期刊名称：JOURNAL OF CLINICAL ONCOLOGY ISSN： 0732-183X 版本： SCI-CDE 出版频率： Fortnightly 出版社： LIPPINCOTT WILLIAMS & WILKINS, TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, USA, PA, 19103   出版社网址： http://jco.ascopubs.org/ 期刊网址： http://jco.ascopubs.org/ 影响因子： 44.544 主题范畴： ONCOLOGY 期刊简介(About the journal)    投稿须知(Instructions to Authors)    编辑部信息(Editorial Board)    About the journal  The Journal of Clinical Oncology is the primary source of scientific discourse for the American Society of Clinical Oncology. In print, and in electronic media, the Journal¡¯s goal is to publish the highest quality manuscripts dedicated to clinical research. Original Reports remain the focus of the Journal, but this scientific communication is enhanced by appropriately selected editorials, reviews, and occasional pieces that relate to the care of patients with cancer. Journal of Clinical Oncology (ISSN 0732-183X) is published 24 times a year, twice monthly, by American Society of Clinical Oncology. Periodical postage is paid at Alexandria, VA, and at additional mailing offices.   Instructions to Authors MANUSCRIPT PREPARATION GUIDELINES Submission Cover Sheet Potential Conflict of Interest Disclosure Form Diskette Guidelines/Transmittal Form Title Page Abstract Text Figures Tables Keywords References Reference Style Appendices/Acknowledgements Disk Requirements An original and four complete copies of the manuscript must be submitted, for a total of FIVE COPIES. Manuscripts must be printed, double- or triple-spaced on good quality, standard size white paper with margins of at least 1 inch. Pages must be numbered, starting with the title page. The Submission Cover Sheet and Potential Conflict of Interest Disclosure Form, available in every issue of the Journal, upon request from the Editorial Office, or at www.jco.org, must be filled out and sent with all submissions. A computer disk is required with all submissions, whether the manuscript is new or revised. The Diskette Transmittal Guidelines/Form must accompany the disk. These forms may be downloaded from this web site in PDF format by clicking the appropriate link. The forms may be photocopied and disseminated as needed. Title Page The first page of the manuscript should contain the following information: (1) title of the report; (2) a list of no more than 20 authors' names; (3) name(s) of the institution(s) at which the work was done; (4) acknowledgments of research support; (5) name, address, phone, fax and e-mail address* information of the corresponding author; and (6) a running head that is no more than 45 characters; and (7) list where and when the study has been presented in part elsewhere, if applicable. *Please note, an e-mail address of the corresponding author is required with ALL submissions. Abstract The second page of the manuscript is to contain an abstract of 250 words or less. Abstracts must be organized and formatted according to the following headings: (1) PURPOSE, (2) PATIENTS AND METHODS (or MATERIALS AND METHODS, METHODS, or similar heading, following the structure of the text), (3) RESULTS, and (4) CONCLUSION. Authors may use DESIGN instead of PATIENTS AND METHODS in abstracts of review articles. Text Research manuscripts must have the following sections clearly identified: INTRODUCTION, PATIENTS AND METHODS (or MATERIALS AND METHODS, METHODS, or similar heading appropriate for the manuscript), RESULTS, and DISCUSSION. A summary should not be included at the end of the text. The body of the manuscript should be written as concisely as possible and should not exceed 3500 words. The Journal adheres to the style guidelines set forth by the International Committee of Medical Journal Editors. Please refer to www.icmje.org for more information. Figures Figures must be cited in order in the text using Arabic numerals. A uniform font and type size is required for all figures: Helvetica font and type size between 8 and 12 point. All figures must be submitted in triplicate sorted sets (one per manuscript), each of which is individually identified on the back by the corresponding author's name and figure number. Electron micrographs, halftones, and photographs must be submitted as glossy prints; line drawings, charts, and graphs may be submitted as either glossy prints or laser printer-generated figures. Contributors will pay all costs of printing color photographs. The publisher will contact the corresponding author regarding the exact cost. Figures are generally reduced in size for publication. Crop marks should be indicated for those figures that can be cropped. To maintain legibility, all numbers, letters, and symbols should be large enough originally so that when reduced they will remain at least 1/12 inch (2 mm) high (ie, approximately the same size as used for this line of type). Do not mount glossy figures on cardboard or other paper. Figures not properly prepared will be returned to the contributor for revision or will be re-lettered by the printer at a cost charged to the contributor. Figure legends are required and should be typewritten or printed double-spaced on a separate sheet. All relevant and explanatory information extraneous to the actual figure should be included in the text. Figure legends may not exceed 45 words. If a figure(s) has been reprinted, a letter of permission from the copyright holder must be provided by the corresponding author upon acceptance of the manuscript. The accepted manuscript will not be published without the necessary granted permission. For more information on uniform figure submission requirements please refer to http://cpc.cadmus.com/da/. Tables Tables must be cited chronologically in the text using Arabic numbers. Each numbered table should be typed on a separate sheet, with a title and a legend that includes definitions of abbreviations that have been used in the table but not in the text. If a table(s) has been reprinted, a letter of permission from the copyright holder must be provided by the corresponding author upon acceptance of the manuscript. Keywords On the "Manuscript Submission Cover Sheet," authors are asked to provide keywords relating to the manuscript's topic for indexing purposes. Limit your suggestions to no more than six words. References References are to be compiled at the end of the text and must be listed and numbered in the order in which they are cited in the text. They should be typewritten or printed double-spaced, under the heading REFERENCES. Abbreviations for titles of medical periodicals should conform to those used in the latest edition of Index Medicus and on MEDLINE. The "List of Journals Indexed in Index Medicus" includes the latest abbreviations and can be obtained from the Superintendent of Documents, US Government Printing Office, Washington, DC 20402, or at www.nlm.nih.gov/tsd/serials/lji.html. Inclusive page numbers must be cited in the reference. When a reference is an abstract, editorial, or published letter, it must be identified as such in parentheses at the end of the reference. When a reference is a personal communication, it should be included in the body of the text and not cited in the reference list. Reference Style Journal article, one, two, or three authors: 1. Dolan ME, Pegg AE: O6-Benzylguanine and its role in chemotherapy. Clin Cancer Res 8:837-847, 1997 Journal article, more than three authors: 2. Knox S, Hoppe RT, Maloney D, et al: Treatment of cutaneous T-cell lymphoma with chimeric anti-CD4 monoclonal antibody. Blood 87:893-899, 1996 Journal article in press: 3. Scadden DT, Schenkein DP, Bernstein Z, et al: Combined immunotoxin and chemotherapy for AIDS-related non-Hodgkin's lymphoma. Cancer (in press) Supplement: 4. Brusamolino E, Orlandi E, Morra E, et al: Analysis of long-term results and prognostic factors among 138 patients with advanced Hodgkin's disease treated with the alternating MOPP/ABVD chemotherapy. Ann Oncol 5:S53-S57, 1994 (suppl 2) Book with a single author(s): 5. Woodruff R: Symptom Control in Advanced Cancer. Victoria, Australia, Asperula Pty Ltd, 1997, pp 65-69 Chapter in a multi-authored, edited book: 6. Seykora JT, Elder DE: Common acquired nevi and dysplastic nevi as precursor lesions and risk markers of melanoma, in Kirkwood JM (ed): Molecular Diagnosis and Treatment of Melanoma. New York, NY, Marcel Dekker, 1998, pp 55-86 Abstract: 7. Jurgens H, Cassoni A, Dunst J, et al: Report from the European Intergroup Cooperative Ewing's Sarcoma Study (EICESS 92). Med Pediatr Oncol 27:264, 1996 (abstr) Editorial: 8. Larson SM: Cancer or inflammation? A Holy Grail for nuclear medicine. J Nucl Med 35:1653-1655, 1994 (editorial) Published Letter: 9. Longo DL: Interferon toxicity worse in retrospect; Impact on Q-TWiST? J Clin Oncol 16:3716, 1998 (letter) Conference/Meeting Presentation: 10. Dupont E, Riviere M, Latreille J, et al: Neovastat: An inhibitor of angiogenesis with anti-cancer activity. Presented at Am Assoc Cancer Res Special Conference Angiogenesis and Cancer, Orlando, FL, January 24-28, 1998 Internet Resource: 11. Health Care Financing Administration: Bureau of data management and strategy from the 100% MEDPAR inpatient hospital fiscal year 1994: All inpatients by diagnosis related groups, 6/95 update. Http://www.hcfa.gov/a1194drg.txt Appendices/Acknowledgments Due to page constraints, the Journal is unable to publish appendices used to acknowledge study participants or contributors. All appendices used as an Acknowledgment section will be published in the online version only. A reference to the appendices being available online will be in the print version. Acknowledgments at the end of the manuscript should contain no more than 30-50 words. Disk Requirements A diskette is required with all submissions, whether the manuscript is new or revised. A manuscript submission will not be processed without a disk. The ¡°Diskette Transmittal Form,¡± available upon request from the Editorial Office or at www.jco.org, should be completed and submitted with the disk. A copy of the guidelines for preparing and submitting a diskette is also available upon request from the Editorial Office and at www.jco.org. ADDITIONAL INFORMATION Copyright Form In compliance with the requirements of the insurance carrier, the authors will be requested, upon acceptance of the manuscript, to sign a statement confirming that the manuscript "contains no material the publication of which violates any copyright or other personal or proprietary right of any person or entity." Page Proofs Contributors are provided with page proofs and are asked to proofread them for typesetting errors. Authors are required to review their page proofs carefully. Minor changes are allowed, but authors will be charged for excessive alterations. The Editor-in-Chief must approve all excessive alterations, which may delay publication of the manuscript. Page proofs not returned by the publisher¡¯s deadline will result in a delay in the manuscript¡¯s publication date. The Journal employs electronic transmittal of proofs. When galley proofs are available for downloading, the corresponding author will receive an e-mail notification with a password and web address where the proofs may be downloaded into a .pdf file and printed. Paper copies will not be sent out. Corrections to page proofs must be returned via mail or fax within 48 hours. Reprints An order form, showing cost of reprints, is sent with the page proofs so that authors may order reprints before publication. Reprints may be ordered after publication but at a higher cost. The reprint order form must be returned within 48 hours of receipt with the page proofs, even if reprints are not ordered. Permissions Authors submitting a manuscript do so on the understanding that if it is accepted for publication, copyright of the article, including the right to reproduce the article in all forms and media, shall be assigned exclusively to the American Society of Clinical Oncology (ASCO). If any portion of an article submitted for consideration (i.e., figure or table) has been previously published, acknowledge the original source and submit written permission from the copyright holder to reproduce the material. Permission is required regardless of authorship or publisher, except for documents in the public domain. ASCO will not refuse any reasonable request by the author for permission to reproduce any of his or her contributions to the Journal. Digital Object Identifier (DOI) The Digital Object Identifier (DOI) system is a framework for identifying and exchanging intellectual property in the digital environment. The system was designed for managing intellectual content, linking customers with suppliers, and enabling automated copyright management for all types of media. A DOI can point website users, Journal subscribers, and members directly to online articles cited in Journal references. It is different from commonly used pointers such as the URL, Uniform Resource Locator, because it identifies an object, not the place where the object is located. For instance, if an article were to be Published Ahead of Print, the DOI provides a way to locate and cite the article prior to printed publication. In addition to providing digital identification, the DOI will enable comprehensive reference linking through CrossRef (for more information go to www.crossref.org). In order to provide digitial protection, we assign a Digitial Object Identifier (DOI) to all published articles. The DOI is located at the bottom of the first page of each published article. CiteTrack The CiteTrack service will alert you by e-mail whenever new content in Journal of Clinical Oncology or a participating journal is published that matches criteria based on keywords, authors or articles that are important to you. Keyword alerts will notify you when new content is published containing keywords specified by you. Author alerts will notify you when key authors of interest to you publish a new paper. Article alerts will notify you when a paper of interest to you is referenced by another paper or letter. This is a free service. To sign up now, please click here. eTOCs The eTOC service allows anyone who registers their e-mail address to be notified via e-mail when new content goes online. You may choose to receive any or all of the following: Notification that a new issue of Journal of Clinical Oncology is online. Complete table of contents for new issues. Special announcements from ASCO. Editorial Board Editor Roster EDITOR-IN-CHIEF Daniel G. Haller, MD, Philadelphia, PA Associate Editors George J. Bosl, MD, New York, NY Stephen A. Cannistra, MD, Boston, MA Bruce D. Cheson, MD, Washington, DC S. Gail Eckhardt, MD, Denver, CO Arlene A. Forastiere, MD, Baltimore, MD Patricia A. Ganz, MD, Los Angeles, CA David M. Khayat, MD, PhD, Paris, France Theodore S. Lawrence, MD, PhD, Ann Arbor, MI Mark N. Levine, MD, Hamilton, Canada Michael P. Link, MD, Stanford, CA Nicholas J. Petrelli, MD, Newark, DE Mark J. Ratain, MD, Chicago, IL Consultant Editors Colin B. Begg, PhD--Biostatistics Stephen A. Cannistra, MD--Biology of Neoplasia Charles L. Loprinzi, MD--The Art of Oncology Arthur T. Skarin, MD--Diagnosis in Oncology H. Samuel Wieand, PhD--Biostatistics JCO Spanish Edition Editor, Franco M. Muggia, MD, New York, NY Associate Editor, Roman Pérez-Soler, MD, Bronx, NY JCO Chinese Edition Editor, Raymond Liang, MD, Pokfulam, Hong Kong JCO Polish Edition Editor, Maciej Krzakowski, MD, Warsaw, Poland Editors-in-Chief Emeriti Joseph R. Bertino, MD, New Brunswick, NJ George P. Canellos, MD, Boston, MA Publisher Robin Bodishbaugh Administrative Assistant Barbara Alexander Managing Editor Ken G. Kornfield Senior Editorial Assistant Glenn Landis Editorial Assistants Seraphim Arnow Ryan Krausmann Melissa Nunnally Michael Ray Intellectual Property Rights Manager Frances Kuecker Marketing Program Manager Cecelia Huffman Circulation Manager Lucia Tayiel Program Assistants Shoni Carver Tanya Cervone Marketing Assistant Christina Taylor Director of Production Victoria Vaughn Journal Administrators Dana Monzi Denise Shields Copy Editors John Bell Juana Llorens Nora Myhre-De Stefano Proofreader Famin Ahmed Production Assistant Alicia Richardson Administrative Assistant Todd Hopkins Executive Editor Deborah Whippen Editorial & Publications Offices 330 John Carlyle Street Suite 300 Alexandria, VA 22314 Editorial Office Phone: 703-797-1900 Fax: 703-684-8720 E-mail: jco@asco.org Publications Office Phone: 703-519-1430 Fax: 703-518-8155 E-mail: jcoservice@asco.org Editorial Board Neil K. Aaronson, PhD, Amsterdam, The Netherlands James Abbruzzese, MD, Houston, TX Neil Abramson, MD, Jacksonville, FL David Adelstein, MD, Cleveland, OH Alex A. Adjei, MD, PhD, Rochester, MN D. Craig Allred, MD, Houston, TX James Anderson, PhD, Omaha, NE Michael A. Andrykowski, PhD, Lexington, KY Deborah Kay Armstrong, MD, Baltimore, MD Carlos Luis Arteaga, MD, Nashville, TN Dean F. Bajorin, MD, New York, NY Jose Baselga, MD, Barcelona, Spain William M. Bensinger, MD, Seattle, WA James A. Bonner, MD, Birmingham, AL Michael A. Bookman, MD, Philadelphia, PA Julienne E. Bower, PhD, Los Angeles, CA Barbara Ann Burtness, MD, New Haven, CT Michael A. Carducci, MD, Baltimore, MD Peter Carroll, MD, San Francisco, CA Michaele C. Christian, MD, Bethesda, MD Melody Cobleigh, MD, Chicago, IL Susan L. Cohn, MD, Chicago, IL Joseph M. Connors, MD, Vancouver, Canada Mary B. Daly, MD, PhD, Philadelphia, PA Anthony V. D'Amico, MD, PhD, Boston, MA Christopher K. Daugherty, MD, Chicago, IL Aimery de Gramont, MD, Paris, France Angela M. DeMichele, MD, Philadelphia, PA Pieter H. M. De Mulder, MD, Nijimegen, the Netherlands Christopher Desch, MD, Richmond, VA Ronald de Wit, MD, Rotterdam, The Netherlands Jean-Yves Douillard, MD, PhD, Saint Herblain, France Glenn Dranoff, MD, Boston, MA Merrill Egorin, MD, Pittsburgh, PA Matthew Ellis, MD, PhD, Durham, NC Paul Ellis, MD, London, UK Ezekiel J. Emanuel, MD, PhD, Bethesda, MD John K. Erban, MD, Boston, MA Elihu Estey, MD, Houston, TX Howard A. Fine, MD, Bethesda, MD Sophie D. Fossa, MD, Oslo, Norway Thomas F. Gajewski, MD, PhD, Chicago, IL Judy E. Garber, MD, Boston, MA Luca Gianni, MD, Milan, Italy Eli Glatstein, MD, Philadelphia, PA Robert Glynne-Jones, MD, Northwood, UK Richard M. Goldberg, MD, Chapel Hill, NC Pamela J. Goodwin, MD, Toronto, Canada Steven D. Gore, MD, Baltimore, MD Stephanie Green, PhD, Seattle, WA Bruce Haffty, MD, New Haven, CT Linda C. Harlan, MD, Bethesda, MD Peter G. Harper, MD, London, UK James A. Hayman, MD, Ann Arbor, MI Manuel Hidalgo, MD, Baltimore, MD Wolfgang Hiddemann, MD, PhD, Munich, Germany Dieter Hoelzer, MD, PhD, Frankfurt, Germany Paulo M. Hoff, MD, Sao Paulo, Brazil Gary R. Hudes, MD, Philadelphia, PA Clifford Hudis, MD, New York, NY Melissa M. Hudson, MD, Memphis, TN Stephen Hunger, MD, Gainesville, FL David Ilson, MD, New York, NY Patrick G. Johnston, MD, PhD, Belfast, N. Ireland Morton S. Kahlenberg, MD, San Antonio, TX Margaret Kemeny, MD, Jamaica, NY Vijay Khatri, MD, Sacramento, CA Merrill S. Kies, MD, Houston, TX Eric A. Klein, MD, Cleveland, OH Susan J. Knox, MD, PhD, Stanford, CA William G. Kraybill, MD, Buffalo, NY Mark G. Kris, MD, New York, NY Matthew Kulke, MD, Boston, MA Larry E. Kun, MD, Memphis, TN John Leonard, MD, New York, NY Benjamin D.L. Li, MD, Shreveport, LA Scott M. Lippman, MD, Houston, TX Mitchell Machtay, MD, Philadelphia, PA Jennifer Malin, MD, Los Angeles, CA David G. Maloney, MD, PhD, Seattle, WA Eleftherios P. Mamounas, MD, Canton, OH Dominique Maraninchi, MD, PhD, Marseille, France Neyssa Marina, MD, Stanford, CA Maurie Markman, MD, Cleveland, OH Katherine K. Matthay, MD, San Francisco, CA Cornelius McGinn, MD, Ann Arbor, MI Richard P. McQuellon, PhD, Winston Salem, NC Paul A. Meyers, MD, New York, NY Hironobu Minami, MD, Kashiwa, Japan Bruce D. Minsky, MD, New York, NY Robert J. Motzer, MD, New York, NY Timothy J. Moynihan, MD, Rochester, MN Barbara A. Murphy, MD, Nashville, TN Moise Namer, MD, Nice, France Susan O'Brien, MD, Houston, TX Herbert M. Pinedo, MD, PhD, Amsterdam, The Netherlands Elizabeth Poplin, MD, New Brunswick, NJ Kathleen I. Pritchard, MD, Toronto, Canada Ching-Hon Pui, MD, Memphis, TN Gregory Reaman, MD, Washington, DC John A. Ridge, MD, PhD, Philadelphia, PA Laurent Rivory, PhD, Camperdown, Australia Leslie L. Robison, PhD, Minneapolis, MN Miguel Rodriguez-Bigas, MD, Houston, TX Ama Rohatiner, MD, London, UK Kenneth J. Russell, MD, Seattle, WA Gordon J. S. Rustin, MD, Middlesex, UK Stephen E. Sallan, MD, Boston, MA Martin G. Sanda, MD, Ann Arbor, MI Yasutsuna Sasaki, MD, Kashiwa, Japan Jan Schellens, MD, Amsterdam, The Netherlands Deborah Schrag, MD, New York, NY Andrew D. Seidman, MD, New York, NY Rebecca A. Silliman, MD, PhD, Boston, MA Samuel M. Silver, MD, PhD, Ann Arbor, MI Dennis J. Slamon, MD, Los Angeles, CA Eric J. Small, MD, San Francisco, CA Malcolm A. Smith, MD, PhD, Bethesda, MD Alberto Sobrero, MD, Genoa, Italy Jeffrey Sosman, MD, Nashville, TN Walter M. Stadler, MD, Chicago, IL David Straus, MD, New York, NY Chris H. Takimoto, MD, PhD, FACP, San Antonio, TX Theodore N. Tsangaris, MD, Baltimore, MD Joel Tepper, MD, Chapel Hill, NC Thomas M. Tursz, MD, PhD, Villejuif, France Susan G. Urba, MD, Ann Arbor, MI Eric Van Cutsem, MD, PhD, Leuven, Belgium Udo Vanhoefer, MD, Essen, Germany Alan P. Venook, MD, San Francisco, CA Jan Baptist Vermorken, MD, PhD, Edegem, Belgium Jaap Verweij, MD, PhD, Rotterdam, The Netherlands Charles F. von Gunten, MD, PhD, FACP, San Diego, CA Lawrence D. Wagman, MD, Duarte, CA Barbara L. Weber, MD, Philadelphia, PA Thomas Weber, MD, New York, NY William G. Woods, MD, Atlanta, GA John Zalcberg, MD, Melbourne, Australia Pier Luigi Zinzani, MD, Bologna, Italy JOURNAL OF CLINICAL ONCOLOGY The Official Journal of the American Society of Clinical Oncology 330 John Carlyle Street, Suite 300 Alexandria, VA 22314 Telephone: (888) 273-3508 or (703) 519-1430; Fax: (703) 518-8155 jcoservice@asco.org Editorial correspondence (manuscript-related inquiries) should be addressed to Daniel G. Haller, MD, Editor-in-Chief, Journal of Clinical Oncology, 330 John Carlyle Street, Suite 300, Alexandria, VA 22314. Telephone: (703) 797-1900; Fax: (703) 684-8720. E-mail: jco@asco.org. Internet: http://www.jco.org.