期刊名称:CURRENT BIOLOGY
期刊简介(About the journal)
投稿须知(Instructions to Authors)
编辑部信息(Editorial Board)
About the journal
Current Biology has established itself as a unique source of cutting-edge information in biology. With a broad scope of original research, incisive reviews and regular columns such as Quick Guide, Primers and Q&A articles, Current Biology has kept readers at the forefront of biological science for the past decade. Year after year, Cell Press journals are among the highest impact original research publications in their respective categories. They publish the most significant original research from the entire realm of biological science. Current Biology will take full advantage of the resources of Cell Press as it reaches new heights in biological publication.
Cutting-edge original research Rigorous review Rapid publication Broad scope Cross-discipline accessibility Published every two weeks, Current Biology delivers comprehensive coverage of all areas of biology.
Articles and Reports Significant papers published expeditiously that will affect your own research. Dispatches Leading researchers present timely analysis of the latest findings designed to inform and educate across all disciplines in the field.
Reviews In-depth discussion of topics of interest to the international science community.
Magazine Comprehensive coverage from the world of biology, including quick guides, incisive commentary and profiles of scientists and institutions in the news.
Instructions to Authors
Current Biology E-mail or fax us an abstract of your paper in advance of submission, and we will give you an editorial opinion of its suitability for Current Biology within 24 hours.
Scope Current Biology publishes Articles in any area of biology, provided that the research clearly represents an important advance of especially broad interest to biologists. Articles must be written and illustrated in a way that is appropriate for nonspecialist readers. Papers should normally occupy 4-10 pages of the journal; there are about 1,000 words or 35 references to a full page. Brevity is a virtue except when it is at the expense of essential information.
Current Biology also publishes Reports: short papers reporting results that are of genuinely broad interest but that for one reason or another do not make a sufficiently complete story to justify publication as a full Article. Authors are welcome to suggest that their paper is considered as a Report if they feel it is suitable for that format. Reports should occupy no more than four pages of the journal.
Reviewing and publication speed All submissions will be subject to an immediate editorial-screening process, usually in consultation with members of the editorial board or other advisers. Those that meet the criteria for consideration, as outlined above, will normally be sent to two reviewers who have agreed in advance to assess the paper rapidly, and the editors will make every effort to reach decisions on these papers within three weeks of the date of receipt. Accepted papers will be typeset more quickly if they are provided on a disk or sent by e-mail and if the instructions below are closely followed. Papers will be published in the next issue to go to press after proofs have been returned.
Presubmission enquiries Enquiries as to the suitability of a potential submission should be made in advance by e-mail to cbiol@current-biology.com, in which case an abstract that makes clear how the paper advances knowledge must be provided.
Submission Four copies of the manuscript should be submitted, preferably with a disk (see below), to: The Editors, Current Biology, Elsevier Science London, 84 Theobald's Road, London WC1X 8RR, UK. Upon prior consultation with the editors, electronic submission of the manuscript as a single PDF can also be arranged. Please provide telephone and fax numbers of the corresponding author and an e-mail address. If a manuscript is closely related to a paper in press or submitted elsewhere, four copies of this related paper should be provided along with the Current Biology submission. Suggestions for reviewers are welcome. There are no handling charges and no page charges. Authors will be charged $500 for the first colour figure and $250 for each additional colour figure to partially defray the cost of separating and printing colour figures.
Manuscript preparation All text must be double-spaced throughout. All pages must be numbered. Abbreviations should be defined the first time they are used, and a list of all abbreviations used should be provided. Spelling may be British or American, but not a mixture.
Manuscript organization Manuscripts of Articles should be divided into: Title page, Summary, Introduction, Results, Discussion, Conclusions, Experimental Procedures, Acknowledgements, References, Figure legends, Tables. Title page: should list names and addresses for all authors and should indicate the corresponding author. A running head of not more than 50 characters, including spaces, should be provided. Summary: should not exceed 250 words, should contain no references and must be structured into separate sections headed Background, Results, Conclusions. A sample is provided on the next page. Introduction: must be written from the standpoint of biologists without special knowledge, must clearly state (and, if helpful, illustrate) the background to the research and its aims, and should end with a brief statement of what has been achieved. Results and Discussion: may be combined or kept separate, and may be broken into subsections with short informative subheadings. Conclusions: must state clearly the main conclusions of the research and give a clear explanation of their importance and relevance. A summary illustration may be included. Experimental Procedures: should be divided into subsections. Acknowledgements: should be kept to a minimum. References: must be cited by number consecutively, in square brackets, in the text, followed by any that occur only in the tables or legends. Only papers that have been published or are in press may be included in the reference list; submitted manuscripts, personal communications (which can be included only with permission), abstracts and unpublished data should not be cited in the reference list, although they may be included in the text. Journal abbreviations follow Index Medicus/Medline; name up to ten authors, followed by et al. if more. References should be in Current Biology style, examples of which are printed on the next page. They will be typeset from disk only if they precisely follow this style. If not, they will be retyped and will require proofreading. Figure legends: should start with a title and should not exceed one page of text. Tables: should be titled and should not include vertical rules. Units: should be SI throughout (except liter and molar).
Manuscripts of Reports should be organized in the same way, with the following exceptions:
Summary: this should not be structured but should be written as a single paragraph that summarizes, in no more than 200 words, the background to the work, the new results to be reported and their implications; references should be cited in this paragraph. Introduction: there should be no separate Introduction section; the Summary should be followed by the main Results and Discussion section. Experimental Procedures: a separate section may not be necessary in a Report if methods can be described concisely and adequately in the text and figure/table legends.
Illustrations All figures and illustrations should be provided as high-quality, glossy prints in case we need to scan images; please do not write on the back of prints, but attach a label stating the author's names and figure number. Introductory and/or summary illustrations are encouraged. Photographs should be provided with a scale bar, if appropriate. Because minimal changes can be made to the figures after your manuscript is accepted, please ensure your figures are consistent with your article (e.g. abbreviations), and that any differences between figures and text are detailed. Please also ensure that your figures match our style as closely as possible. Different panels should be labeled in bold uppercase letters without parentheses (e.g., A, B, etc.). Please use Helvetica font for any text in your figures. Please can you also suggest what size you think your figures should be printed (single column images are 76.5 mm; one and a half column images are 101 mm; and double column images are 126-160 mm). We strongly encourage the electronic submission of figures. The publisher reserves the right to resize figures. See also a more detailed set of Guidelines for sending electronic figures or contact the managing editor.
Sending files On disk: we can accept 3.5 inch floppies (no 720K Mac disks please), 3.5 inch magneto-optical (128M or 256M), SyQuest cartridges (44M or 88M) and Zip disks. By email: e-mail text files under 1000k to cbiol@current-biology.com Please do NOT send figures by email. By FTP (this applies to accepted Articles and Reports only): By email: larger files can be sent by FTP to ftp.capcitypress.com Username: curbio Directory: figures Password: cirrus7 All data types should be transferred in binary (or MacBinary) mode. Please consult the editors for advice on appropriate FTP filenames.
We can accept most word-processor programs, in both PC and Macintosh formats. In all cases, also save the text as an ASCII file in case the word processing file is not translatable. Label the disk with the authors' names, the word processing program and version used, and the type of computer. In the case of a discrepancy between the disk and the manuscript, the latter will be taken as the definitive version.
To avoid problems, please take special care to:
?use carriage returns only to end headings and paragraphs, not to rearrange lines ?follow the precise style of Current Biology references ?use the ASCII character set if possible for special characters (e.g. Greek letters and mathematical symbols); if you are unable to reproduce a special character in your file, write it in red on the manuscript and we will insert the correct character.
Proofs Page proofs should be returned within 24 hours, preferably by fax. For clarity when faxing, please number your corrections on the page proofs, and list them on an accompanying sheet. You are allotted one correction per two article pages; there will be a $25 charge for each correction above this number.
Offprints/reprints Extra offprints can be ordered before the press date. Reprints may be purchased at a later stage but are more expensive.
Policies Publication in Current Biology implies that all authors of the paper have read and agreed to its content, and that readily replaceable material described in the paper will be freely distributed to academic colleagues. Nucleic acid sequences, protein sequences and atomic coordinates should be deposited in an appropriate database in time for the accession number to be included in the paper. Correspondence concerning papers published in Current Biology is encouraged. Correspondence containing data or scientific argument is subject to review.
-------------------------------------------------------------------------------- Current Biology Article sample abstract Background: In eukaryotic cells, there is a complex system of traffic between distinct vesicular compartments, and a number of the biochemical components of this system have been identified. There is evidence that small GTPases related to the Ras family, particularly members of the Rab family, are important in directing membrane traffic. We have previously reported evidence that Rab5 is involved in the fusion of early endosomes with each other, but the precise scope of the function of Rab5 in vivo has not been defined.
Results: To investigate the function of Rab5 in vivo we overexpressed in baby hamster kidney cells either wild-type Rab5 or a mutant form of Rab5 defective in GTP binding. Overexpression of the mutant Rab5 reduced the rate of endocytosis by 50% without significantly affecting the rate of recycling, and led to a drastic change in the morphology of early endosomes. Surprisingly, overexpression of wild-type Rab5 accelerated the uptake of endocytic markers and led to the appearance of atypically large early endosomes.
Conclusions: We conclude that Rab5 is a rate-limiting component of the machinery regulating the kinetics of membrane traffic in the early endocytic pathway.
Current Biology reference style
Journal 1. Holmes, S., and Watson, J. (1993). Identification of the function of the moriarty gene product. Curr. Biol. 3, 121-129.
Journal supplement 2. Holmes, S., and Watson, J. (1993). Identification of the function of the moriarty gene product. Curr. Biol. Suppl. 2, 121-129.
Book 3. Doyle, A.C. (1991). Biological Mysteries Solved, Second Edition, (London: Science Press).
Book chapter 4. Holmes, S., and Watson, J. (1991). Identification of the function of the moriarty gene product. In Biological Mysteries Solved, A.C. Doyle, ed. (London: Science Press), pp. 56-62.
Editorial Board
Michael Akam (UK) Frederick W. Alt (USA) Angelika Amon (USA) Avi Ashkenazi (USA) Cori Bargmann (USA) Ben A. Barres (USA) Wolfgang Baumeister (Germany) Seth Blair (USA) Henry R. Bourne (USA) Bruce Bowerman (USA) Oliver Braddick (UK) Jeremy Brockes (UK) John Brookfield (UK) Steve Brown (UK) Brian Charlesworth (UK) Michael J. Clague (UK) Paul Clapham (UK) Holly Cline (USA) Louise Cramer (UK) Jason Cyster (USA) John Diffley (UK) Jennifer A. Doudna (USA) Julian Downward (UK) Eric Fearon (USA) James E. Ferrell, Jr. (USA) Brett Finlay (Canada) Claire M. Fraser (USA) Matthew Freeman (UK) Ronald N. Germain (USA) Michael Glotzer (Austria) David B. Goldstein (UK) Christopher Goodnow (Australia) Dan Gottschling (USA) Michael R. Green (USA) Barry Gumbiner (USA) Gunther Hammerling (Germany) Ulrich Hartl (Germany) Michael Hengartner (Switzerland) Tasuku Honjo (Japan) Anya Hurlbert (UK) Philip Ingham (UK)
Robert Insall (UK) Robin Irvine (UK) Steve Jacobsen (USA) Tom Jessell (USA) Lawrence C. Katz (USA) Juergen Knoblich (Austria) Angus Lamond (UK) Ottoline Leyser (UK) Tomas Lindahl (UK) Dan Littman (USA) Nikos K. Logothetis (Germany) Andrew McMichael (UK) Eve Marder (USA) Diane Mathis (USA) Iain W. Mattaj (Germany) Elliot M. Meyerowitz (USA) Tim Mitchison (USA) Andrew Murray (USA) Venkatesh Murthy (USA) Sean Munro (UK) Howard Nash (USA) Jeff Nye (USA) Ole H. Petersen (UK) Nikolaus Pfanner (Germany) Thomas D. Pollard (USA) David H. Raulet (USA) Anne Ridley (UK) Keith Roberts (UK) Joel H. Rothman (USA) Chris Rudd (USA) Michael Shadlen (USA) Lila Solnica-Krezel (USA) Charles Stevens (USA) Caro-Beth Stewart (USA) David van Vactor (USA) Clare Waterman-Storer Jim Woodgett (Canada) Mitsuhiro Yanagida (Japan)
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