期刊名称:CYTOGENETIC AND GENOME RESEARCH
期刊简介(About the journal)
投稿须知(Instructions to Authors)
编辑部信息(Editorial Board)
About the journal
This journal is a leading forum for original research in mammalian cytogenetics and molecular genetics including
gene cloning and sequencing, gene mapping, cancer genetics, comparative genetics, gene linkage, and related areas. In addition, the journal publishes key papers on chromosome aberrations in somatic, meiotic and malignant cells of man and other animals. Also featured are the vast majority of the reports of the individual International Workshops on Human Chromosome Mapping.
Instructions to Authors
Categories of Reports and Sections
 Full reports, brief reports, and commentaries are published if found to be acceptable by at least two peer reviewers.
 Full reports are published within the main general section, or where appropriate, within some of the special sections described below.
 High priority reports: Papers containing information deemed to be of particular benefit to the scientific community will be published as soon as possible after acceptance. Authors who believe their papers qualify for such accelerated processing should request this when they submit the paper for publication. The Editors reserve the right to determine if a particular report qualifies for such accelerated processing.
 Cytotaxonomy and comparative mapping:This section includes full or short reports of cytotaxonomic and comparative molecular genetic studies as well as reports of the chromosome complements of rare or endangered species.
 Brief gene mapping reports: This section is intended to provide a rapid means of reporting findings in these areas. Such reports should be prepared according to the guidelines and the standardized format described in the Editorial in Vol. 94:106?10 (2001) and under Guidelines for preparing brief gene mapping reports. Brief gene mapping reports are not published in their entirety. Instead, only the title, authors and their affiliations are printed in the Journal and the report is made accessible for free on the Journal site. Forms of the standardized format can be accessed below (Guidelines for Gene Mapping Reports). Electronic versions of these forms can also be obtained via e-mail from hklinger@aecom.yu.edu.
 Full gene mapping, cloning, sequencing and gene characterization reports: Full descriptions of newly mapped genes are accepted for publication if they meet all the criteria outlined for the brief gene mapping reports (see below) and, in addition, present a reasonably full characterization of the gene. These reports should not be expansions of brief reports but should constitute reasonably comprehensive, but not necessarily all inclusive, characterization of the mapped gene including, for example, information on its function, its gene expression characteristics, sequence, etc. Although no form is provided for these full mapping reports authors are advised to consult the brief report instructions and forms to be sure that they include all the information shown on these forms to which they can add the additional information they consider appropriate. These reports should also be prepared in a concise manner with an abstract of about 60 words. All contributions for this section will be peer reviewed like all papers received by this Journal.
 Collaborative and interactive research projects: This section is for investigators who are in need of specific research materials, or need the assistance of colleagues with specialized expertise and for investigators who have data that is inadequate for a full report but which could be published when combined with data of other investigators. To give but some examples, this section may include requests for collaborators on specific research projects or requests for specific research materials such as molecular probes, sera, antibodies or other special reagents. Other examples are requests for subjects with certain types of diseases or specific mutant microorganisms, plants, animals, or rare animal species or tissue samples from such rare species. The paper by M. Schmid, Vol. 94:111?12 (2001) is an example of such a proposal for an interactive project. For further details see the Editorial in Vol. 94:106?10 (2001).
 Commentaries: Contributions to this section, intended as a forum for observations, opinions, and comments outside the realm of conventional scientific papers, must be completely original and unpublished. Original data, tables, and illustrations may be included, provided these meet the established criteria. Preliminary reports or information to be published elsewhere will not be accepted. No abstract is required.

Submission
 Manuscripts from authors in the Western Hemisphere, from Japan and China, and all gene mapping reports should be sent to:
 Harold P. Klinger Department of Molecular Genetics Albert Einstein College of Medicine 1300 Morris Park Avenue Bronx, NY 10461¨C1602, USA Tel.: (718) 430¨C2451; Fax: (718) 430-2454 E-mail: hklinger@aecom.yu.edu
 Manuscripts from authors in the Eastern Hemisphere and all animal cytogenetic papers, including comparative genetic and cytogenetic ones, should be sent to:
 Michael Schmid Department of Human Genetics University of W¨¹rzburg Biozentrum, Am Hubland D¨C97074 W¨¹rzburg, Germany Tel.: (49) 931 888¨C4077; Fax: (49) 931 888¨C4069 E-mail: m.schmid@biozentrum.uni-wuerzburg.de

Important Note
 In order to accelerate the manuscript review process, we request that if at all possible authors submit their manuscripts as attachments via email only. Hard copies are not required if the text and graphics are in one of the more commonly used formats. No processing fee is then required for such submissions. Since only relatively few word processing programs are in common use, and excellent conversion programs are available, transfer of text generally does not present a problem.
 Graphics can be more problematic since there are a large number of graphic formats in use, and not all can be converted successfully to more common formats, or converted so that the full resolution of the original is maintained. Therefore, we request that all graphics be in one of the more common formats such as those of Microsoft Photo Editor, Power Point, Adobe Photoshop or Acrobat, Dell Picture Studio, Paintbrush, and Picture Gear, to give some examples. Thus, files with the extensions .jpg (.jpeg .jpe), .gif, .bmp (.rle), .tif (.tiff) .eps, .ppt, .psd (.pdd), .pxr, .png and .pcx are examples of the most desired formats. Although, as indicated, Adobe Acrobat (.pdf) graphic files are acceptable we do not want .pdf text files. Resolution of the graphics should be at least 300 dots per inch, but higher resolution is recommended, particularly if there is fine detail in the illustration. Authors who are not certain if the format they use is acceptable should check with the Editorial Office in New York (hklinger@aecom.yu.edu). Because the size of email messages is limited in many email systems it may be necessary to send large graphics files separately. In all cases, please be certain that the first author’s initials precede the file name of all figures and tables in attachments to avoid confusion with those of other papers that may arrive on the same day.
 We expect to change to a better system in the near future whereby manuscripts will be submitted via the Internet. This system will be announced when it becomes available.
 All electronic submissions will be confirmed via email within three working days and the authors will be given a manuscript number. They should refer to this number in any communications related to their report. Reviewer’s recommendations and the decision as to the publication of the report will be sent via email to the corresponding author. It is therefore essential that this author’s email address appears on the title page of the report. Telephone and fax numbers as well as a full mailing address should also appear on the title page.
 Authors should indicate in their letter of submission which of the Executive or Associate Editors they feel would be most appropriate for their report. If possible two or more of these Editors should be listed to allow equitable distribution of the workload. If this is not indicated then the Chief Editors will select the Executive or Associate Editors who will process the manuscript, or they will send the manuscript directly to the reviewers. Authors will be informed in the acknowledgment of the manuscript receipt which of these alternatives has been elected. Where appropriate, they will be told which Executive or Associate Editor is processing the report. They should then address all future correspondence to that Editor. The postal and e-mail addresses as well as telephone and fax numbers for all of these Editors are printed on the title page of each issue of this journal.

Manuscript Processing Fee
 Authors who do not submit their manuscripts electronically will be required to include a manuscript processing fee of USD 85.00 for full reports and USD 50.00 for brief gene mapping reports, or for other short reports, that will not encompass more than three printed pages. (Approximately nine double spaced pages in 12 point type including illustrations, legends and references.) These fees are required for the labor involved in scanning hard copies or, when the scanned illustrations are not of adequate quality, for the costs of courier services for sending the manuscript to reviewers and to the printers.
 A check or bank transfer made out to S. KARGER AG,, not to the journal or its editors, or the appropriate credit card information should then accompany the manuscript. The fee will not be refunded if the manuscript is not accepted for publication since this still incurs processing costs.

Arrangement
 Manuscripts must be prepared strictly in accordance with the style of this journal. Contributions which are accepted will normally be printed in order of receipt except when revisions are necessary or other delays that are beyond editorial control occur.
 Title page: The first page should give the full names of the authors and their affiliations, an abbreviated running title, full postal address, telephone and fax numbers, as well as e-mail address.
 Abstract: A short abstract should be provided for all full reports.
 Tables and illustrations: To reproduce well all digital illustrations should be sharp with good contrast and color rendition in the case of color illustrations. Resolution for all graphics should be at least 300 dots per inch.

Literature Cited
 References should be quoted in the text as follows:
| Single author: |
Jones (1999) |
| Two authors: |
Jones and Smith (2000) |
| More than two authors: |
Jones et al. (2001) | The reference list should be arranged alphabetically according to the first author’s surname.
 Titles should be given in full.
 Papers published in electronic format should list authors, title and journal as above followed by the journal's URL, eg:
Black CA: Delayed type hypersensitivity: Current theories with a historic perspective. Dermatol Online J 5:7 (1999). http://dermatology.cdlib.org/DOJvol5num1. |
Book references must include the book title, editor(s), publisher, and city of publication.
 Recent issues of the Journal should be carefully consulted for reference list style.
 Agreement between text citations and the reference list should be checked carefully, and the latter checked for accuracy. If many errors are found, the manuscript will be returned for corrections which may cause considerable publication delay.

Gene Symbols
 Human gene symbols: Only official gene symbols of the International System for Gene Nomenclature (ISGN) are accepted. Authors must obtain or verify the official gene symbol of the gene(s) mapped and indicate that they have done so in the manuscript submitted. This can be accomplished for human genes by contacting
 Dr. Sue Povey HUGO Gene Nomenclature Committee Department of Biology University College London Wolfson House 4 Stephenson Way London NW1 2HE (UK) Tel.: +44 20 7679 7410 Fax: +44 20 7387 3496 E-Mail nome@galton.ucl.ac.uk website: www.gene.ucl.ac.uk/nomenclature/
 Animal gene symbols: Authors submitting material on mouse and rat genetics should obtain correct genetic nomenclature before publication. Contact
 Dr. Lois Maltais MGD Nomenclature Coordinator The Jackson Laboratory 600 Main Street Bar Harbour ME 04609 (USA) Tel. +1 (207) 288 6429 Fax +1 (207) 288 6132 E-mail nomen@informatics.jax.org MGD home page: www.informatics.jax.org
 Guidelines set forth by the International Committee on Standardized Genetic Nomenclature for Mice are available at www.informatics.jax.org/mgihome/nomen/table.shtml
 New symbols and names for genes can be requested electronically through the online symbol registry form at www.informatics.jax.org/mgihome/nomen
 Gene mapping data for the mouse should also be submitted to the Mouse Genome Database (MGD) following the guidelines at www.informatics.jax.org/mgihome/submissions/submit.shtml.
 The assigned MDG accession numbers should be included in the manuscript for publication. Assistance with submission can be obtained at www.informatics.jax.org/mgihome/submissions/submissions_menu.shtml or by by sending an e-mail to submissions@informatics.jax.org

Charges for Extra Pages or Illustrations and for all Color Reproductions
 This journal will defray the costs of the first five printed pages (a total of about 5,000 words minus any tables or figures). Any additional pages will have to be defrayed on a cost-sharing basis by the authors at the rate of USD 200.00 per page.
 Authors must defray the extra costs of figure reproductions exceeding two printed pages as well as the full cost of all color reproductions at USD 320.00 per page (up to six color reproductions per page).
 Authors with limited funds may apply for dispensation from these costs (except color plates) by submitting an appropriately documented letter after they have been notified that their manuscript has been accepted for publication and they have been provided with an estimate of the manuscript's printed length.

Galley Proofs
 Electronic galley proofs will be emailed to the first-named author unless another is indicated.

Reprints
 They are available against payment. Order forms listing prices will be sent with the galley proofs. Orders submitted after the issue is printed are subject to considerably higher prices.

Guidelines for Reports on Plant and Invertebrate Studies
 The Editors of this Journal believe that in this molecular era of biology, cytogeneticists in all areas of the field could learn a great deal from each other. Consequently, in conjunction with the establishment of the International Cytogenetics and Genome Society that is open to cytogeneticists of all interests in the field, reports on plants and invertebrates will now be considered for publication.
 However, it must be stressed that similar to our long-standing policy for mammalian, including human cytogenetic reports, papers describing the karyotype of one or a few species or of previously published chromosome abnormalities, will not be accepted. As an exception to this policy, chromosome descriptions of very rare species, or of species threatened to become extinct, will be considered for publication if the chromosomes of these species has not been published previously. In some cases the Editors may elect to handle such reports the same way as brief mapping reports are handled. In such cases the author's approval will be sought first. Some examples of the types of papers that will be considered for publication are reports on gene expression or function in plants and animals; reports revealing basic genetic or other biologic phenomena; and reports on chromosome structure and function. In addition, comparative cytogenetic as well as comparative gene mapping reports; cytotaxonomic reports demonstrating relationships between taxonomic groups; or those demonstrating evolutionary relationships or trends will also be acceptable.
 Brief and full gene localizations (mapping) reports in all plants and all animals will be considered for publication following the same procedures used for human gene mapping reports. Brief gene mapping reports are not published in their entirety. Instead, only the title, authors, and their affiliations are printed in the Journal and the text and any figures will be available on the Journal Internet site for free. Brief gene mapping reports should be prepared according to the guidelines and the standardized format described in the Vol. 94:106?10 (2001), or here below.
 Full mapping, cloning, sequencing and gene characterization reports must be of newly mapped genes and must meet the criteria outlined above for the brief gene mapping reports. In addition, they must present a reasonably full characterization of the gene and should not be expansions of brief reports but should constitute reasonably comprehensive, but not necessarily all inclusive, characterization of the mapped gene, including, for example, information on its function, its expression characteristics, its DNA sequence, etc. Although no form is provided for these full reports authors are advised to consult the brief report instructions below and be sure that they include all the information shown on the brief mapping report forms. Authors can then add the additional information they consider appropriate. These reports should also be prepared in as concise a manner as possible with an abstract of about 60 words.
 All mapping reports will be peer reviewed like all papers received by this Journal. Authors of all types of reports are encouraged to provide names of colleagues they consider as appropriate peer reviewers of their contributions. However, the editors may not necessarily send papers to those the author lists.


Guidelines for Preparing Brief Gene Mapping Reports Cytogen Cell Genet 94:108 (2001)
 These guidelines also apply to full gene mapping reports except that the latter should not be on the brief mapping report forms
Guidelines
 The title, authors and affiliations only of brief gene mapping reports are published in Cytogenetic and Genome Research. The report itself is put on the Journal's Internet site and will be freely accessible.
 In order to be able to disseminate the information on the increasing number of genes being mapped quickly and efficiently, and to provide a uniform format that will facilitate the retrieval of mapping data and assure the inclusion of all the essential information, we request that all brief gene mapping reports be prepared according to the format shown below. One of these forms is for genes mapped with in situ hybridization methods, the other when somatic cell hybrids are used. If both methods are used then the appropriate sections from each of these forms can be combined. When the in situ method is used a photograph should be included to allow the reader to verify the location of the signals. When somatic cell hybrids are used the authors should send photographs showing parental rodent, human, as well as cell hybrid phenotypes for verification by reviewers. Mapping reports will be peer reviewed just like all papers processed by this Journal.
 Authors should provide all the information indicated on the form that is relevant to their report. All other items on the forms can be left off.
 The name of the author who is prepared to answer inquiries about the report, his/her address, telephone and fax numbers, as well as e-mail address should be included. These should be entered where indicated at the bottom of the form. If this author is different from the one to receive proof and/or the reprints then the appropriate information should also be given in the letter of submission.
 Authors must obtain or verify the official gene symbol of the gene(s) mapped. This can be accomplished for human genes by contacting Dr. Sue Povey HUGO Gene Nomenclature Committee Department of Biology University College London Wolfson House 4 Stephenson Way London NW1 2HE (UK) Tel.: +44 20 7679 7410 Fax: +44 20 7387 3496 E-Mail nome@galton.ucl.ac.uk website: www.gene.ucl.ac.uk/nomenclature/
 Mouse and rat gene symbols can be obtained from
 Dr. Lois Maltais MGD Nomenclature Coordinator The Jackson Laboratory 600 Main Street Bar Harbour ME 04609 (USA) Tel. +1 (207) 288 6429 Fax +1 (207) 288 6132 E-mail nomen@informatics.jax.org MGD home page: www.informatics.jax.org
 Authors must indicate in their covering letter that they have confirmed that the gene symbol(s) used is the official symbol. Authors need not follow the double column format shown below but should maintain the same sequence of the items. All inappropriate items and instructions on the forms, including the Journal and form names at the top should be deleted.  Authors whose text processing programs do not allow the formatting shown should use whatever format is convenient but should maintain the same sequence of the items. Authors must then be careful that the amount of text will allow it all to fit on one page. All inappropriate items and instructions on the forms, including the Journal and form names at the top should be deleted.
 Electronic version of the forms can be obtained via e-mail from the Editorial Office in New York at the e-mail address: hklinger@aecom.yu.edu
 The electronic version as well as two hard copies of all mapping reports should be sent to the Editorial Office in New York. (Please note that this is in contrast to other types of reports where authors in the eastern hemisphere of the world are requested to send their papers to Dr. Michael Schmid in Germany.) A processing fee of USD 50.00 should accompany the report. If more than one report is sent at the same time an additional USD 30.00 should be added for each report. (For specifics please see Manuscript Processing Fee in the general Guidelines for Authors above).

Requirements that gene mapping reports must meet to be considered for publication
 1. The gene must be previously unmapped by any technique. This means that papers of mapping confirmations will no longer be accepted. Relocations of genes incorrectly mapped within a major chromosome band, i.e. to a different subband, will not be accepted. However, genes that are relocated a significant distance from the one to which it had been assigned, or to another chromosome, will be accepted. The evidence for the new assignment must be obtained with two different methods.
 2. Well-described flanking markers must be given for all mapping assignments. The relative location of the flanking markers can be established by standard radiation hybrid or mouse backcross panels. For mapping by fluorescence in situ hybridization (FISH), the markers must be within 5 cM or 5 Mb of the gene or genes that have been mapped.
 3. The results from DNA sequence database searches must be given for the mapped gene(s). The entire sequences should not be given, just the size, degree of the matches and their significance. If several sequences are involved, this should be presented in a concise table listing the standardized gene names as established by the HUGO Gene Nomenclature Committee (see above) and accession numbers of the matching sequences. The human chromosome reference sequences nucleotide position of mapped genes should also be given as they become available.
 4. The following categories must be collected into a single publication if submitted from one group of investigators: (a) All cDNAs representing a single multigene family. (b) Genes located within a single chromosome band. (c) A series of orthologous genes when results of comparative mapping studies of mouse (or some other species) and human genes are reported.
 5. Authors of both accepted and not accepted papers are encouraged to submit their data to mapping databases. The Genome Database (www.gdb.org) is prepared to accept the data if presented in the short report format.
Forms for reports of gene mapping
 in PDF format*:
 by in situ hybridization (85 KB)
 with somatic cell hybrids (87 KB)
 *To read and print out these forms Acrobat Reader by Adobe is required.
 as word documents: by in situ hybridization
 with somatic cell hybrids
Instructions to Authors
Somatic-1424-8581.doc insitu-1424-8581.doc Somatic-1424-8581.pdf insitu-1424-8581.pdf
Editorial Board
Chief Editors
 Harold P. Klinger Department of Molecular Genetics Albert Einstein College of Medicine 1300 Morris Park Avenue Bronx, NY 10461¨C1602, USA Tel.: (718) 430¨C2451; Fax: (718) 430-2454 E-mail: hklinger@aecom.yu.edu
 Michael Schmid Department of Human Genetics University of W¨¹rzburg Biozentrum, Am Hubland D¨C97074 W¨¹rzburg, Germany Tel.: (49) 931 888¨C4077; Fax: (49) 931 888¨C4058 E-mail: m.schmid@biozentrum.uni-wuerzburg.de

 Managing Editors
 Judith A. Hartz Department of Molecular Genetics Albert Einstein College of Medicine 23055 Wahupa, Huson, MT 59846, USA E-mail: hartz@aecom.yu.edu
 Martina Guttenbach Department of Human Genetics University of W¨¹rzburg Biozentrum, Am Hubland D¨C97074 W¨¹rzburg, Germany E-mail: guttenbach@biozentrum.uni-wuerzburg.de

 Co-Editor-in-Chief
 Molecular cytogenetics and molecular pathology Linda A. Cannizzaro Department of Pathology Montefiore Medical Center 111E 210th Street Bronx, NY 10467, USA Tel.: (718) 920?929; Fax: (718) 515?879 E-mail: cannizza@aecom.yu.edu

 Editorial Administrator
 Barbara Grandinetti (Callaci), Bronx, NY Department of Molecular Genetics Albert Einstein College of Medicine 1300 Morris Park Avenue Bronx, NY 10461¨C1602, USA

 Assistant Editors
 Edwin S. Geffner, Huntington, NY Pauline H. Geffner, Huntington, NY

 Executive Editors
 Gene mapping, cloning, molecular genetics Thomas B. Shows Department of Cancer Genetics Roswell Park Cancer Institute Elm and Carlton Streets Buffalo, NY 14263, USA Tel.: (716) 845¨C3108; Fax: (716) 845¨C8449 E-mail: tbs@shows.med.buffalo.edu
 Molecular cytogenetics, gene mapping, somatic cell genetics, informatics Peter L. Pearson Division of Medical Genetics KC.04.084.2 Wilhelmina Children¡¯s Hospital University Medical Center P.O. Box 85090 NL¨C3508 AB Utrecht, The Netherlands Tel.: (31) 30 250-3820/3815; Fax: (31) 30 250-5301 E-mail: p.l.pearson@med.uu.nl

 Associate Editors and Sections
 Comparative cytogenetics Thomas Haaf Max-Planck-Institute of Molecular Genetics Ihnestrasse 73 D¨C14195 Berlin, Germany Tel.: (49) 30 8413 1251; Fax: (49) 30 8413 1383 E-mail: haaf@molgen.mpg.de
 Horst Hameister Abteilung Medizinische Genetik Universitätsklinikum Ulm Albert-Einstein-Allee 11 D¨C89070 Ulm, Germany Tel.: (49) 731-502 34 36; Fax: (49) 31-502 34 38 E-mail: horst.hameister@medizin.uni-ulm.de
 Molecular cytogenetics and gene mapping Anne Kallioniemi Laboratory of Cancer Genetics Institute of Medical Technology University of Tampere P.O. Box 607 FIN-33014 Tampere (Finland) Tel.: +35 8-3-247-4125; Fax: +35 8-3-247-4168 E-mail: Anne.Kallioniemi@uta.fi
 Molecular cytogenetics, gene mapping and molecular and developmental genetics Julie R. Korenberg Medical Genetics Birth Defects Center Cedars-Sinai Medical Center 110 George Burns Road Davis Bldg., Suite 2069 Los Angeles, CA 90048, USA Tel.: (310) 423?627; Fax: (310) 423?302 E-mail: julie.korenberg@cshs.org
 Molecular cytogenetics and molecular genetics of cell malignancy Peter Lichter Division ¡®Organization of Complex Genomes¡¯ Deutsches Krebsforschungszentrum Im Neuenheimer Feld 280 D¨C69120 Heidelberg, Germany Tel.: (49) 6221¨C424609; Fax: (49) 6221¨C424639 E-mail: p.lichter@dkfz-heidelberg.de
 Tumor cell genetics and somatic cell genetics Ad Geurts Van Kessel Department of Human Genetics University Hospital P.O. Box 9101 NL?500 HB Nijmegen, The Netherlands Tel.: (31) 24 361 4107; Fax: (31) 24 354 0488 E-mail: a.geurtsvankessel@antrg.azn.nl
 Medical cytogenetics Albert Schinzel Department of Medical Genetics University of Z¨¹rich R??mistrasse 74 CH-8001 Z¨¹rich, Switzerland Tel.: (41) 1 634 2521; Fax: (41) 1 634 4916 E-mail: schinzel@medgen.unizh.ch
 Plant cytogenetics and genome studies Stephen M. Stack Department of Biology Colorado State University Fort Collins, CO 80523-1878, USA Tel.: (970) 491-6802; Fax: (970) 491-0649 E-mail: stephen.stack@colostate.edu
 Genes and diseases Bernhard H.F. Weber Department of Human Genetics University of W¨¹rzburg Biozentrum, Am Hubland D?7074 W¨¹rzburg, Germany Tel.: (49) 931 888 4062; Fax: (49) 931 888 4069 E-mail: bweb@biozentrum.uni-wuerzburg.de

 Editorial Board Members
 P. Mohan R. Achary, Bronx, NY Rando Allikmets, New York, NY Terry Ashley, New Haven, CT Antonio Baldini, Houston, TX Bhanu P. Chowdhary, Frederiksberg Frederick Elder, Dallas, TX Henry Heng, Detroit, MI Suresh Jhanwar, New York, NY Neil Jones, Aberystwyth, Wales, UK Nicholas Popescu, Bethesda, MD Harry Scherthan, Kaiserslautern Ingo Schubert, Gantersleben Stuart Schwartz, Cleveland, OH Jeremy B. Searle, York Jacqueline Smith, Roslin David M. Stelly, College Station, TX Nobuo Takagi, Sapporo Joseph R. Testa, Philadelphia, PA
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