期刊名称:CLINICAL AND EXPERIMENTAL IMMUNOLOGY

ISSN:0009-9104
版本:SCI-CDE
出版频率:Monthly
出版社:WILEY, 111 RIVER ST, HOBOKEN, USA, NJ, 07030-5774
  出版社网址:http://www.interscience.wiley.com/
期刊网址:http://www.interscience.wiley.com/jpages/0009-9104/
影响因子:4.33
主题范畴:IMMUNOLOGY

期刊简介(About the journal)    投稿须知(Instructions to Authors)    编辑部信息(Editorial Board)   



About the journal

Clinical and Experimental Immunology provides an international forum for the publication of original research on all aspects of clinical immunology. It is amongst the foremost journals in this field, attracting high-quality papers from all parts of the world. Its articles cover clinical studies in patients receiving immune-based therapies, in relation to autoimmunity, primary and secondary immunodeficiencies, complement disorders and allergies. Other subjects include:

immunopathogenesis of communicable and parasitic diseases;
rheumatic, renal and endocrine disorders;
immunological disorders in other organ systems;
malignancy and transplantation.
Studies using animal models and laboratory experimentation also form a prominent feature of the Journals reports, as do papers on the physiological mechanisms of immunity. In addition to research reports, the Journal publishes general review articles and commissioned Editorial Reviews which highlight a particular topic in the issue. Occasional reports from learned societies and committees are also included making Clinical and Experimental Immunology vital reading for anyone working in clinical immunology. The journal now also features a Fast track category, enabling papers of immediate interest to reach their audience as quickly as possible.

Nalinaj Fernando Memorial Award
The editors of Clinical and Experimental Immunology award a prize of ?50 for the best research article published in the Journal on the topic of genetic immunodeficiency each year. The award has been generously donated by the Fernando family and friends in memory of Nalinaj Fernando who died, aged 32, having survived into adulthood with the extremely rare genetic immunodeficiency called "Bare Lymphocyte Syndrome". The prize commemorates his courage and determination in fighting the illness. All submissions to Clinical and Experimental Immunology in the field of immunodeficiency will automatically be entered for consideration.

The prize for the best immunodeficiency paper published in 2001/2002 was awarded to Dr S.K.A. Law of Nanyang Technological University, Singapore for his manuscript entitled "Characterization of four CD18 mutants in leucocyte adhesion deficient (LAD) patients with differential capacities to support expression and function of the CD11/CD18 intergrins LFA-1, Mac-1 and p150,95" (Clin Exp Immunol 2001; 126:311-318 FREE ACCESS TO THE FULL TEXT).  The prize for 2002/2003 will be announced at the British Society for Immunologys annual Congress in December 2003.


Instructions to Authors

Authors are encouraged to submit their manuscripts electronically. Electronic submission reduces both the costs to authors (reduced photocopying, figure preparation and postage costs) and the handling time during the review process by removing postage delays. For further information, please see below or e-mail the editorial office (cei@immunology.org).

If you are unable to submit your manuscript in this way, please send four complete copies of the text, tables and figures, along with a disk containing a word-processed file of the manuscript, to:

Dr Cate Livingstone
Managing Editor, CEI
British Society for Immunology
Triangle House
Broomhill Road
London
SW18 4HX
UK

Tel: +44 (0) 20 8875 2407/2408
Fax: +44 (0) 20 8875 2422/2424
e-mail: CEI@immunology.org

Further information regarding postal submissions can be found in the Manuscripts on disk and Illustrations sections.

For BOTH electronic and postal submissions, the following forms must be completed and returned to the editorial office at the address given above: authors declaration, Copyright Assignment, Publication Charge, Colour Work Agreement (only applicable if colour is used in the manuscript).

Copyright.  Authors will be required to assign copyright in their paper to Blackwell Publishing Ltd.  Copyright assignment is a condition of publication and papers will not be passed to the publisher for production unless copyright has been assigned.  (Papers subject to government or Crown copyright are exempt from this requirement).  To assist authors the editorial office will supply an appropriate copyright assignment form. Alternatively authors may like to download a copy of the form from http://www.blackwellpublishing.com/pdf/CEI_CAF.pdf.

Manuscript preparation

It is essential that authors retain a copy of their original manuscript as the Editor cannot accept responsibility for damage or loss of papers submitted. Papers are accepted on the understanding that all of the material submitted is the property of the authors (except where due acknowledgement is given), and that no substantial part has been, or will be, published elsewhere. Once papers have been accepted for publication they become the copyright of the Journal. Papers involving human subjects should receive local Ethical approval and the informed consent of all subjects should be obtained. Experiments involving animals should be conducted in accordance with the relevant local legislation.

Long articles which would exceed six printed pages (i.e. approximately 3000 words, with three tables and three figures or the equivalent thereof) are not encouraged.

Manuscripts should be typewritten (double spacing) on one side of standard A4 - 30 ?21 cm) paper with 30 mm margins all round and, on a separate sheet, should bear the title of the paper, a short title, name and postal and e-mail address of the author, together with the name of the Institution where the work was done; all authors use initials. For indexing purposes a small number (up to 5) of keywords should be supplied.

Generally, papers should be divided into the following parts and in the order indicated:

(1) Summary: about 3% of the length of the paper but not exceeding 250 words; (2) Introduction: containing the reasons for doing the work; (3) Materials and Methods: sufficient information must be included to permit repetition of experimental work; (4) Results: these should be given concisely; the use of tables and figures to illustrate the same results will only rarely be allowed; (5) Discussion: the presentation of results should be separated from a discussion of their significance; this section should not repeat results; (6) Acknowledgements (which must include details of financial support); (7) References: references in the manuscript text should appear as numbers in square brackets, following the authors names in text if necessary. The reference list should show the references in numerical and not in alphabetical order. The full title of the paper should be given with the first and last page numbers. The journal name should be abbreviated according to the system adopted by Index Medicus. For example:

1 Shingu M, Hurd ER. Sera from patients with systemic lupus, erythematosus reactive with human endothelial cells. J Rheumatol 1981; 8:581­6.

2 Zavazava M, Halene M, Westphal E et al. Expression of MHC class I and II molecules by cadaver retinal; pigment cells: optimization of post-mortem HLA typing. Clin Exp Immunol 1991; 84: 163-6

When the quotation is from a book, the following form should be used:

3 Kearse KP, Kaplan AM, Cohen DA. Role of cell surface glycoproteins in the formation of T­Cell: APC conjugates In: Schook LB, Tew JG, eds. Antigen presenting cells: diversity, differentiation, and regulation. New York: Alan R. Liss, 1988:221­34.

4 Virella G, Goust JM, Fudenberg HH. Introduction to medical immunology, 2nd Edn. New York: Marcel Dekker, 1990

Work which has not been accepted for publication and personal communications should not appear in the reference list. Work which has been accepted for publication should be included in the reference list stating the journal in which it is to appear.

Nomenclature

CD nomenclature is to be used for all cell differentiation antigens, with or without alternative names which give information about the molecules function. Complement receptors should be named CR1 etc., followed by the correct CD terminology in parentheses: CR1 (CD35); CR2 (CD21); CR3 (CDllb, CD18); CR4 (CDllc, CD18).

Units and Abbreviations

The Journal recognizes the adoption of the Système International dUnitès (SI Units) proposed in Units, Symbols and Abbreviations (1972) published by the Royal Society of Medicine, 1 Wimpole Street, London WIM 8AE, UK.

Other abbreviations should be used only for unwieldy names and only when they occur frequently. Where such non-standard abbreviations are used, a glossary should be provided.

Electronic Submission

All you, as an author, have to do to submit your manuscript electronically is upload a single PDF file of your paper which contains the text, figures and tables (as applicable) to a secure website, following initial registration with the site.

If you already have your manuscript prepared as a single PDF, and have read and complied with the important points regarding electronic submission, then please submit your manuscript following the instructions given on the ESPERE website.

Full information regarding PDF preparation and electronic submission can be found in the following sections: Introduction

Clinical and Experimental Immunology, as a member of the ESPERE consortium, can now receive manuscripts submitted electronically via the Internet. Both authors and referees find the system easy to use and, by reducing postal delays, it is hoped that electronic submission and peer review will result in a more efficient and faster reviewing process. Manuscripts are submitted to a secure workspace that only the editorial staff have full access to; designated referees and authors can only access those manuscripts pertaining to them.

To ensure that invited referees can read the electronic files, all manuscripts must be submitted as Adobe Acrobat PDFs. Such files avoid the general compatibility problems posed by the use of different computer systems e.g. Mac versus PC.

Please note that, although the file format required for electronic submission is PDF, authors should still prepare their manuscripts in accordance with the guidelines given above.

Accepted manuscripts may NOT be submitted as PDFs because such files cannot be used for the production process. PDF Preparation

To prepare a PDF, you will need conversion software and it is recommended that you use Adobe Acrobat. This software is not expensive and institutional discounts are available. Indeed, it may be that your institution already has a licence for the software. Please note that Adobe Acrobat is not the same as Acrobat Reader (the software used to view PDFs) which is freely available via the Internet.

If you encounter any problems, or are unable to supply your manuscript as a PDF, please contact the editorial office (cei@immunology.org) for assistance.

The following instructions outline the best way to prepare your initial electronic version of your manuscript, followed by PDF conversion.

1. Production of electronic text files
The preferred system for this Journal is IBM-compatible, using Word, but any system can be handled. You should use a general font such as Times Roman/New Roman, Arial or Helvetica throughout when preparing your manuscript. You should avoid using Far Eastern/Asian fonts. When adding symbols, e.g. Greek characters, you should use the Insert, Symbol option in the word processing program. Alternatively, you may wish to write out any unusual characters/symbols out in full.

2. Production of electronic graphics
Digital versions of figures should ideally be in native format or PICT if created on a Mac, or native format or WMF if created in Windows. Files saved as PS, EPS, GIF and TIF may also be used, but please note that it may not be possible to modify these files during production. If figures are added to the text this will tend to make the final file large so it is worth keeping individual figure files as small as possible. Figure files can be reduced considerably in size by the following methods:
(i) if colour, reduce the colour depth e.g. from millions of colours to 256 or from 256 to 16 (remember to keep an archive version)
(ii) reduce the resolution e.g. from 300 dpi to 150 dpi (not applicable to line figures where you should use 600 dpi minimum)
(iii) reduce the actual size of the figure

3. Preparation of separate PDFs
Convert each file (text, figures, tables) into a separate PDF file. This is achieved by printing to Acrobat Distiller (File, Print, Select Acrobat Distiller) rather than your usual hard copy printer. It is recommended that the final size (including figures) of your PDF is below 1MB in order to keep the transfer time to a minimum. If your final file size is greater than this, please use the Compression option. To achieve this in Acrobat Distiller, select Settings, Job Options, Compression. You can reduce the resolution to 150 or even 72 dpi for screen viewing of colour or greyscale images. For line diagrams use a minimum of 600 dpi. Please ensure that the Embed all fonts box in the Properties option that appears in the print dialog box is ticked. To ensure that Far Eastern/Asian fonts are embedded, you must use Acrobat version 4 and Acrobat Distiller.

4. Preparation of a single PDF
Compile a single PDF from the multiple files. Open the Acrobat program (referred to as Acrobat Exchange) and then open the PDF containing the text of your manuscript. Using the Document option on the toolbar, select Insert pages..., chose the file containing the next section of the manuscript to be added e.g. the tables and insert the file after the last page of the text. Repeat this procedure for all additional files until your manuscript is totally contained within a single PDF. Please do NOT include the covering message within this PDF. You will be given the opportunity to write a covering message when submitting your manuscript to the ESPERE system. Save the complete file, naming the file xxxx.pdf where xxx is the surname of the first author. Do not include any unusual characters, punctuation, hyphenation, et al. or spaces in the filename.

It is advisable to print out a hard copy of the final PDF to check that everything appears as it should; symbols, figures and tables, in particular, should be carefully checked to ensure that there have not been any problems during PDF conversion.

Advice on PDF preparation can also be found on the ESPERE website in the section entitled Acrobat PDF.

Submission to ESPERE

You will need to register with the ESPERE system. To do so you will have to provide contact details, including an e-mail address, and you will be sent a password to this e-mail address. You can change the given password to something that you find more memorable. Follow the simple instructions to upload your manuscript. You can either cut and paste a covering message into the space provided or upload a separate PDF of your covering letter using the browse button provided. At Clinical and Experimental Immunology we would prefer you to use the cut and paste option. Please note that for submission to Clinical and Experimental Immunology you MUST copy and paste the abstract into the space provided.

To register with ESPERE and submit a paper, please click here:

Important Points

Please pay particular attention to the following important points when preparing your electronic submission:
1. Use a general font such as Time


Editorial Board

Managing Editor
Dr Cate Livingstone
Clinical & Experimental Immunology
British Society for Immunology
Triangle House
Broomhill Road
London
SW18 4HX
UK

Tel: +44 (0) 20 8875 2407/2408
Fax: +44 (0) 20 8875 2422/2424
e-mail: CEI@immunology.org

Editor-in-Chief

Professor A. P. Weetman, Northern General Hospital, Sheffield, UK

Associate Editors

Dr D. M. Altmann, Clinical Sciences Centre, RPMS at Hammersmith Hospital, Du Cane Road, London, W12 0NN, UK

Professor B. P. Morgan, University of Wales College of Medicine, Heath Park, Cardiff, CF4 4XN, UK

Professor D. B. G. Oliveira, St Georges Hospital School of Medicine, Cranmer Terrace, London, SW17 0RE, UK

Professor S. L. Rowland-Jones, Institute of Molecular Medicine, John Radcliff Hospital, Headley Way, Headington, Oxford, OX3 9DU, UK

Dr A. D. B. Webster, MRC Immunodef Res Group, Royal Free Hospital, Pond Street, London, NW3 2QG,UK

Professor D. C. Wraith, University of Bristol, University Walk, Bristol, BS8 1TD, UK

All manuscripts submitted to Clinical and Experimental Immunology are peer-reviewed by two independent referees and also assessed by an editor prior to publication. Referees complete a standard evaluation form, as well as providing comments for the editors and authors, ensuring that the quality of manuscripts published in the Journal is maintained to a consistently high standard.

The Journal is a member of the Committee on Publication Ethics (COPE) and authors submitting manuscripts to the journal are recommended to read the Guidelines on Good Publication Practice.

The Journal is also a member of the World Association of Medical Editors.


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