期刊名称：JOURNAL OF BIOTECHNOLOGY
 期刊简介(About the journal)
投稿须知(Instructions to Authors)
编辑部信息(Editorial Board)
About the journal
Description
The Journal provides a medium for the rapid publication of both full-length articles and short communications on all aspects of biotechnology. The Journal will accept papers ranging from genetic or molecular biological positions to those covering biochemical, chemical or bioprocess engineering aspects as well as computer application of new software concepts, provided that in each case the material is directly relevant to biotechnological systems. Papers presenting information of a multidisciplinary nature that would not be suitable for publication in a journal devoted to a single discipline, are particularly welcome. The following is an outline of the areas covered in the Journal:
Nucleic Acids/Molecular Biology: Novel contributions in the general area of Nucleic Acids/Molecular Biology will be considered. This includes studies for the physical and functional characterization of genomes, studies on the expression of genomic information in cellular and cell-free systems, the development and application of technologies for the detection of single molecules and molecular interactions (molecular recognition), the development and application of strategies towards the identification of biotechnologically interesting new compounds via chemical synthesis (combinatorial strategies in particular), molecular design and evolution, as well as molecular bioinformatics. The development of automated systems for the above mentioned fields may be of particular interest.
Physiology/Biochemistry: This section covers biochemical and physiological studies of metabolism and enzymes as relevant to the product formation including intermediary metabolism of micro-organisms, tissue culture cells and cell-free systems; bioregulatory investigations at the molecular level including transciption/translation control and growth/product-synthesis relationships; design and engineering of products by molecular strategies with emphasis on protein/enzyme engineering and modification; quality improvement of non-protein products; engineering of cellular modification and transport systems such as post-translational protein modifications as well as protein and metabolite secretion; novel (molecular) strategies of screening for new or modified products (e.g. pharmaceuticals, bioactive compounds, enzymes) including application with product development based on enforced evolution and combinatorial strategies.
Biochemical Engineering/Bioprocess Engineering: This section includes studies on transport phenomena, reaction kinetics, design of reactors downstream operations and software applications as well as research on cellular biology and physiology in biochemical processes employing enzymes, microorganisms, mammalian cells, plant cells and tissue. Of special interest is the rational manipulation of reactions through metabolic engineering techniques, the design of specific biocatalysts, or specific reactor operations that lead to biomaterials with unique properties. The use of a quantitative framework for the description of the processes to enhance the understanding of the experimental data is encouraged.
Instructions to Authors
Journal of Biotechnology provides a medium for the rapid publication of both full-length articles and short communications on all aspects of biotechnology. The Journal will accept papers ranging from genetic or molecular biological aspects to those covering biochemical, chemical or bioprocess engineering aspects, provided that in each case the material is directly relevant to biotechnological systems. Papers presenting information of a multi-disciplinary nature, that would not be suitable for publication in a journal devoted to a single discipline, are particularly welcome. The following areas are covered by the Journal: Nucleic Acids / Molecular Biology; Physiology / Biochemistry; Biochemical Engineering / Bioprocess Engineering.
Submission of manuscripts
Submission of a paper to the Journal of Biotechnology implies: (1) that it is not being submitted for publication elsewhere; (2) the transfer of the copyright from the author to the Publisher. One original plus two copies of the paper and the figures (copies of photographs must be original prints) should be submitted to the Chief Editor:
A. Pühler, Faculty for Biology, University of Bielefeld, Universitätsstrasse 25, D-33615, Bielefeld, Germany.
Articles from Asia may be submitted to the Japan receiving center:
Prof. T. Imanaka, Kyoto University, Graduate School of Engineering, Department of Synthetic Chemistry and Biological Chemistry, Katsura, Kyoto, 606-8501, Japan. Tel: +81 75 383 2777, Fax: +81 75 383 2778, E-mail: imanaka@sbcem.kyoto-u.ac.jp.
Authors in Asia please note that upon request, Elsevier Science Japan will provide authors with a list of people who can check and improve the English of their paper (before submission). Please contact our Tokyo office: Elsevier Science Japan, 9-15 Higashi-Azabu 1-chome, Minato-ku, Tokyo 106-0044; Tel. (03)-5561-5033; Fax (03)-5561-5047. Authors should further note that final acceptance resides with the Editor-in-Chief.
Types of papers
(1) Full-length papers, generally not exceeding 20 typewritten pages. Full-length papers should:
(a) be divided into sections (Abstract, Introduction, Materials and methods, Results, Discussion);
(b) contain an Abstract, not exceeding 200 words, at the beginning of the paper, followed by 3-6 keywords;
(c) not exceed 12-15 printed pages (approximately 20 typewritten pages) including the space required for figures. Longer papers will be considered, but may be subject to delayed publication.
(2) Short Communications, not exceeding 1500 words or equivalent space including figures and tables. These must be brief definitive reports and not preliminary findings. Short communications may not be devided into Materials and Methods, Results and Discussion, instead, Materials and Methods may be described in the text or, if apropriate, in figure legends or table footnotes.
(3) Reviews will be published following invitation from Review Editor or by the suggestion of authors.
(4) Special Issues on highlighted aspects of biotechnology are also published. Special Issues may contain selected contributions from international meetings, or a collection of papers on a specific topic, and may be composed of review articles, research papers, and short notes. Guest Editors responsible for the organisation of Special Issues will be invited by the Editors of the Journal, but may also be suggested by scientists who are willing to organize a special issue on a topic that deserves publication.
(5) Letters to the Editor and announcements of meetings and courses will be included at the discretion of the Editors and the Publisher.
(6) Supplements will be published at the discretion of the Publisher in consultation with the Editor-in-Chief. Please contact the Publisher direct for further information: Paul W. Taylor, Elsevier Science, Molenwerf 1, 1014 AG Amsterdam, The Netherlands.
Manuscripts
The manuscript should be typed with double spacing and wide margins, on one side of the paper only, and should be accompanied by a separate title page giving the authors' names and affiliations, as well as an address for correspondence including fax number and e-mail address (if available). If it is a resubmission this has to be indicated and the former J. Biotechnol. MS No. has to be given. All pages have to be numbered consecutively, including the abstract, figure legends, and tables. Place the last two items after the References section. Copies of in-press and submitted manuscripts that are important for judgement of the present manuscript should be enclosed in duplicate to facilitate reviewing.
For the title, avoid numbered series titles.
In the Abstract, avoid abbreviations and references. The Abstract should be followed by up to six Keywords.
The Material and Methods section should include sufficient technical information to allow the experiments to be repeated. When experimental conditions are critical, give enough information to enable another investigator to repeat the procedure. For commonly used methods a simple reference is sufficient. If several alternative methods are described in the paper cited, please identify the method briefly in addition to the reference. Describe new methods completely.
Present the Results as concise as possible in either table(s) or figure(s). Avoid extensive use of graphs to present data that might be more concisely presented in the text or tables. The Results and Discussion sections may be combined.
References should be assembled on a separate sheet. In the text they should be referred to by name and year (Harvard System). More than one paper from the same author in the same year must be identified by the letters a, b, c, etc., placed after the year of publication. In the text, when referring to a work by more than two authors, the name of the first author should be given followed by et al. and year in brackets. Literature references must consist of names and initials of all authors, year, title of paper referred to, abbreviated title of periodical, volume number and first and last page numbers of the paper. Periodicals, books and multi-author books should follow the examples below:
Ponti, C., Sonnleitner, B. and Fiechter, A. (1995) Aerobic thermophilic treatment of sewage sludge at pilot plant scale. 1. Operating conditions. J. Biotechnol. 38, 173-182.
Walter, H., Brooks, D.E. and Fisher, D. (1985) Partitioning in aqueous two-phase systems. Academic Press, Inc., Orlando, FL.
Hamer, G. ( 1989) Fundamental aspects of aerobic thermophilic digestion. In: Bruce, A.M., Colin, F. and Newman, P.J. (Eds.), Treatment of Sewage Sludge: Thermophilic Aerobic Digestion and Processing Requirements for Landfilling. Elsevier Applied Science, London, pp. 2-19.
Abbreviations of journal titles should conform to those adopted by List of Serial Title Word Abbreviations, International Serials Data System, 20 rue Bachaumont, 75002 Paris, France. ISBN 2- 904938-02-8.
Tables should be typed double-spaced on separate sheets, numbered consecutively with Arabic numerals, and only contain horizontal lines. A short descriptive title should appear above each table, with possible legend and footnotes (identified with a, b, c, etc.) below.
Figures should be line drawings in black ink or very sharp, well-contrasting prints on glossy paper suitable for immediate reproduction. Half-tone figures should be black-and-white, very sharp, well contrasting and on glossy paper. Figures should be completely labeled, the size of the lettering being appropriate to that of the drawing, taking into account the necessary reduction in size. All legends should be typed double-spaced on separate sheets. If figures are not to be reduced their format should not exceed 16.0 x 20.2 cm. Colour reproduction is possible. Authors wishing to publish colour figures will be expected to pay for their production costs. For more information contact the Editorial Office. Figures and photographs should be clearly marked on the reverse side with the number, author's name, and orientation (top), using a soft pencil. Use negative powers for the dimension. Figure legends have to be submitted on separate sheets.
Equations have to be numbered consecutively.
Nomenclature. A list of symbols and abbreviations (e.g., of enzymes) should be provided. 'Fermentation' and 'fermenter' have become very ambiguous expressions and, therefore, should be avoided in this Journal. Preferably use other expressions such as cultivation or bioreactor, respectively. Units and Dimensions should be expressed according to IUPAC nomenclature, e.g.
Time, s, min, h, d, a; Mass, ng,  g, mg, g, kg, t;
Length, nm, m, mm, cm, m, km; Volume, l, ml, l; Dalton, Da, for molecular mass.
Molecular weight has no dimension.
Negative powers should be used instead of fractions, e.g., g l-1 h-1, nmol ml-1, etc.
Dimensions should not be mixed with specifications, e.g., protein per biomass (g g-1) instead of g protein/g biomass.
Scientific and Engineering Symbols. Growth kinetics and cultivation: As recommended by the International Commission at the 2nd Int. Symposium on Cont. Cultivation of Microorganisms, Prague 1962 (Proceedings published by Academic Press, New York, p. 379, 1962). Other symbols: as per 'Perry's Chemical Engineering Handbook'.
Instructions regarding GenBank/DNA Sequence Linking:
DNA sequences and GenBank Accesion numbers: Many Elsevier journals cite "gene accession numbers" in their running text and footnotes. Gene accession numbers refer to genes or DNA sequences about which further information can be found in the database at the National Center for Biotechnical Information (NCBI) at the National Library of Medicine. Elsevier authors wishing to enable other scientists to use the accession numbers cited in their papers via links to these sources, should type this information in the following manner:
For each and every accession number cited in an article, authors should type the accession number in bold, underlined text. Letters in the accession number should always be capitalised. (See Example 1 below). This combination of letters and format will enable Elsevier's typesetters to recognize the relevant texts as accession numbers and add the required link to GenBank's sequences.
Example 1: "GenBank accession nos. AI631510, AI631511, AI632198, and BF223228), a B-cell tumor from a chronic lymphatic leukemia (GenBank accession no. BE675048), and a T-cell lymphoma (GenBank accession no. AA361117)".
Authors are encouraged to check accession numbers used very carefully. An error in a letter or number can result in a dead link.
In the final version of the printed article, the accession number text will not appear bold or underlined (see Example 2 below).
Example 2: "GenBank accession nos. AI631510, AI631511, AI632198, and BF223228, a B-cell tumor from a chronic lymphatic leukemia (GenBank accession no. BE675048), and a T-cell lymphoma (GenBank accession no. AA361117)".
In the final version of the electronic copy, the accession number text will be linked to the appropriate source in the NCBI databases enabling readers to go directly to that source from the article.
Electronic manuscripts
Electronic manuscripts have the advantage that there is no need for the rekeying of text, thereby avoiding the possibility of introducing errors and resulting in reliable and fast delivery of proofs. For the initial submission of manuscripts for consideration, hardcopies are sufficient. For the processing of accepted papers, electronic versions are preferred. After final acceptance, your disk plus two, final and exactly matching printed versions should be submitted together. Double density (DD) or high density (HD) diskettes (3.5 or 5.25 inch) are acceptable. It is important that the file saved is in the native format of the wordprocessor program used. Label the disk with the name of the computer and wordprocessing package used, your name, and the name of the file on the disk. Further information may be obtained from the Publisher.
All questions arising after acceptance of the manuscript, especially those relating to proofs, should be directed to: Elsevier Science Ireland Ltd., Issue Manager J. Biotechnology, Elsevier House, Brookvale Plaza, East Park, Shannon, Co. Clare, Ireland, Tel. + 353-61-709616, Fax + 353-61-709110.
Proofs will be sent to the first-named author of an article, unless an alternative is requested on the title page of the manuscript. They should be checked carefully and returned by airmail within 2 days of receipt. Only printer's errors may be corrected: no changes in or additions to the edited manuscript will be allowed at this stage.
Page charges will not be made.
Reprints may be ordered by filling in and returning to the Publishers the order form sent to the author with the proofs. Twenty five free offprints per contribution will be made available.
Editorial Board
- Chief Editor:
- A. Pühler, Universität Bielefeld, Universitätstrasse 25, D-33615 Bielefeld, Germany; Tel: +49 521 106 5607, Fax: +49 521 106 5626, Email: jbiotech@genetik.uni-bielefeld.de
- Associate Editor Biotechnology:
- M.J.T. Carrondo, Inst. de Biologia Ecxp. e Tecnol, Estaacao Agronomica Nacional, Quinta do Marques, Apt. 12, P-2781--901 Oeiras, Portugal. Tel: +351 21 442 7787, Fax: +351 21 442 1161, Email: mjtc@itqb.unl.pt
- Associate Editor Proteins/Enzymology:
- H. Schwab, Institut für Biotechnologie, Technische Universität Graz, Petersgrasse 12, A-8010 Graz, Austria; Tel: +43 316 8738418, Fax: +43 316 8738434, Email: schwab@biote.tu-graz.ac.at
- Associate Editor Nucleic Acids/Molecular Biology:
- H. Blöcker, Gesellschaft für Biotechnologische Forschung mbH, Genome Analysis, Mascheroder Weg 1, D-38124 Braunschweig, Germany Tel: +49 531 6181220, Fax: +49 531 6181292, Email: bloecker@gbf-braunschweig.de
- Associate Editor Biochemical Engineering/Bioprocess Engineering:
- F. Srienc, Biological Process Technology Inst., University of Minnesota, 240 Gortner Laboratory, 1479 Gortner Av. St. Paul, MN 55108-6106, USA Tel: +1 612 6246774, Fax: +1 612 6251700, Email: fried@biosci.cbs.umn.edu
- Regional Editor for Japan:
- T. Imanaka, Kyoto University, Graduate School of Engineering, Dept. of Synthetic Chemistry and Biological Chemistry, Katsura, Kyoto, 606-8501 Japan. Tel: +81 75 383 2777, Fax: +81 75 383 2778, Email: imanaka@sbchem.kyoto-u.ac.jp
- Editorial Board:
- P. Adlercreutz, Lund, Sweden
M. Aizawa, Tokyo, Japan
A.W. Alfermann, Düsseldorf, Germany
W. Ansorge, Heidelberg, Germany
F.A.M. Asselbergs, Basel, Switzerland
M. Betenbaugh, Baltimore, MD, USA
J.M.S. Cabral, Lisboa, Portugal
Y. Chisti, Palmerston North, New Zealand
W.-D. Deckwer, Braunschweig, Germany
B.W. Dijkstra, Groningen, The Netherlands
M. Domach, Pittsburgh, PA, USA
P.M. Doran, Sydney, Australia
L. Eberl, Freising, Germany
M.W. Fowler, Sheffield, UK
Ch. Hatzis, Woburn, MA, USA
M. Hjortso, Baton Rouge, FL, USA
A. Jungbauer, Vienna, Austria
J. Klein, Braunschweig, Germany
D.S. Kompala, Boulder, CO, USA
E.T. Papoutsakis, Evanston, IL, USA
S.B. Petersen, Aalborg, Denmark
U. Petterson, Uppsala, Sweden
W.J. Quax, Groningen, The Netherlands
R. Rigler, Stockholm, Sweden
M. Sara, Vienna, Austria
T. Scheper, Hannover, Germany
R.D. Schmid, Stuttgart, Germany
B. Sonnleitner, Winterthur, Switzerland
W. Steiner, Graz, Austria
G. Stephanopoulos, Cambridge, MA, USA
C.M. Thomas, Birmingham, UK
M. Uhlén, Stockholm, Sweden
L. Viikari, Finland
R. Wilson, St. Louis, MO, USA
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