期刊名称：PHARMACEUTICAL CHEMISTRY JOURNAL
 期刊简介(About the journal)
投稿须知(Instructions to Authors)
编辑部信息(Editorial Board)
About the journal
More than 40 years in publication through 2007, the monthly Pharmaceutical Chemistry Journal is devoted to scientific and technical research on the creation of new drugs and the improvement of manufacturing technology of drugs and intermediates. International contributors cover the entire spectrum of new drug research, including methods of synthesis; results of pharmacological, toxicological, and biochemical studies; investigation of structure - activity relationships in prediction of new compounds; methods and technical facilities used; and problems associated with the development of ecologically safe and economically feasible methods of industrial production.
In addition, analytical reviews of international literature in the field report on recent developments around the world.
Pharmaceutical Chemistry Journal is a translation of the peer-reviewed Russian journal Khimiko-Farmatsevticheskii Zhurnal.
Abstracted/Indexed in:
Academic OneFile, Academic Search, AGRICOLA, Chemical Abstracts Service (CAS), Chemistry Citation Index, ChemWeb, CrossFire, CSA/Proquest, Current Abstracts, EMBASE, Gale, Google Scholar, INIS Atomindex, International Pharmaceutical Abstracts, Journal Citation Reports/Science Edition, OCLC, Science Citation Index Expanded (SciSearch), SCOPUS, Summon by Serial Solutions, TOC Premier, VINITY - Russian Academy of Science
Instructions to Authors
Manuscript Submission
Contributions should be sent to the Editorial board of the Russian language journal (not to Springer), at the following address: Pharmaceutical Chemistry Journal(Khimiko-Farmatzevticheskii Zhurnal)Krasina Street, 2Research Centre on Biomedical TechnologiesVILAR123056 MoscowRussiaPhone: + 7 495 254 1033E-mail: chem@folium.ruPlease note that the priority is given for papers, contributed in the Russian language. Instructions on the preparation of a manuscript in Russian are available at the following link: Instructions for Authors : www.chem.folium.ru/rules.htm
Scope
Instructions for Contributions in English Papers submitted to Pharmaceutical Chemistry Journal / Khimiko-Farmatsevticheskii Zhurnal should reflect new, previously unreported investigations performed at the modern scientific and technological level and advanced commercial experience in the following fields:
|
Molecular biology and biochemistry: isolation of promising pharmacological substances; elucidation of the mechanisms of drug action; establishment of the structure - activity relationships; optimization of the search for new drugs.Experiments aimed at obtaining new compounds, including those isolated from medicinal plants, and studying their pharmacological properties.Scientific and technological works aimed at the creation of new and the development of existing methods of synthesis of drugs and semi products, with a view to increasing quality of medicinal products; economy of materials, energy, and labor input; increase in the ecological safety and labor conditions by means of rational use of raw materials and wastes, development of waste-free technologies, application of new analytical and control facilities, in particular, automated systems for the control of technological processes, operating equipment, and plants.Design of new and modernization of existing equipment for chemico-pharmaceutical plants (including mechanization and automation of dangerous and laborious operations), aiming to increase their technological and economic efficiency.Description of the properties and applications of new medicinal products.Achievements in domestic and world science and technology of interest for scientists engaged in pharmaceutical chemistry and engineers of chemico-pharmaceutical plants, including reviews and brief information on the published literature; Information about scientific meetings, conferences, and exhibitions; Book reviews; Papers for discussion of scientific and technological problems; Urgent publications on important topics as “Letters to Editor�(note: publishing a “Letter to Editor�does not prohibit submitting a detailed paper on the same subject). | The papers should be submitted by authors immediately and creatively participating in the whole work. Participants contributing in separate stages can be mentioned in the text.Material must be presented in the following order:1. Papers presenting the results of experiments on the synthesis of new compounds and their characterization should contain separate chemical and biological experimental parts:a. The experimental chemical part describes the methods of synthesis and analysis of the obtained compounds and describes their physicochemical properties. In particular, this section indicates:
|
the amounts of initial reactants (in grams and moles);the sequence and conditions of operations, including isolation and purification stages (temperature, pressure, treatment time, and other parameters);data of elemental analyses and physicochemical properties (in a separate table) confirming the proposed structures. When several compounds are obtained using the same method, the procedure has to be described for one compound only;data characterizing the comparative properties of a series of compounds (in the form of a table). | b. The experimental biological part indicates:
|
the methods of investigation used for determining the biological activity (original methods should be described in detail);the types and numbers of experimental animals (these experiments should be performed with observation of all conventional rules established for work with experimental animals);the results of tests, with indication of the activity and toxicity of compounds studied in comparison to the analogous reference substances. | In the discussion and conclusion, the paper should (if possible) consider the relationship between structure and activity of the compounds studied and give a conclusion concerning both basic and applied significance of the results.2. Paper devoted to the development of drug production technology and methods of commercial synthesis, analysis, and control, should describe the following (including separate experimental part):
|
newly developed methods and technological processes;sequence and conditions of separate stages;equipment, devices, instruments, and other technical facilities;amounts of charged materials and discharged products, with error limits (for methods of analysis and control);bother technical and economic data necessary for the reproduction of the proposed methods and processes and evaluation of their efficiency. | 3. Papers presenting new medicinal products should compile:
|
data on the chemical and physical properties;molecular and structural formulas;main results of the biological tests and clinical investigations;data on the administration doses, indications and counter indications;other data corresponding to the conventional instruction for use, with indication of the registration certificate numbers and available forms of a given drug | 4. New substances (isolated or synthesized) should be given names in accordance with recommendations of the International Union of Pure and Applied Chemistry (IUPAC) and the International Union of Biochemistry (IUB). Enzymes should be named in accordance with the IUB catalog, with the corresponding enzyme number indicated in square brackets. Indicate Latin names of plants and microorganisms.5. The paper should be provided with recommendations concerning the possibility of using the results in basic research and / or practice.
Manuscript Form
The manuscript must typically not exceed 8 �10 typeset pages (1.5-spaced, font size 12), including the title page, references, tables, figures with captions, photographs, and any appendixes. The volume of review papers can be increased to 18 �20 pages.The title page should contain a concise but informative title, initials and surnames of all the authors (in Russian and English), the names of institutions (without abbreviations), and their locations (city, country).The manuscript should be neatly typed (1.5-spaced, font size 12) on one side only on A4 (21 x 30 cm or in) white paper with 3-cm left-hand margin. Neither written nor glued insets are allowed. The article can be submitted on disk written in Microsoft Word text editor, stored in rich text format (rtf), but a printed copy is obligatory.All pages in the manuscript are to be numbered in a single sequence beginning with the title, running through text, references, tables, and list of figure captions. Original figures have to be submitted with the manuscript.Manuscript FormThe manuscript is submitted in duplicate (original and copy) undersigned by all the authors. The accompanying material for the Editor should contain the full address (with zip code), phone number (work and /or home), and e-mail of the author to whom all correspondence from the Editor should be sent.Formulas, Terms, Units of MeasureUse commonly accepted physical, chemical, technical, and mathematical terms, units of measure, and notations. Abbreviations of the units should follow recommendations of the International Union of Pure and Applied Chemistry (IUPAC).Equations should be numbered with Arabic numerals in parentheses on the right.Chemical compounds should be given full names (according to IUPAC Nomenclature) and denoted by Roman numerals in parentheses (the same Roman numerals without parentheses are used with incomplete names).Equipment, instruments, and other technical facilities, as well as special materials used in the work should be given with indication of the model type, manufacturer, and country (e.g., JEM 100 electron microscope (JEOL, Japan)). The original (named) reactions and methods should be given in original transcription (e.g., Lowry method).Typical examples of using abbreviations for methods and data presentation are as follows:Compound I: yield, 2.55 g (84.9 %); b.p., 52°C/10 Torr; b.p., 78°C (reported: 77°C [5]); , +8.2° (c, 2.01; EtOH); , 0.8703; , 1.5814; Rf, 0.44; MR D, 45.07 (calcd., 45.12).Use the following abbreviations of units frequently encountered in the text:second (unit of time) secliter (unit of volume) litermilliliter mlmicroliter μlmicron μmgram-molecule moleMelting and boiling points of substances in the text and table headings are denoted as m.p. and b.p., respectively.Orientations of substituents in chemical compounds are written in italic: ortho- (o-), metha- (m-), para- (p-), trans-, cis-, gauche-, sec-, tert-, E-, Z-, R-, S-, L-, D-, etc.Avoid excessive use of abbreviations overloading the text. The first use of abbreviations in the text should be clearly explained.The following common abbreviations can be used without such explanations: UV (ultraviolet), IR (infrared), NMR (nuclear magnetic resonance), TLC (thin layer chromatography), GC (gas chromatography); DTA (differential thermal analysis), HPLC (high-performance liquid chromatography).NotationHandwritten formulas and symbols should be neatly written in black ink. All formulas and symbols whose identity may not be obvious must be identified in the margin the first time they appear, including:(i) capital letters (two bottom bars) and low-case letters (two top bars), especially for letters such as “c� “o� “p� “s� “x� “z�(ii) italics (wave) and boldface (single bottom bar); give all variables in italic and vectors in bold;(iv) capital wo bottom bars), low-case two top bars), and zero 0; and low-case and Latin numeral (v) superscripts (penciled underneath the superscript) and subscripts (penciled over the subscript); avoid using two- and multilevel subscripts and superscripts.In structural formulas, differentiate between valence (chemical) bonds (single, double, triple) and the hyphen, n- or m-dash, and equality sign (in case of ambiguity, indicate on the margin the first time they appear). Check exact positions of the symbols of valence bonds (against the corresponding atoms or groups), ion charges, radical signs, etc. Note that indexes on the right of a radical sign R indicate the number of identical radicals (subscript) and different variants (superscript).FiguresFigures are to be submitted in duplicate (each in a separate envelope). The figures should be neatly drawn in India ink on A4 sheets of white paper or tracing paper. The figure axes should be parallel to the paper edges. The letter notation should be generally the same as that in the text of the manuscript. The lettering should be also written in India ink.The coordinate axes should be provided with names or symbols of the corresponding variables ad the units of measure (conventionally abbreviated) separated by comma. For example, in presenting spectroscopic data for the UV and visible spectral range, the abscissa indicates wavelength (λ, nm) and the ordinate gives molar extinction (lg ε); for the IR and Raman spectra, the abscissa indicates wave number (1.20 ) and the ordinate shows the percentage transmission (e.g., T, %), absorption (e.g., A, %), or intensity (I, rel. units).Photographs should be submitted in exceptional cases (provide schematic line diagrams whenever possible instead). Photographs should be clear, of highcontrast, with well-resolved details, and made on white glossy photographic paper.All figures should be numbered by Arabic numerals in the order in which they are referred to in the text. The explanatory legends are provided with explanatory legends (list of captions) on a separate page. Captions describe the figures and explain lettering and other notation. All figures are obligatory referred to in the text (e.g., Fig. 1) and indicated on the margin of the manuscript the first time they appear.Each figure should be identified on the back, by its number, the name of the first author, and the journal; in cases where the orientation is ambiguous, indicate the top of the figure.TablesTables should be provided with captions and numbered (e.g., Table 1) in the order they are referred to in the text. Avoid tables constructed as several-level headings with a single line of data (such data can be presented in the text). Columns should have simple headings (capitalized) with units (abbreviated). Common elements of column headings should be separated into common heading lines. Avoid including figures and structural formulas in table columns.
References and Footnotes
References are numbered in the order they appear in the text (in square brackets) and listed at the end of the paper. Footnotes are also numbered consecutively in order of first appearance (to be placed on the same page) and printed double-spaced on a separate sheet at the end of the text. For the proper form, see recent issues of this journal.In the list of references, author names are typed in the following order: initials with dots and surname, all spaced by one interval. All authors of the source cited are given unless their number is more than four; in the latter case, the third author’s name is followed by et al..For journals, the paper title is not given; the list of authors is followed by (separated by commas) the journal title (abbreviated according to CASSI, single-word titles not abbreviated), volume number or issue number preceded by No. (if both volume and issue numbers are indicated, the latter is given in parentheses without interval), first page or page interval and year in parentheses.Examples:1. T. I. Mukhanova, L. M. Alekseeva, E. F. Kuleshova et al., Khim.-Farm. Zh., 27(2), 60 â€?65 (1993).2. V. M. Lyubchanskaya and V. G. Granik, Khim. Geterotsikl. Soedin., No. 1, 40 â€?45 (1993).3. R. F. Abdulla and R. S. Brinkmayer, Tetrahedron, 35, 1675 â€?1677 (1979).For books, the list of authors is followed by (separated by commas) book title, publisher, city and year in parentheses, volume number (preceded by Vol., for many-volume editions), issue (No.) or chapter (Ch.) number, and page (p.) or page interval (pp.). Total number of pages is not indicated. For books representing collections of papers, the list of authors of a paper is followed by “in:â€?and the book title is followed by the list of editors and (ed.) or (eds.). Examples:1. T. R. Ponomareva and O. M. Dronova, Antibacterial Cultures [in Russian], Meditsina, Moscow (1984), pp. 23 27.2. Reviews of Plasma Physics, M. A. Leontovich (ed.), Consultants Bureau, New York (1975), Vol. 6, pp. 8488.3. G. W. Andersen, in: Peptides. Chemistry and Biochemistry, B. Weinstein and S. Lande (eds.), Marcel Dekker, New York (1970), pp. 225266.For some other editions such as abstracts and proceedings of conferences, dissertations, and patents (accompanied with reference to Chem. Abstr., Ref. Zh. Khim., or Byull. Izobret.), see examples:1. G. A. Mokrushina, S. G. Alekseev, V. N. Charushin, et al., Proceedings of the 5th All-Union Conf. on the Chemistry of Nitrogen-Containing Heterocycles, Chernogolovka (1991), pp. 15 23.2. Yu. A. Azev, V. N. Charushin, and O. N. Chupakhin, Abstracts of Papers. The 10th Interdisciplinary World Congress on Antimicrobial and Anticancer Drugs, Geneva (1992), Abstr. 31.2. L. I. shakov, Authorâs Abstract of Cand. Sci., (Biol.) Dissertation, Moscow (1991).3. Jpn. Patent No. 69939; Chem. Abstr., 117, 137670x (1992).References to unpublished papers and dissertations are not allowed. Authors are responsible for the correctness of references.Dear AuthorsManuscripts not obeying the above rules may be returned for revision, correction, or abridging. Please return the revised manuscript promptly together with the initial variant.
Copyright Information
Submission of a manuscript implies that the work described has not been published before (except in the form of an abstract or as part of a published lecture, review, or thesis); that it is not under consideration for publication elsewhere, that its publication has been approved by all co-authors, if any, as well as (tacitly or explicitly) by the responsible authorities at the institution where the work is carried out.
Editorial Board
Editor-in-Chief:
R.G. Glushkov
Secretary:
K.S. Shanazarov
Editorial Board:
A.P. Arzamastsev; E.V. Degterev; V.I. Gunar; I.S. Gushchin; T. A. Guskova; S.D. Juzhakov; P.M. Kochergin; V.V. Poroikov; M.N. Preobrazhenskaya; A.N. Saprin; S.B. Seredenin; L.N. Sernov; A.M. Yurkevich; Yu.G. Zelinskii
Authors and referees, please contact the Scientific Editor-in-Chief, Dr R.G. Glushkov:
e-mail: chem@folium.ru
|
