期刊名称：METHODS
 期刊简介(About the journal)
投稿须知(Instructions to Authors)
编辑部信息(Editorial Board)
About the journal
Methods
|
Methods focuses on rapidly developing techniques in the experimental biological and medical sciences. Each topical issue, organized by an editor who is an expert in the area covered, consists of invited articles. Issues are devoted to specific technical approaches with emphasis on clear detailed descriptions of protocols that allow them to be reproduced easily. The background information provided enables researchers to understand the principles underlying the methods; other helpful sections include comparisons of alternative methods giving the advantages and disadvantages of particular methods, guidance on avoiding potential pitfalls, and suggestions for troubleshooting.
Some of the recent hot topics covered include: |
|
Preparation and Use of Brain Slices
Analysis of RNA Structure and Function Using Site-
Specific Substitution or Derivation
Apoptosis: Isolation and Characterization of Proteins
Signaling Pathways and Gene Regulation in Hematopoietic Cell Growth and Differentiation
Structure-Function Relationships in Chromatin
Regulation of mRNA Stability
Differential Display Method and Application
Techniques for the Purification, Functional Evaluation, and Transplantation of Brain Cells
Molecular Mechanisms of Exocytosis
Analysis of Viral Gene Expression in Differentiated Tissue
Instructions to Authors
The articles in the topic-oriented issues of this journal present new methods applicable to a number of disciplines. Issues are devoted to specific approaches or techniques and describe their theoretical bases. Emphasis is placed on clear descriptions of protocols that allow applications of these methods in any modern laboratory. Issues are organized by expert guest editors and consist of invited articles. Unsolicited manuscripts will not be accepted.
Manuscripts are accepted with the understanding that the same work has not been published, that it is not under consideration for publication elsewhere, and that its submission for publication has been approved by all of the authors and by the institution where the work was carried out; further, that any person cited as a source of personal communications has approved such citation. Written authorization may be required at the Editor's discretion. Articles and any other material published in Methods represent the opinions of the author(s) and should not be construed to reflect the opinions of the Editor(s) and the Publisher.
Authors submitting a manuscript do so on the understanding that if the manuscript is accepted for publication, copyright in the article, including the right to reproduce the article in all forms and media, shall be assigned exclusively to the Publisher. The Copyright Transfer Agreement should be signed by the appropriate person.
Permission to reproduce copyrighted material. Authors who plan to use illustrations, charts, tables, or other material from previously published sources must obtain written permission from the copyright owner (usually the publisher). Authors should write to the author of the original material to obtain permission as a courtesy.
If an author uses material from his/her own published work, permission must still be obtained from the publisher.
The source of the data must always be credited, e.g., in a footnote to a table, in a figure legend.
Electronic Transmission of Accepted Manuscripts. Authors are requested to transmit the text and art of the manuscript in electronic form, via computer disk, e-mail, or FTP (ftp.elsevier.com, with username anon and password essd4acc), after all revisions have been incorporated and the manuscript has been accepted for publication. Submission as an e-mail attachment is acceptable provided that all files are included in a single archive the size of which does not exceed 2 megabytes meth@elsevier.com. Hard-copy printouts of the manuscript and art must also be supplied. The manuscript will be edited according to the style of the journal, and authors must read the proofs carefully.
Preparation of Manuscript. Manuscripts should be concise and consistent in style, spelling, and use of abbreviations. To facilitate the processing of manuscripts, the journal requests that at least three copies be submitted to the editor, each copy to include all figures (originals or glossy prints) and tables. The original copy must be typewritten, double-spaced, on one side of good-quality paper, about 8 1/2 x 11 inches in size, with one-inch margins on all sides. Pages should be numbered consecutively and should include Title page, Abstract, Introduction, Description of Method, Concluding Remarks, and References.
The Title Page (p. 1) should contain the article title, authors' names and complete affiliations, footnotes to the title, and the address for manuscript correspondence (including e-mail address and telephone and fax numbers).
In creating a title for an article, please omit words such as the, a, an, novel, improved, simple, efficient, convenient, new. Each is felt to be redundant and actually slows down the reader who is scanning the article titles and wants to know more about the method itself. Please substitute informative words that will give readers a more complete idea of the usefulness of your paper with regard to the limitations of their equipment or sample type. Abbreviations should not be used in the article title or running title.
The Abstract (p. 2) must be a single paragraph that summarizes the main findings of the paper in less than 250 words. After the abstract a list of up to 10 keywords that will be useful for indexing or searching should be included. The abstract should be intelligible to nonspecialists and hence should avoid specialized terms and abbreviations or symbols that require definition.
Names of chemical or organic substances should follow the recommendations of the IUPAC-IUBMB Joint Combined Commission on Biochemical Nomenclature (JCBN).
Authors should draw attention to any particular hazards that may be involved in carrying out the methods described. Any relevant safety precautions should be described; if an accepted code of practice has been followed, a reference to the relevant standards should be given. Because the value of a method is entirely dependent on the availability of all materials, sources for critical reagents and instruments must be clearly identified.
In reports of experiments involving recombinant DNA molecules, constructed in vitro and subsequently inserted into cells, reference must be made to the appropriate NIH guidelines and/or other pertinent regulations or, if comparable documents exist in the country where the work was done, these may be referenced. Significant deviations from the recommended practices should be described. In those circumstances where the host system has been certified as disabled by the NIH Program Advisory Committee on Recombinant DNA, that certification should be noted.
References should be cited in the text by Arabic numerals in square brackets and listed at the end of the paper in consecutive order. Only articles that have been published or are in press should be included in the references. Abbreviations of journal titles should follow the style used in the most recent Chemical Abstracts Service Source Index. Unpublished results or personal communications should be cited as such in the text. Please use the following style, noting capitalization and punctuation:
[1] U. Lehmann, H. Kreipe, Methods 25 (2001) 409-418.
[2] E.C. Conley, The Ion Channel FactsBooks, Academic Press, San Diego, 2001.
[3] T. Kealey, in: Packer, L. (Ed.), Methods in Enzymology, vol. 190, Academic Press, New York, 1990, pp. 338-345.
Figures should be in a finished form suitable for publication. Number figures consecutively with Arabic numerals, and indicate the top and the authors' names on the back of each figure. Each figure should have a descriptive legend. Legends should be typed together on a separate sheet, double-spaced. Lettering on drawings should be professional quality or generated by high-resolution computer graphics and must be large enough to withstand appropriate reduction for publication. Please visit our Web site at http://authors.elsevier.com/artwork for detailed instructions on preparing electronic artwork.
Color Figures. One color plate will be published free of charge in each article. Additional color figures will be charged to the author. Color reproduction of figures in the electronic version of the article only (on ScienceDirect), with black-and-white reproduction in print, is available at no cost. However, authors must provide usable electronic files for the color versions of their figures and separate files or hard copies of the black-and-white versions of the figures. Only .tif and .eps files in RGB color mode of at least 300 dpi resolution will be accepted. If the electronic version of the art is unusable, Elsevier will not post the color version on ScienceDirect. Authors should clearly state in a cover letter sent to the editorial office at submission or at final acceptance which figures they would like reproduced in color for free in the electronic version of the article only and which figures they would like reproduced in color in the print and electronic versions at a cost to them.
Tables should be numbered consecutively with Arabic numerals in order of appearance in the text. Type each table double-spaced on a separate page with a short descriptive title typed directly above and with essential footnotes below. Authors should submit complex tables as camera-ready copy. Footnotes to tables should be placed at the bottom of the table and linked to the body of the table with the corresponding lowercase superscript letters.
Equations, if included, should be numbered, using Arabic numbers enclosed in parentheses, in sequence throughout the article. In the text, they should be referred to as Eq. (1), Eqs. (3)?(5).
Footnotes should be designated in text by superscript numbers and typed on a separate sheet following the References.
Proofs will be sent to the corresponding author. To avoid delay in publication, only necessary changes should be made, and proofs should be returned promptly. Authors will be charged for alterations that exceed 10% of the total cost of composition.
Editorial Board
-
- Editors:
K.W. Adolph, University of Minnesota, Minnesota, USA
P.M. Conn, Oregon National Primate Research Center and Oregon Health and Science University, Oregon, USA
M.P. Deutscher, University of Miami School of Medicine, Florida, USA
J.J. Langone, Food and Drug Administration, Maryland, USA
- Editorial Board:
M.Z. Atassi
F.R. Blattner
M.D.P. Boyle
K. Calame
J.-P. Changeux
J.E. Dahlberg
R.W. Davis
D.T. Denhardt
J.E. Dixon
R.F. Doolittle
E. Engvall
L. Gold
M. Gottesman
M.I. Greene
D.R. Helinski
T. Hökfelt
T. Honjo
A.J.-W. Hsueh
L.H. Kedes
K.K. Kidd
H.K. Kohler
C. Kordon
M.D. Lane
L.A. Lasky
W.J. Lennarz
J.E. Levine
M.M. Lightfoote
D.M.J. Lilley
L.A. Loeb
W.F. Loomis
I.R. Mackay
J. Messing
S.R. Ojeda
D.W. Pfaff
A.R. Rees
E.J. Stanbridge
R.L. Stouffer
A. Tixier-Vidal
L.-C. Tsui
W.W. Vale
M.H.V. van Regenmortel
S.M. Weissman
R. Wu
- Methods in Enzymology Editors-in-Chief:
- J.N. Abelson
M.I. Simon
| 
