portions of the content. Acquisition of funding, collection of data, or general supervision of the research group, alone, does not justify authorship.
We suggest the following kind of format (please use initials to refer to each author's contribution): AB carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript. JY carried out the immunoassays. MT participated in the sequence alignment. ES participated in the design of the study and performed the statistical analysis. FG conceived of the study, and participated in its design and coordination and helped to draft the manuscript. All authors read and approved the final manuscript.
All contributors who do not meet the criteria for authorship should be listed in an acknowledgements section. Examples of those who might be acknowledged include a person who provided purely technical help, writing assistance, or a department chair who provided only general support.
Authors' information
You may choose to use this section to include any relevant information about the author(s) that may aid the reader’s interpretation of the article, and understand the standpoint of the author(s). This may include details about the authors' qualifications, current positions they hold at institutions or societies, or any other relevant background information. Please refer to authors using their initials. Note this section should not be used to describe any competing interests.
Acknowledgements and Funding
Please acknowledge anyone who contributed towards the study by making substantial contributions to conception, design, acquisition of data, or analysis and interpretation of data, or who was involved in drafting the manuscript or revising it critically for important intellectual content, but who does not meet the criteria for authorship. Please also include their source(s) of funding. Please also acknowledge anyone who contributed materials essential for the study.
The role of a medical writer must be included in the acknowledgements section, including their source(s) of funding.
Authors should obtain permission to acknowledge from all those mentioned in the Acknowledgements.
Please list the source(s) of funding for the study, for each author, and for the manuscript preparation in the acknowledgements section. Authors must describe the role of the funding body, if any, in study design; in the collection, analysis, and interpretation of data; in the writing of the manuscript; and in the decision to submit the manuscript for publication.
References
All references must be numbered consecutively, in square brackets, in the order in which they are cited in the text, followed by any in tables or legends. Reference citations should not appear in titles or headings. Each reference must have an individual reference number. Please avoid excessive referencing. If automatic numbering systems are used, the reference numbers must be finalized and the bibliography must be fully formatted before submission.
Only articles and abstracts that have been published or are in press, or are available through public e-print/preprint servers, may be cited; unpublished abstracts, unpublished data and personal communications should not be included in the reference list, but may be included in the text and referred to as "unpublished data", "unpublished observations", or "personal communications" giving the names of the involved researchers. Notes/footnotes are not allowed. Obtaining permission to quote personal communications and unpublished data from the cited author(s) is the responsibility of the author. Journal abbreviations follow Index Medicus/MEDLINE. Citations in the reference list should contain all named authors, regardless of how many there are.
Examples of the BMC Medical Genomics reference style are shown below. Please take care to follow the reference style precisely; references not in the correct style may be retyped, necessitating tedious proofreading.
Links
Web links and URLs should be included in the reference list. They should be provided in full, including both the title of the site and the URL, in the following format: The Mouse Tumor Biology Database [http://tumor.informatics.jax.org/mtbwi/index.do]
BMC Medical Genomics reference style
Style files are available for use with popular bibliographic management software:
BibTeX
EndNote style file
Reference Manager
Zotero
Article within a journal
1. Koonin EV, Altschul SF, Bork P: BRCA1 protein products: functional motifs. Nat Genet 1996, 13:266-267.
Article within a journal supplement
2. Orengo CA, Bray JE, Hubbard T, LoConte L, Sillitoe I: Analysis and assessment of ab initio three-dimensional prediction, secondary structure, and contacts prediction. Proteins 1999, 43(Suppl 3):149-170.
In press article
3. Kharitonov SA, Barnes PJ: Clinical aspects of exhaled nitric oxide. Eur Respir J, in press.
Published abstract
4. Zvaifler NJ, Burger JA, Marinova-Mutafchieva L, Taylor P, Maini RN: Mesenchymal cells, stromal derived factor-1 and rheumatoid arthritis [abstract]. Arthritis Rheum 1999, 42:s250.
Article within conference proceedings
5. Jones X: Zeolites and synthetic mechanisms. In Proceedings of the First National Conference on Porous Sieves: 27-30 June 1996; Baltimore. Edited by Smith Y. Stoneham: Butterworth-Heinemann; 1996:16-27.
Book chapter, or article within a book
6. Schnepf E: From prey via endosymbiont to plastids: comparative studies in dinoflagellates. In Origins of Plastids. Volume 2. 2nd edition. Edited by Lewin RA. New York: Chapman and Hall; 1993:53-76.
Whole issue of journal
7. Ponder B, Johnston S, Chodosh L (Eds): Innovative oncology. In Breast Cancer Res 1998, 10:1-72.
Whole conference proceedings
8. Smith Y (Ed): Proceedings of the First National Conference on Porous Sieves: 27-30 June 1996; Baltimore. Stoneham: Butterworth-Heinemann; 1996.
Complete book
9. Margulis L: Origin of Eukaryotic Cells. New Haven: Yale University Press; 1970.
Monograph or book in a series
10. Hunninghake GW, Gadek JE: The alveolar macrophage. In Cultured Human Cells and Tissues. Edited by Harris TJR. New York: Academic Press; 1995:54-56. [Stoner G (Series Editor): Methods and Perspectives in Cell Biology, vol 1.]
Book with institutional author
11. Advisory Committee on Genetic Modification: Annual Report. London; 1999.
PhD thesis
12. Kohavi R: Wrappers for performance enhancement and oblivious decision graphs. PhD thesis. Stanford University, Computer Science Department; 1995.
Link / URL
13. The Mouse Tumor Biology Database [http://tumor.informatics.jax.org/mtbwi/index.do]
Microsoft Word template
Although we can accept manuscripts prepared as Microsoft Word, RTF or PDF files, we have designed a Microsoft Word template that can be used to generate a standard style and format for your article. It can be used if you have not yet started to write your paper, or if it is already written and needs to be put into BMC Medical Genomics style.
Download the template (Mac and Windows compatible Word 1998/2000) from our site, and save it to your hard drive. Double click the template to open it.
How to use the BMC Medical Genomics template
The template consists of a standard set of headings that make up a BMC Medical Genomics Research article manuscript, along with dummy fragments of body text. Follow these steps to create your manuscript in the standard format:
Replace the dummy text for Title, Author details, Institutional affiliations, and the other sections of the manuscript with your own text (either by entering the text directly or by cutting and pasting from your own manuscript document).
If there are sections which you do not need, delete them (but check the rest of the Instructions for Authors to see which sections are compulsory).
If you need an additional copy of a heading (e.g. for additional figure legends) just copy and paste.
For the references, you may either manually enter the references using the reference style given, or use bibliographic software to insert them automatically. We provide style files for EndNote, Reference Manager and Zotero.
For extra convenience, you can use the template as one of your standard Word templates. To do this, put a copy of the template file in Word's 'Templates' folder, normally C:\Program Files\Microsoft Office\Templates on a PC. The next time you create a new document in Word using the File menu, the template will appear as one of the available choices for a new document.
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Preparing illustrations and figures
Figures should be provided as separate files. Each figure should comprise only a single file. There is no charge for the use of color.
Please read our figure preparation guidelines for detailed instructions on maximising the quality of your figures,
Formats
The following file formats can be accepted:
EPS (preferred format for diagrams)
PDF (also especially suitable for diagrams)
PNG (preferred format for photos or images)
Microsoft Word (figures must be a single page)
PowerPoint (figures must be a single page)
TIFF
JPEG
BMP
CDX (ChemDraw)
TGF (ISIS/Draw)
Figure legends
The legends should be included in the main manuscript text file rather than being a part of the figure file. For each figure, the following information should be provided: Figure number (in sequence, using Arabic numerals - i.e. Figure 1, 2, 3 etc); short title of figure (maximum 15 words); detailed legend, up to 300 words.
Please note that it is the responsibility of the author(s) to obtain permission from the copyright holder to reproduce figures or tables that have previously been published elsewhere.
Editorial Board
BMC Medical Genomics Section Editors
Debashis Ghosh
Penn State University, USA
Struan Grant
Childrens Hospital of Philadelphia Research Institute, USA
Patrice Morin
National Institute on Aging, USA
Patrick Tan
Genome Institute of Singapore, Duke-NUS Graduate Medical School, Singapore
BMC Medical Genomics Editorial Board Members
Timothy Aitman
Imperial College London, UK
Russ Altman
University of Stanford, USA
Stephan Beck
University College London, UK
Philip Bernard
University of Utah, USA
Kenneth Blum
University of Florida School of Medicine, USA
Atul Butte
University of Stanford, USA
Wei Dai
NYU Medical Center, USA
Panos Deloukas
Sanger Centre, UK
Johan T den Dunnen
Leiden University Medical Centre, Netherlands
Emmanuel Dias-Neto
University of Texas, MD Anderson Cancer Center, USA & University of São Paulo, Brazil
William Feero
National Human Genome Research Institute, USA
Philippe Froguel
Imperial College London, UK
Teri Klein
Stanford University, USA
Isaac Kohane
Harvard Medical School, USA
Yusuke Nakamura
University of Tokyo, Japan
Dan Nicolae
University of Chicago, USA
Markus Perola
National Public Health Institute, Finland
Brien P Riley
Virginia Commonwealth University, USA
H.-Hilger Ropers
Max Planck Institute for Molecular Genetics, Germany
Chris Sander
Memorial Sloan-Kettering Cancer Center, USA
Stephen W Scherer
The Hospital for Sick Children, Canada
Wim van Hul
University of Antwerp, Belgium
Philippe Van Trappen
Academic Hospital Maastricht, Netherlands
BMC Medical Genomics Associate Editors
Jonas Almeida
University of Texas MD Anderson Cancer Center, USA
Kevin Becker
National Institute on Aging, USA
Paul Boutros
Ontario Institute for Cancer Research, Canada
Philippe Broet
INSERM, France
Kevin Brown
Translational Genomics Research Institute, USA
Jen-Tsan Ashley Chi
Duke Medical Center, USA
William CS Cho
Queen Elizabeth Hospital, Hong Kong
Frank H Collins
University of Notre Dame, USA
Francesca Demichelis
Weill Cornell Medical College, USA
Jörg Epplen
Ruhr University, Germany
Paul Franks
Umea University Hospital, Sweden
James Fuscoe
U.S. Food and Drug Administration - National Center for Toxicological Research, USA
Debashis Ghosh
Penn State University, USA
Struan Grant
Childrens Hospital of Philadelphia Research Institute, USA
Jeffrey P Gregg
University of California, Davis, USA
Lyndsay Harris
Yale University Medical Center, USA
Anke Hinney
University of Duisburg-Essen, Germany
Jaakko Hollmén
Aalto University School of Science and Technology, Finland
Qihong Huang
The Wistar Institute, Philadelphia, USA
James Jarvis
University of Oklahoma College of Medicine, USA
Yinglei Lai
The George Washington University, USA
William Lockwood
Memorial-Sloan Kettering Cancer Center, USA
Sharon Marsh
Quebec and Montreal Heart Institute Pharmacogenomics Centre, Canada
Mark McCarthy
Oxford Centre for Diabetes, Endocrinology and Metabolism, UK
Patrice Morin
National Institute on Aging, USA
Sayan Mukherjee
Duke University, USA
Maggie CY Ng
Wake Forest University School of Medicine, USA
Philippos Patsalis
The Cyprus Institute of Neurology and Genetics, Cyprus
Miguel Angel Pujana
Bellvitge Institute for Biomedical Research (IDIBELL), Spain
Frank R Sharp
University of California, Davis, USA
Kerby Shedden
The University of Michigan, USA
Patrick M.A. Sleiman
Childrens Hospital of Philadelphia, USA
Patrick Tan
Genome Institute of Singapore, Duke-NUS Graduate Medical School, Singapore
George C Tseng
University of Pittsburgh, USA
Ashani Weeraratna
National Institute on Aging, USA
Mingqing Xu
Harvard University, USA
Pearlly Yan
Ohio State University, USA
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