期刊名称：PROTEIN ENGINEERING DESIGN & SELECTION
 期刊简介(About the journal)
投稿须知(Instructions to Authors)
编辑部信息(Editorial Board)
About the journal
A Community-Based Journal for Protein Scientists
In January 2004, the journal Protein Engineering was relaunched as Protein Engineering, Design and Selection, or PEDS. PEDS publishes research papers and review articles relevant to the engineering, design and selection of proteins for use in biotechnology and therapy, and
Instructions to Authors
Follow the manuscript preparation instructions carefully. Failure to follow these instructions may lead to delay in the publication of your manuscript. Use version 4.0 or higher of Netscape or Internet Explorer. If you have trouble finding manuscripts or have other problems with your account do not create another account. Instead, e-mail ScholarOne) or telephone +1 434 817 2040 extension 167.
Go to the Author Centre on the Manuscript submission Web site and follow the on-screen instructions. Move between screens by selecting the Save and Continue or Previous buttons. Information you have entered will not be saved if you use your browser's Back or Forward buttons . You can stop or suspend submission at any stage by selecting Return
In the File Upload Centre:
Select Browse to locate your files. Select the file type from the pull-down menu. An initial submission of the main manuscript should be uploaded as a single .pdf file containing all components of the manuscript including text, tables and figures. (Supplementary Material files should be uploaded as separate files formatted as they will appear if accepted for publication.)
Select whether files should be considered for review (default is Yes). If you select No, editorial staff will still be able to view the file and make it available to an editor or reviewer if necessary.
Select Upload to submit your file.
When an upload is complete, you will see a confirmation window asking for a description of the file. Refer to your Main Document as Manuscript Text or Main Document. Refer to figures by number, e.g. Figure 1 or Fig. 1. For other supporting files indicate clearly what the file is as well as its format (MS Excel, MS Word, etc.).
The on-screen version of your manuscript, which is the version accessed by the editor and reviewers, can be viewed and proofed after it has been successfully uploaded.
You can remove files and repeat the upload process at the File Upload screen, accessed by selecting Previous.
When you are satisfied with the uploaded manuscript select Submit. It is not until this button is pushed that the manuscript and all of the associated information (i.e., contributing authors, institutions, etc.) is linked together and the manuscript is given a manuscript number. Once the manuscript is submitted it is not possible to undo the submission.
After the manuscript has been submitted you will receive an e-mail confirmation stating that your manuscript was successfully submitted. This e-mail will also give the assigned manuscript number, which is used in all correspondence. If you do not receive this e-mail, your manuscript will not have been successfully submitted to the journal and the paper cannot progress to peer review. If this is the case your manuscript will still be sitting in the 'Unsubmitted Manuscripts' section of your 'Author Center' awaiting your attention.
If you return to your Author Centre you will notice that your newly submitted manuscript can be found in the Submitted Manuscripts area. Among the information listed there, the Processing Status section provides information on the status of your manuscript as it moves through the review process.
Submitting a Revised Manuscript
Log on to the Manuscript submission site as before. Access your manuscript by selecting its title in the Manuscripts to be Revised section of the Author Centre.
Upload your revised manuscript using the File Manager screen. It is essential that you upload your revised manuscript as a .doc .rtf or .ps file. PDF files cannot be used for production.
Paste your response to reviewers' and editor's comments in the text areas at the bottom of the View comments/respond screen
Important
If your paper goes on to be accepted, your images will be required as high-resolution .tif files (1200 d.p.i. for line drawings and 350 d.p.i. for color and half-tone artwork) or high-quality printouts on glossy paper. There is useful information on preparing your figures for publication available. Please note that publication of your manuscript will not proceed until figures suitable for reproduction are received.
Full instructions on how to prepare accepted manuscripts for submission are available.
Getting Help
If you experience any problems during the online submission process please use
Editorial Board
EditorsSENIOR EDITORSAlan Fersht
UK
Greg Winter
UK
Valerie Daggett
US
REVIEWS EDITORDan
Tawfik, Israel
EDITORIAL BOARD
Tom Alber
US
X-ray crystallography; computational design; enzyme structure; protein kinases; protein-protein interactions; allosteric regulationFrances Arnold
US
Directed evolution; cytochrome P450; protein design; in vitro selection; enzyme engineeringP Balaram
India
Protein design; de novo peptide design; protein folding; analysis of motifs; disulfide engineeringLars Baltzer
Sweden
De novo protein design; (protein design); peptide; bioorganic; catalysis; molecular recognition; reactivityHagan Bayley
UK
Biosensors; biomolecular materials [fibers, elastomers, adhesives etc.];chemical modification of proteins; membrane proteins; photochemistry; single molecule biologyHugues Bedouelle
France
Recombinant antibody; aminoacyl-tRNA; synthetase; biosensor; infectious agent; phage display; protein stability; therapeutic proteinAlbert Berghuis
Canada
Structural Biology; structural bioinformatics; computational chemistry; enzyme mechanism; enzyme evolutionAlan Berry
UK
Directed evolution; mechanistic enzymology; aldolases; enzyme engineeringCarl Borrebaeck
Sweden
Immunotherapy; antibody engineering; target discovery; cancer; lymphomas; B cell developmen; microarrays; proteom analysis; allergyAndrew Bradbury
US
Phage display; selection systems; antibodies; fluorescent proteins; GFP; cre/lox recombinationDennis Burton
US
Antibodies; antibody engineering; virus glycoproteins; HIV; prion proteinsPaul Carter
US
Antibodies; in vitro evolution; therapeutic proteinsAshutosh Chilkoti
US
Protein based polymers; stimuli responsive polypeptides; protein-polymer conjugatesFabrizio Chiti
Italy
Protein misfolding; protein aggregation; protein folding; amyloid fibrils; mechanisms of amyloid formation; protein deposition diseases; amyloid diseasesBrian Clark
Denmark
Protein synthesis; proteomics; protein modification; ageingJane Clarke
UK
Protein folding; protein stability; protein dynamics; force spectroscopy; AFM; protein elasticity; single molecule studiesMarius Clore
US
NMR spectroscopy; structural biology; protein-protein interactions; protein-nucleic acid interactions; transcriptionfactors; signal transduction; computational chemistry; structure determination methods; structure predictionFred Cohen
US
Protein misfolding; prion diseases; heteropolymer design; protein modelingMirek Cygler
Canada
Protein structure; enzymatic mechanism; glycosaminoglycan processing enzymes; proteases and esterases; structural genomicsAlan Davidson
Canada
Protein folding; mutagenesis; SH3 domains; folding and sequence conservationMichael Deem
US
Statistical mechanics; protein evolution; original antigenic sinWilliam DeGrado
US
Protein design; bioinorganic chemistry; protein foldingBauke Dijkstra
Netherlands
Protein structure; enzyme mechanisms; protein engineering; crystallography; biophysical techniquesChristopher Dobson
UK
; William Eaton
US
Protein dynamics, folding and self-assembly; sickle cell diseaseDavid Eisenberg
US
Amyloid; domain swapping; prion structure; protein interations; functional networksEdward Eisenstein
US
Jacques Fastrez
Belgium
Directed evolution; selection for catalytic activity; phage display; proteases; lactamases and peptidasesAngelo Fontana
Italy
Protein folding; proteolysis; biospectroscopy; protein chemistry ; mass spectrometryAdrian Goldman
Finland
Protein structure; x-ray crystallography; enzyme modification; protein evolutionRichard Goldstein
UK
Protein evolution; protein bioinformaticsAndrew Griffiths
UK
Directed evolution; selection; phage display; antibody selection; enzyme evolutionBernd Gutte
Switzerland
De novo design of functional peptides; protein folding; retro-proteins; phage display of peptide librariesMichael Hecht
US
Protein design; combinatorial methods; library design; mutagenesis; binary patterning; protein expressionDon Hilvert
Switzerland
Phil Holliger
UK
Directed evolution; repertoire selection; polymerases; replication; nucleotide chemistryHennie Hoogenboom
Netherlands
Antibody engineering; protein expression; display methods; molecular evolution; cancer immunotherapyNick Hoogenraad
Australia
Molecular chaperones; protein folding; stress response; protein targeting; mitochondrial biogenesisAmnon Horovitz
Israel
Chaperonins; allostery; mutant cycles; protein foldingArthur Horwich
US
Molecular chaperones; chaperonins; GroEL; folding in vivo; amyloids; TTRPeter Hudson
Australia
Protein structure and design; directed molecular evolution; display and selection technologies; protein arrays and biosensorsTaiji Imoto
Japan
Stabilization; folding; reaction mechanisms; chemical modification; antigenicityDick Janssen
Netherlands
hydrolases; enzyme kinetics; biocatalysis; dehalogenasesLaurent Jespers
UK
Phage display; antibody engineering; molecular evolution; domain antibodyMartin Karplus
US
Molecular dynamics simulations of biomolecules ; QM/MM calculations of enzyme systems; free energy simulations of biomolecules; molecular motors; solution statistical mechanicsJeff Kelly
US
Thomas Kiefhaber
Switzerland
Protein folding; protein stability; reaction kinetics; protein dynamicsAndreas Kungl
Austria
Protein engineering; fluorescence; circular dichroism; microcalorimetry; proteomics; molecular dynamics; chemokinesRobin Leatherbarrow
UK
Peptide chemistry; peptide synthesis; protease; protease inhibitor; protein; NMR; enzyme kinetics; enzyme inhibition; molecular interactionsBengt Mannervik
Sweden
Glutathione; combinatorial protein chemistry; directed evolution; phage display; protein redesignSusan Marqusee
US
James Marks
US
Andreas Matouschek
US
Protein folding and unfolding; protein degradation; ATP-dependent proteases; protein translocation across membranes; mechanism of protein machinesBrian Matthews
US
Protein crystallography; protein stability; protein design.Robert Matthews
US
Protein folding; protein stability; folding and assembly of multi-subunit proteinsStephen Mayo
US
Protein design; protein stability; combinatorial optimization; molecular modeling; force fieldsLiz Meiering
Canada
Protein folding; protein stability; protein misfolding and aggregationAndr?Menez
France
Protein design (antibodies; mini-proteins; enzymes); structural analyses (X-ray, NMR and CD); Mutational analysesVadim Mesyanzhinov
Russia
Protein design; foldon; enzybiotics; virus; bacteriophageAndrew Miranker
US
Protein folding; spectroscopy; amyloid; protein-protein interactions; complex assemblyKosuke Morikawa
Japan
Protein crystallography; DNA binding protein; ligand receptor interactionHaruki Nakamura
Japan
Structural bioinformatics; protein and proteome databases; structural proteomics; molecular simulation; protein foldingDario Neri
Switzerland
Therapeutic antibodies; protein libraries and selection methodologies; chelate effect and high-affinity binding; protein-based in vivo targeting, with special emphasis on angiogenesis-related diseasesFeng Ni
Canada
Polypeptide design; signaling protein interactions; binding allostery; instrinsically-unstructured proteins (IUPs); NMR; blood coagulation and antithromboticsRobin Offord
Switzerland
Chemically synthesized proteins; semisynthetic proteins and peptides; chemokines; HIV receptor antagonistsMikael Oliveberg
Sweden
David Ollis
Australia
X-ray crystallography; protein structure; function and engineering; directed evolution; enzyme mechanismJane Osbourn
UK
Antibody engineering; phage display; ribosome display; selection technologyHartmut Oschkinat
Germany
Daniel Otzen
Denmark
Protein folding kinetics; protein stability; membrane protein biophysics; protein fibrillation; surfactantsEvamaria Petersen
Denmark
Protein engineering; molecular directed evolution; lipase; lipid binding proteinsAndreas Plueckthun
Switzerland
Directed evolution; display and selection technologies; ligand binding; protein stability; antibody engineering; protein designFlemming Poulsen
Denmark
Protein struture; protein folding; protein dynamics protein stability and NMR spectroscopySheena Radford
UK
Folding; misfolding; amyloid; single molecules; AFMDaniel Raleigh
US
Amyloid formation and protein aggregation; protein design; protein stability and thermodynamics; NMRAnthony Rees
Sweden
Antibody modeling; antibody mimetics; artificial receptorsLynne Regan
US
Protein design; folding; stability; helical proteins; protein-metal interactions; protein-protein interaction; protein-RNA interactionsHeinrich Roder
USA
Protein folding; kinetics; folding intermediates; rapid mixing; NMR; hydrogen exchangePeter Roepstorff
Denmark
Mass spectrometry; proteomics; post translational modifications; protein interactionSteven Russell
US
Virotherapy; gene therapy; virus display; targeting; membrane fusionAndrej Sali
US
Protein structure analysis and modeling; protein assembly analysis and modelingMark Sansom
UK
Membrane proteins; ion channels; molecular dynamics; homology modellingHarold Scheraga
US
Protein folding; physical chemistry; statistical mechanics; global optimizationGideon Schreiber
Israel
Protein-protein interaction; binding kinetics; proteomics; protein design; interferon; cooperativityKlaus Schulten
US
Computational biology; membrane proteins; mechanical proteins; photosynthetic apparatus; nanosystem bioengineering; Luis Serrano
Germany
Folding; Design; Biocomputing; Amyloid; Structure analysisP C Shaw
Hong Kong
Molecular biology & protein engineering; protein-protein interaction; ribsome inactivating protein; N-glycosidase; DNA methylaseArne Skerra
Germany
Rational design; combinatorial selection; antibody engineering; binding proteins; protein crystallographyDieter Soll
US
Aminoacyl-tRNA synthetases; RNA modification enzymes; RNA; protein interactionsTobin Sosnick
US
Protein folding; RNA folding; kinetics; hydrogen exchange; small-angle scatteringPatrick Stayton
US
Biohybrid materials; smart protein conjugates; biomineralizationMichael Sternberg
UK
Bioinformatics; protein modellingRobert Stroud
US
Protein crystallography especially applied to membrane channels and receptors and to drug design aimed at therapeutically important targetsJoel Sussman
Israel
Protein crystallography; bioinformatics; neurobiology; intrinsically unfolded proteins; structural proteomics; halophilic/halotolerant proteins; acetylcholinesterase/butyrylcholinesteraseDan Tawfik
Israel
Enzyme evolution; directed evolution; enzyme mechanisms; protein conformation; antibodiesDavid Thirumalai
US
Computational and theoretical biophysics; protein folding; protein aggregation; chaperone-mediated folding; single molecule studiesHans Thøgersen
Denmark
Antibody mimics; protein tinkering; protein-drug design; refolding; large-scale protein processingJanet Thornton
UK
Computational biology; bioinformatics; structural biology; genomicsBruce Tidor
US
Computational biology; protein and ligand design; electrostatic interactions; molecular dynamics; protein-DNA interactions; systems biologyIan Tomlinson
UK
Antibody engineering; antibody sequences and structures; antibody based therapeutics; protein repertoires; in vitro evolution of proteinsJayant Udgaonkar
India
Mathias Uhlen
Sweden
Proteomics; combinatorial selection; affinity purification; expression profilingSally Ward
USA
Rik Wierenga
Finland
Protein crystallography; protein engineering; TIM; CoA; enzymologyTony Wilkinson
UK
Protein structure; enzyme mechanisms; protein engineering; crystallography; expression systemsRoger Williams
UK
Protein structure; signal transduction; protein/lipid interactions; phosphoinositide signallingStephen Withers
Canada
Enzyme mechanisms; glycosyl transfer; glycosidase; carbohydratesKambo Wong
Hong Kong
NMR; protein crystallography; protein stability; protein engineeringDek Woolfson
UK
Structural studies of peptides and proteins; rational protein design; combinatorial design and selection; nanobiotechnologyMark Zoller
US
Molecular biology and protein engineering; phage display; protein kinases; GPCRs and ion channels involved in taste and smell
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