期刊名称:INVESTIGATIONAL NEW DRUGS
期刊简介(About the journal)
投稿须知(Instructions to Authors)
编辑部信息(Editorial Board)
About the journal

The development of new anticancer agents is one of the most rapidly changing aspects of cancer research. Investigational New Drugs provides a forum for the rapid dissemination of information on new anticancer agents. The papers published are of interest to the medical chemist, toxicologist, pharmacist, pharmacologist, biostatistician and clinical oncologist. Investigational New Drugs provides the fastest possible publication of new discoveries and results for the whole community of scientists developing anticancer agents. Each issue contains original articles dealing with anticancer drug development. Other sections are devoted to invited review articles and letters to the editor. The journal also affords the opportunity to publish the proceedings of special workshops and symposia devoted to the development of new anticancer agents. Provided they add to the understanding of the investigational agents, the journal is not adverse to publishing clinical trials with negative results. Investigational New Drugs cuts across all the usual lines or subdisciplines, providing a locus for the presentation of relevant investigations and the discussion of critical questions appropriate to the entire field of new anticancer drug development.
Instructions to Authors
Editorial communications and manuscripts should be sent to the editorial office:
Michelle Misner DRUG - Editorial Office Kluwer Academic Publishers 101 Philip Drive Assinippi Park Norwell, MA 02061, USA Telephone: (781) 681-0613 Fax (781) 878-0449 E-mail: Michelle.Misner@wkap.com
The journal welcomes original articles dealing with the development of new anticancer agents. There is no fixed limit on the length of articles, though concise presentation is encouraged. All articles will be reviewed. The journal likewise welcomes letters to the editor, dealing either with material that has previously appeared in the journal or with other topics of concern. Letters should be brief, preferably less than 500 words. They will be reviewed, but their publication will be expedited. From time to time the journal will also publish longer articles of opinion or speculation and review articles on selected topics: these will normally be by invitation, but interested investigators are invited to contact the editor.
Manuscripts submitted to this journal must not be under simultaneous consideration by any other publisher and should not have been published elsewhere in substantially similar form. No part of a paper which has been published by IND may be reproduced or published elsewhere without the written permission of the publisher.
Manuscripts must be submitted in English to the Editorial Office. Please submit one original and three copies, typed double-spaced on 22 cm x 29 cm (8 1/2 in x 11 in) white bond paper. This applies to all parts of the manuscripts, including references, legends, etc. Liberal margins (2.5 cm) should be left at the top and bottom, as well as at the sides. The manuscript should be submitted in the following order: Title page, Summary, Text, References, Tables, Figure Legends, and Figures. Each page, beginning with the summary, should also include the senior authors surname typed in the upper left-hand corner.
Title Page
Include title, full name(s), degree(s), and affiliation(s) of author(s); and a maximum of 6 key words. Add: "Address for offprints: ...", followed by full name and address.
Summary
- Begin on a new page.
- Do not exceed 250 words.
- Metric units and Celsius (Centigrade) temperatures should be used for all measurements.
- Abbreviations should be kept to a minimum and must be explained when they first appear; after the first use, abbreviations alone may be used.
- Standard abbreviations should be used for all measurements (see "Style Manuals").
Text
- The text should follow the summary and begin on a new page, as should References, Tables, and Legends.
- Metric units and Celsius temperatures should be used throughout.
- Abbreviations not defined in the summary should be explained when they first appear in the text.
- If applicable, grant support should be included in the section, "Acknowledgements".
- References should be cited in numerical order, the numbers being placed in parentheses. Citations of personal communications and unpublished data should be avoided unless absolutely necessary. When used, such citations should appear in the text. Only, e.g., ("E.D. Smith, personal communication"), and not in the reference list.
References
- Number in the order in which they appear in the text.
- Abbreviate titles of periodicals according to the style of the Index Medicus.
- Follow the format (arrangement, punctuation) shown below:
Periodicals
1. Gorski J, Toft DO: A receptor molecule for estrogens: isolation from the rat uterus and preliminary characterization. Proc Nat Acad Sci USA 55:1574-1581, 1968 (Please list all authors; do not use "et al.")
Books (edited by someone-other than author of article)
2. McGuire WL, Horwitz KB, De la Garza M: Selecting endocrine therapy in breast cancer. In: Menon KMJ, Reel JR (eds) Steroid Hormone Action and Cancer. Plenum Publ Corp, New York, 1976, pp 28-35
Books (identical author and editor)
3. Berne E: Principles of Group Treatment. Oxford University Press, New York, 1966, p 26
Abstracts
4. Same as periodicals with ("Abstract") following the title.
Tables
- Tables should supplement, not duplicate, the text.
- Tables should be numbered consecutively in Arabic numerals in order of appearance in the text, and typed on separate pages.
- Abbreviations used in a table should be foot-noted (use lower-case letter in parentheses) and explained below the table in the order in which they appear in the table, if they have not been previously used. Any material which is not self-explanatory should also be foot-noted and explained.
Figure Legends
- Be sure that legends and figures correspond.
- Identify all abbreviations used in a figure at the end of each legend, if the abbreviation has not been used in the text.
Figures
- Submit one glossy print (13 x 18 cm, 5 x 7 in) and two photocopies of each figure. If the photocopies are not adequate for evaluation, as may be the case for photomicrographs, submit three glossy prints.
- On the back of each print, indicate number, senior authors surname, and top of illustration; all of this should be written lightly with soft, black pencil.
- Submit written permission from author(s) and publisher for any figure which has been published previously.
- Do not use clips on prints; submit them in an envelope backed by cardboard.
- Any lettering or scale of measurement used in an illustration must be large enough to be legible in the event of half-size reduction.
- Do not send original art-work.
- Photographs in which a patient or other person is identifiable must have written permission from that person. The consent must state specifically what the person is consenting to and what restrictions, if any, the person has placed on the publication of the photograph. All restrictions must be strictly observed.
- Color illustrations are costly and will be charged to the author. Authors should inquire about cost from the publisher before submitting a color illustration.
Manuscript Preparation (Brief Reports)
This format should be used for clinical trials which document no activity for a particular agent or combination of agents or for a submission which the author feels needs only a brief amount of information presented. The manuscript should be no longer than 500 words with a limit of 1 table and 6 references.
Manuscript Preparation (Letters to the Editor)
Letters should follow the general rules laid down above, except that a separate title page and summary are not required. A table or figure may be included if required; if references are needed, they should follow the format given above. The full names and full addresses of the writers should follow the text.
Style Manuals
The following two books are recommended as guides in writing scientific papers; they are particularly useful in providing standard abbreviations for measurements and other scientific terms:
- CBE Style Manual: prepared by the Committee on Form and Style of the Council of Biology Editors, published by the American Institute of Biological Sciences, Arlington, Virginia, 1978.
- Writing Scientific Papers in English: OConnor M, Woodford FD (eds) Elsevier, Amsterdam/Oxford/New York, 1976.
The following book is an extremely valuable general, non-scientific style manual: The Elements of Style: Strunk W Jr, White EB. Macmillan, New York, 1972.
Electronic Delivery
Please send only the electronic version (of ACCEPTED paper) via one of the methods listed below. Note in the event of minor discrepancies between the electronic version and hard copy, the electronic file will be used as the final version.
Via electronic mail
- Please e-mail electronic version to: KAPfiles@wkap.com
- Recommended formats for sending files via e-mail:
- Binary files - uuencode or binhex
- Compressing files - compress, pkzip or gzip
- Collecting files - tar
- The e-mail message should include the author¡®s last name, the name of the journal to which the paper has been accepted, and the type of file (e.g., LATEX or ASCII).
Via anonymous FTPftp: ftp.wkap.com cd: /incoming/production
Send e-mail to KAPfiles@wkap.com to inform Kluwer the electronic version is at this FTP site.
Via disk
- Label a 3.5 inch floppy disk with the operating system and word processing program along with the authors¡® names, manuscript title, and name of journal to which the paper has been accepted.
- Mail disk to:
Kluwer Academic Publishers Desktop Department 101 Philip Drive Assinippi Park Norwell, MA 02061 USA
Any questions about the above procedures please send e-mail to: dthelp@wkap.com
Proofing
Page proofs for articles to be included in a journal issue will be sent in PDF format via e-mail to the contact author for proofing. Corrections should be received back by the Publisher within 72 hours.
Copyright
It is the policy of Kluwer Academic Publishers to own the copyright of all contributions it publishes. To comply with the U.S. Copyright law, authors are required to sign a copyright transfer form before publication. This form returns to authors and their employers full rights to reuse their material for their own purposes. Authors must submit a signed copy of this form with their manuscript.
Offprints
Each group of authors is entitled to 50 free offprints of their paper. Additional offprints may be ordered from the Publisher prior to publication. An order form will be sent to authors with page proof.
Editorial Board
Editor: Eric K. Rowinsky San Antonio, TX, USA
Founding Editor & Associate Editor: Daniel Von Hoff, Tucson, AZ, USA
Associate Editors: S. Gail Eckhardt, Denver, CO; Mace L. Rothenberg, Nashville, TN; Alex Sparreboom, Rotterdam, The Netherlands; Chris H.M. Takimoto, San Antonio, TX; Anthony W. Tolcher, San Antonio, TX
Special Issues Editors: Richard Pazdur, Rockville, MD; Beverly A. Teicher, Indianapolis, IN
Editorial Advisory Board: James L. Abbruzzese, Houston, TX; Alex A. Adjei, Rochester, MN; Jean Pierre Armand, Villejuif, France; Jos¨¦ Baselga, Barcelona, Spain; Daniel R. Budman, Manhasset, NY; Ronald M. Bukowski, Cleveland, OH; James Cassidy, Aberdeen, UK; Hak Choy, Nashville, TN; William S. Dalton, Tampa, FL; R.C. Donehower, USA; Elizabeth Eisenhauer, ON, Canada; Charles Erlichman, Rochester, MN; David R. Gandara, Sacramento, CA; Luca Gianni, Milan, Italy; Stuart A. Grossman, Baltimore, MD; Hagop Kantarjian, Houston, TX; Peter J. Houghton, Memphis, TN; Gary R. Hudes, Philadelphia, PA; Ian R. Judson, Surrey, UK; Scott H. Kaufmann, Rochester, MN; Stanley B. Kaye, Glasgow, UK; John G. Kuhn, San Antonio, TX; Scott M. Lipman, Houston, TX; Patricia M. LoRusso, Detroit, MI; H. Kim Lyerly, Durham, NC; Michael Millward, Camperdown, Australia; Hironobu Minami, Kashiwa, Japan; Peter O'Dwyer, Philadelphia, PA; Roman Perez-Soler, Bronx, NY; Yves G. Pommier, Bethesda, MD; Mark J. Ratain, Chicago, IL; Joel M. Reid, Rochester, MN; Neal Rosen, New York, NY; Eric H. Rubin, New Brunswick, NJ; Nagahiro Saijo, Tokyo, Japan; Hiroshi Sasaki, Tokyo, Japan; Edward A. Sausville, Rockville, MD; Jan H.M. Schellens, Amsterdam, The Netherlands; Said M. Sebti, Tampa, FL; Adrian Mario Senderowicz, Bethesda, MD; Lillian Siu, Toronto, ON; David R. Spriggs, New York, NY; Everett Vokes, Chicago, IL; Jeffrey Weber, Los Angeles, CA; Louis M. Weiner, Philadelphia, PA; Geoffrey R. Weiss, San Antonio, TX; Steven D. Weitman, San Antonio, TX; James K.V. Willson, Cleveland, OH; George Wilding, Madison, WI; John R. Zalcberg, Melbourne, Australia
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