期刊名称：TOXICOLOGY IN VITRO
 期刊简介(About the journal)
投稿须知(Instructions to Authors)
编辑部信息(Editorial Board)
About the journal
Toxicology in Vitro
|
Toxicology in Vitro publishes original research papers and reviews on the application and use of in vitro systems for assessing or predicting the toxic effects of chemicals and elucidating their mechanisms of action. These in vitro techniques include utilizing cell or tissue cultures, isolated cells, tissue slices, subcellular fractions, transgenic cell cultures, and cells from transgenic organisms, as well as in silico modelling. The Journal will focus on investigations that involve the development and validation of new in vitro methods, e.g. for prediction of toxic effects based on traditional and in silico modelling; on the use of methods in high-throughput toxicology and pharmacology; elucidation of mechanisms of toxic action; the application of genomics, transcriptomics and proteomics in toxicology, as well as on comparative studies that characterise the relationship between in vitro and in vivo findings. The Journal strongly encourages the submission of manuscripts that focus on the development of in vitro methods, their practical applications and regulatory use (e.g. in the areas of food components cosmetics, pharmaceuticals, pesticides, and industrial chemicals |
|
Audience
Academic, governmental and industrial laboratories using in vitro techniques.
Abstracting / Indexing
|
BIOSIS
Chemical Abstracts
Current Contents/ISI/BIOMED Database
Current Contents/Life Sciences
Current Contents/SciSearch Database |
Current Contents/Science Citatation Index
EMBASE
Elsevier BIOBASE
Research Alert
Toxicology Abstracts |
Instructions to Authors
General Information
The Journal's main purpose will be the publication of papers reporting and interpreting original toxicological research involving the application or development of in vitro techniques. Brief Communications documenting important new findings warranting expeditious publication will also be considered, as will concise interpretative Reviews of toxicological topics of contemporary significance. Letters to the Editor will be limited to comments on contributions already published in the Journal; if a letter is accepted, a response (for simultanous publication) will be invited from the authors of the original contribution.
Submission of a paper will be held to imply that it reports original unpublished research, that it is not under consideration for publication elsewhere and that, if accepted for Toxicology in Vitro, it will not be published again, either in English or in any other language, without the Editors' consent.
Three copies of the manuscript should be submitted, one being the original, accompanied by a signed covering letter providing, if possible, a fax number. Manuscripts should be sent to: Professor D. Acosta (USA and Canada); Professor B.J. Blaauboer (Europe, except UK); Ms S. Hill (UK and all others); at the following addresses:
PROFESSOR DANIEL ACOSTA, University of Cincinnati, College of Pharmacy, 3223 Eden Avenue, Cincinnati, OH 45267-0004, USA
PROFESSOR BAS J. BLAAUBOER, Institute for Risk Assessment Sciences (IRAS), Division of Toxicology (RITOX), Utrecht University, PO Box 80.176, 3508 TD Utrecht, The Netherlands
MS S. HILL, Managing Editor, BIBRA International, Woodmansterne Road, Carshalton, Surrey SM5 4DS, UK
Manuscript Format
Manuscripts should be written in clear and concise English; incomprehensible submissions will be returned to authors for revision. Manuscripts should be typed on one side of the paper only and double spaced throughout, with at least 2.5-cm margins. All pages must be numbered, including the Title Page, which should carry the title of the paper, the surnames and initials of the authors, the names and address of the institutions where the work was done (with the affiliation of each author clearly indicated) and a short running title not exceeding 45 letters and spaces. Titles consisting of declarative or interrogative sentences are not acceptable. Provision of telephone and or/fax numbers will assist the processing of contributions.
Manuscripts of original papers should be organized into the following sections, each commencing on a separate sheet:
Abstract-a self-contained summary of the objectives, results and significance of the study, not exceeding 200 words. Uninformative sentences such as "the significance of the results is discussed" are not acceptable.
Introduction-a concise and clear statement on the background, purposes and significance of the work.
Materials and Methods-a detailed descripton of the experimental design and of any new or improved methods. Well-established methods and techniques may be identified by reference only.
Results-presented concisely with the aid of tables or figures where appropriate. Duplication between this section and the Discussion must be avoided.
Discussion-a succinct interpretation of the data. Extensive literature reviews and highly speculative comments are discouraged.
Acknowledgements-providing recognition of sources of funding and donations of materials, and including any thanks the authors may wish to accord for advisory, technical or other assistance, since authorship should be limited to those who have made a major contribution to the study and to the preparation of the paper. Authors are advised to obtain approval for the wording of any acknowledgement from those whose help is noted.
References-listed strictly in alphabetical order and including the names of all authors of the cited work. References to published papers should provide authors' names and initials, year of publication, full title of the paper, title of the journal (in full), volume number, and the first and last page numbers of the paper:
e.g. Wright A., Cowie H., Gormley I.P. and Davies J.M.G. (1986) The in vitro Cytotoxicity of asbestos fibres: 1. P388D1 cells. American Journal of Industrial Medicine 9, 371-384.
References to books should include authors' names and initials, year of publication, title, edition, appropriate page number(s) and name and location of the publisher:
e.g. Foussereau J., Benezra C. and Maibach M. (1982) Occuptational Contact Dermatitis. Clinical and Chemical Aspects. p. 277. Munksgaard, Copenhagen.
For multi-author books, the names and initials of the relevant authors, year of publication, title of the relevantchapter, title of the book, names and initials of all editors, numbers of first and last pages of the cited chapter and name and location of the publisher should be given:
e.g. Mather J.P. and Phillips D.M. (1984) Primary culture of testicular somatic cells. In Methods for Serum-free Culture of Cells of the Endocrine System. Edited by D.W. Barnes, D.A. Sirbasku & G.H. Sato. pp. 29-45. Alan R. Liss, New York.
Citations of references in the text should give the surname(s) of the author(s), together with the year of publication. For references with more than two authors, the name of the first followed by et al. should be cited. For papers with the same author(s) and year, the references should be distinguished in the text and reference list by the letters a, b etc. following the year (but still in alphabetical order). Authors names must not be typed in upper case letters in either text or reference list.
References may be listed if they are 'in press', but the journal that has accepted the paper for publication must be identified. Submitted papers or papers in preparation should not be listed; such work should be mentioned in the text only, as 'unpublished data' or 'personal communication' (with surnames, initials and year).
These sections should be followed by the tables in numerical order, each on a separate sheet, and finally by a typed list of the legends to the figures (see below).
Electronic submission
Authors should submit an electronic copy of their paper with the final version of the manuscript. The electronic copy should match the hardcopy exactly. Always keep a backup copy of the electronic file for reference and safety. Full details of electronic submission and formats can be obtained from http://authors.elsevier.com.
Submission on Disk after Acceptance for Publication
Elsevier Science now publishes all manuscripts using electronic production methods and strongly encourages submission on disk. Please send the electronic files of your article along with the hardcopy of the accepted version. To ensure fast and easy processing of your submission, please adhere to the following guidelines:
1. Save text and graphics on separate disks.
2. Label all disks with your name, a short version of the article title, the journal to be published in, and the filenames. Please also include details of the software and platform (PC, Mac, UNIX, etc) used to create your files.
3. Ensure that the files on the disk match the hardcopy exactly. In cases of a discrepancy, the hardcopy version will be used as the definitive version.
Tables and Figures
These should be intelligible without reference to the text and should be planned to fit the page size of the Journal. Tables and figures should be numbered, in arabic numerals, in the sequence in which they are mentioned in the text. The same data may not be reproduced in both a table and a figure. Each table must have a title and on each column there should be a heading that clearly identifies the data therein. Illustrations and diagrams should be kept to a minimum; the figure number must appear only on the reverse side, together with the author's name and an arrow marking the top. Three copies of any half-tones (unmounted and on glossy paper) are required; for line drawings, an original (in black drawing ink or computer laser output on good quality paper) or a glossy print is required for reproduction, together with two clear photocopies for the referees. No information that can be included in the legend should appear on the figure and the following standard symbols are preferred for line drawings: (closed triangle), (open triangle), (closed square), (open square), (closed circle), (open circle), (open circle with a dot in the middle), +, (open diamond).
The legends for photomicrographs must state the staining method and magnification. Authors should bear in mind that the figures they submit may be subjected to photographic reduction. The cost for illustrations in colour will be the responsibility of the contributor(s) (an estimate may be obtained from the Editorial Office at BIBRA).
If figures that have already been published under copyright are to be reproduced in the Journal (e.g. in reviews), copies of letters from the first publisher and the original author giving permission for such reproduction must always accompany the submitted manuscript.
Footnotes
These should include the definitions of any abbreviations used in the text and any author's current address, if different from that on the title page. Other footnotes, as distinct from literature references, should be avoided in the text as far as possible. When they are essential, they should be identified by the symbols * ¡ì in that order. All the footnotes except those for tables should be typed on a separate sheet, with an indication of the manuscript page to which the footnote refers.
Nomenclature
The metric system is the standard for all measurements. Test chemicals and enzymes must be clearly identified, wherever possible with the aid of CAS Registry and EC numbers.
Abbreviations
These should be used sparingly; they should be defined when first used in the paper but also listed in alphabetical order under Abbreviations as a footnote to the title page (see above).
Page proofs
These will be sent to the first-named author for correction unless an alternative recipient is named on the submitted manuscript. They should be retuend to the Editorial Office at BIBRA within 48 hours. Corrections to the proofs must be limited to printers' errors only.
Reprints
A reprint order form will accompany the page proofs. This must be returned to the Editorial Office at BIBRA with the proofs. No payment should be included with the order as an invoice will be sent later
Editorial Board
Editors:
Daniel Acosta, Dean, University of Cincinnati, College of Pharmacy, 3223 Eden Avenue, PO Box 670004, Cincinnati, OH 45267, USA
Bas J. Blaauboer, Institute for Risk Assessment Sciences (IRAS), Division of Toxicology (RITOX), Utrecht University, PO Box 80.176, 3508 TD Utrecht, The Netherlands
Associate Editor:
Stuart E. Jaggers, BIBRA International, Woodmansterne Road, Carshalton, Surrey SM5 4DS, UK
Review Editor:
Daniel Dietrich PhD, Faculty of Biology, University of Konstanz, Konstanz, Germany Email: Daniel.Dietrich@uni-konstanz.de
Editor Emeritus:
Iain F.H. Purchase, 79 Knutsford Road, Wilmslow, Cheshire SK9 6JH, UK
Managing Editor:
S. Hill, TNO BIBRA International, Woodmansterne Road, Carshalton, Surrey, SM5 4DS, UK
International Editorial Board:
J.C. Barrett, NIEHS, Research Triangle Park, NC, USA
D. Benford, University of Surrey, Guildford, UK
J. Bradlaw, FDA, Laurel, MD, USA
N.A. Brown, St George's Hospital & Medical School, London, UK
E. Chacon, Cedra Corporation, Austin, TX, USA
R.D. Combes, FRAME, Nottingham, UK
J. Davila, Searle Company, Skokie, IL, USA
D. Doolittle, R.J. Reynolds, Winston-Salem, NC, USA
R. Fahrig, Fraunhofer-Institut f¨¹r Toxikologie und Aerosol-Forschung, Hannover, Germany
T.J.B. Gray, Sanofi Winthrop Research Centre, Alnwick, UK
A. Guillouzo, Hopital de Pontchaillou, Rennes, France
G. Hard, American Health Foundation, Valhalla, NY, USA
G.J.M.J. Horbach, N.V. Organon, Oss, The Netherlands
D. Lovell, Pfizer Central Research, Kent, UK
P. Maier, Swiss Federal Institute of Technology and University of Zurich, Schwerzenbach, Switzerland
F. Marano, Universit¨¦ Paris 7, France
C.A. McQueen, University of Arizona, Tucson, AZ, USA
R. Melchert, University of Arkansas for Medical Sciences, Little Rock, AR, USA
M. Nagao, National Cancer Center Research Institute, Tokyo, Japan
K. Ramos, Texas A&M University, College Station, TX, USA
R. Rodriguez, Oregon State University, Corvallis, OR, USA
V. Rogiers, Vrije Universiteit Brussel, Brussels, Belgium
A.A.J.J.L. Rutten, Intervet Pharma R & D SA, Beaucouze, France
N. Stacey, Schein Bayer Pharmaceuticals Australia, Pymble, Australia
K.A. Stitzel, The Procter and Gamble Company, Cincinnati, OH, USA
H. Tahti, University of Tampere, Tampere, Finland
R. Ulrich, Pharmacia & Upjohn Inc., Kalamazoo, MI, USA
E. Walum, Pharmacia & Upjohn AB, Stockholm, Sweden
A.A. Welder, University of Oklahoma, OK, USA
F. Zucco, Consiglio Nazionale Delle Ricerche, Rome, Italy
P.A. Botham, Zeneca Central Toxicology Laboratory, Alderley Park, Macclesfield, Cheshire, SK10 4TJ, UK
|
