期刊名称:EXPERIMENTAL BIOLOGY AND MEDICINE
期刊简介(About the journal)
投稿须知(Instructions to Authors)
编辑部信息(Editorial Board)
About the journal
http://www.sebm.org/journal.htm
Official Journal of the Society for Experimental Biology and Medicine
SEBM has been a leader in facilitating interaction among biomedical sciences primarily through the publication of Experimental Biology and Medicine (EBM). Published monthly (except August), EBM provides both research and review articles as well as meeting symposia and rapid communications on topics of general interest in endocrinology, molecular biology, nutrition, experimental medicine, physiology, genetics, immunology, biochemistry, microbiology and other biomedical specialties.
Instructions to Authors
http://www.sebm.org/authorinstruct.htm
Experimental Biology and Medicine is particularly appropriate for publication of papers that are multidisciplinary in nature, are of potential interest to a wide audience, and represent experimental medicine in the broadest sense of the term. However, manuscripts reporting novel findings on any topic in the realm of experimental biology and medicine are most welcome. We particularly encourage submission of manuscripts that describe results of clinical studies and results of basic studies with clinical and public health implications. Categories currently listed in EBM are: biochemistry/nutrition; cellular and organ physiology; endocrinology/metabolism; experimental and molecular medicine/oncology/pathology; immunology/microbiology/ virology; molecular, cell, and developmental biology; and pharmacology/toxicology.
Research Articles
Manuscripts are accepted for review with the understanding that the same work has not been and, if accepted by EBM, will not be published elsewhere nor is presently submitted elsewhere; and that its submission for publication has been approved by all of the authors (as confirmed by the covering letter). Unnecessary subdivision of a study into several manuscripts is not acceptable. If any material published previously is included, for clarity or other reasons, this should be indicated with appropriate citation in the manuscript.
One copy of any material that might be regarded as "duplicate publication," such as preliminary reports (including reviews, symposia and proceedings) or other publications (submitted, in press or published) containing data or other material included in the submitted manuscript, must be sent to the Editor when the manuscript is submitted. Clearly label such material so as to avoid any confusion with the submitted manuscript. Normally it is regarded as acceptable to include in a detailed journal material that has been presented previously in summary form in reviews, symposia, or conferences, provided appropriate citation is included.
Brief Communications
Manuscripts describing focused studies that are complete but limited in scope will be published as Brief Communications. This format is intended for the presentation of scientifically sound and novel research in a clear and concise fashion. Do not use section headings in the body of the paper; report methods, results, and discussion in a single section that does not exceed nine (9) pages of double-spaced text with references. Tables and figures must also be kept to a minimum. Formatting should otherwise follow the requirements for Research Articles.
Minireviews
The journal publishes review articles under the section heading "Minireviews." Although there is no page limit, the reviews are generally short (~20 pages of double-spaced text with references). They should reflect the state-of-the-art of the area being reviewed and often include a brief history of the field. There is no need to include an exhaustive literature survey. Emphasis upon a particular hypothesis or point of view or upon the personal opinions or interpretation of the writer or upon the work of the writer's laboratory is appropriate, provided that this focus is clearly indicated in the paper. Most reviews are submitted in response to an invitation from the Editor-in-Chief, and are not subjected to the usual intensive review process prior to publication. Unsolicited reviews are welcome but will be reviewed by the usual process described below.
Comments
The journal, at the Editor-in-Chief's discretion, will publish, under the section heading "Comments," letters or essays from readers discussing articles that have recently appeared in the Journal or other timely topics of interest to the Journal's readership. The author of a letter or essay which is published accepts full responsibility for the contents of the letter. Letters discussing a published article may for example include supporting information, clarifications, criticisms, corrections, alternate interpretations or perspectives. Such letters will be sent to the corresponding author of that article prior to publication. If the corresponding or other author wishes, her/his response will be published together with the original letter. At the discretion of the editor, essays or letters discussing controversial issues may be sent to persons representing alternative viewpoints who will be encouraged to provide responses. If the Editor decides to publish such responses, they will be sent to the original author for comments prior to publication. In some cases, the Editor- in-Chief may send a letter or essay for outside review prior to deciding whether to publish it. The Society reserves the right to edit these communications without materially changing their meaning.
Manuscripts should be written in clear, concise and grammatical English and should conform to the general style of the Journal and the specific instructions listed below. Manuscripts that are not adequately prepared will be returned to the authors, since it is not feasible for the Editors to undertake extensive revision or rewriting. Authors submitting a manuscript do so on the understanding that if it is accepted for publication, copyright in the article, including the right to reproduce the article in all forms and media, shall be assigned exclusively to the Society. The Society will not refuse any reasonable request by an author for permission to reproduce any of their contributions to the Journal. Send requests for permission to reproduce items published in Experimental Biology and Medicine to:
Society for Experimental Biology and Medicine 195 West Spring Valley Avenue. Maywood, NJ 07607-1727 USA
Articles and any other materials published in Experimental Biology and Medicine represent the opinions of the author(s) and should not be construed to reflect the opinions of the Editor(s) or the Society.
SUBMIT FOUR PAPER COPIES and ONE DISK (in Word or Word Perfect) OF MANUSCRIPTS. SEND ONLY ORIGINAL PRINTS OF PHOTOMICROGRAPHS.
Submitted manuscripts and accompanying materials become the property of the Society, and the Society is not responsible for loss or damage to such materials. The manuscript must be accompanied by a covering letter signed by all of the authors; if certain authors cannot sign due to distant geographic location, the letter must state that the non-signing author(s) have read and approved the manuscript. Any person cited in the manuscript as a source of "personal communication" or "unpublished data" must provide signed approval of such citation.
The covering letter should contain names, addresses, telephone and fax numbers and email addresses of at least three scientists with specific expertise for potential use as referees; the Editor-in-Chief is under no obligation to use the suggested referees.
Authors of manuscripts describing original nucleotide or amino acid sequences must submit the sequence to Gen Bank and obtain an accession number from Gen Bank before publication of the manuscript. The accession number should be included in the manuscript as a footnote or in the appropriate figure legend.
When, as a result of reviewers' comments, it is necessary to revise a manuscript, it is recommended that, unless additional studies are required, the authors should resubmit the revised manuscript promptly; a delay of longer than four months may result in the revised manuscript receiving a lower priority.
If you have any questions regarding submission, please contact the Society office:
Tel: (201) 291-9080 Fax: (201) 291-2988 e-mail: sebm@inch.com
All manuscripts should be submitted to:
Dr. Dale R. Romsos, Editor-in-Chief EXPERIMENTAL BIOLOGY AND MEDIICNE 195 West Spring Valley Avenue Maywood, NJ 07607 USA
NOTIFY SEBM AT LEAST ONE MONTH BEFORE CHANGE OF ADDRESS.
Page and Other Charges
1. Changes in proof should be absolutely minimal. Authors will be charged for excessive changes.
2. Colored illustrations can only be published if the authors cover the costs.
3. The authors are expected to pay a part of the cost of publication in the form of a page charge of $50 per page. Manuscripts for which a member of the SEBM is an author are exempt from page charges. (Please provide the name(s) of any SEBM member author(s) when submitting a manuscript). Authors lacking funding from grant or other sources may request a waiver. Requests for a waiver must be received prior to publication and must be countersigned by an appropriate institutional official verifying that no funds are available for paying page charges.
Use of Human and Animal Subjects, etc.
It is the Journal's policy that all studies involving the use of animals be conducted in compliance with applicable laws and regulations as well as the principles expressed in the National Institutes of Health, USPHS, Guide for the Care and Use of Laboratory Animals, and that the studies be conducted on animals that were lawfully acquired. Use of animals must have been approved by the Institution's Animal Care and Use Committee (IACUC) and this must be stated in the Materials and Methods section of the article. If the study was conducted in a jurisdiction where such review is not required, this should be noted in the Materials and Methods section. Studies involving human subjects must conform to the ethical standards set by the Belmont Report, Ethical Principles and Guidelines for the Protection of Human Subjects of Research; must have been reviewed and approved by the appropriate institutional Review Board (IRB); and must be presented in such a manner as to assure preservation of the anonymity of the subjects. It must be stated in the Materials and Methods section of the article that the study had been approved by the responsible IRB and that informed consent was obtained from research subjects or it must be explained why IRB review and /or informed consent were not required. Experiments involving recombinant DNA must have been reviewed and approved as required by applicable laws and regulations.
Financial Support and Conflict of Interest
All grant, contract and industrial support of the work included in the manuscript must be acknowledged in a footnote to the title of the manuscript. Commercial relationships of any of the authors that might be viewed as representing a conflict of interest must be disclosed in a footnote to the applicable author's name. Such disclosure should be made on a separate page as it will not be sent to reviewers or influence editorial decisions but will be included in the published paper.
Corrections
Notice of errors introduced inadvertently into a manuscript during the publication process will be published under the heading "Errata."
Corrections authors may wish to make regarding errors that they introduced into the manuscript or into the data analysis or interpretation will be published under the section heading "Comments," together with any responses by dissenting authors.
Review Process
Manuscripts may be returned to the authors without detailed review if, in the opinion of the Editor-in-Chief, they fall outside the scope of interests of the Journal's readership. In general, two or three reviewers will evaluate each manuscript on the basis of scientific rigor of the experimental design, adequacy of the data, validity of the conclusions, importance and originality of the studies, adequacy of the literature citations, clarity of the presentation, and interest to the Journal's readership.
Manuscripts will be given a quality (priority) ranking by each reviewer; those manuscripts with low priority rankings will not be accepted even though they may have been classed as generally acceptable. If reviewers differ significantly in their opinions, decision will be based on the priority rankings and/or the opinion of an additional reviewer (arbiter). Manuscripts returned after revision based upon reviewers' comments will be sent back to the original reviewers together with the authors' responses.
The reviewers' comments will be held in confidence except as follows: (a) the reviewers' comments may be sent, in whole or in part, to the corresponding author; (b) after revision, each reviewer's comments will be sent, in whole or in part, to the other reviewers of the manuscript; and (c) in the event that there is a significant difference in opinion between or among the reviewers, the manuscript may be sent to an additional reviewer (arbiter) together with the comments, in whole or in part, of the other reviewers. In all cases, anonymity of the reviewers will be maintained.
Style of Manuscripts
1. Manuscripts should be as concise as possible, yet sufficiently detailed to permit critical appraisal, and should generally not exceed 40 typed pages (including tables, charts and references).
2. Manuscripts (including tables, legends and footnotes) should be double or triple spaced. Pages should be numbered consecutively.
3. The first page of the manuscript should contain the complete title of the paper, category for the "Table of Contents" (select from list in the first paragraph of these Instructions), names of authors (without degrees), affiliations (including zip codes), and a running title consisting of no more than 40 characters (including spaces). The second page of the manuscript should give the name, complete address, zip code, telephone and fax numbers, and email address of the author to whom ALL correspondence should be sent ("corresponding author").
4. The Title should be a declarative statement of key findings and should be limited to 15 words. Use of abbreviations in the title should generally be avoided. Research articles should be divided into an Abstract (maximum 300 words), with a list of four to five key words at the end of the Abstract, Introduction, Materials and Methods, Results, and Discussion sections.
5. Figures. All figures should be cited consecutively by Arabic numerals in the text with figure legends typed on a separate sheet. Legends should contain sufficient experimental detail to permit the figures to be interpreted without reference to the text. Units should be clearly indicated in the figures themselves. All figures and illustrations are to be submitted in such form as to permit photographic reproduction without retouching or redrawing. This includes the lettering, which is reproduced as part of the figure and is not set in type. Send only original prints of photomicrographs. Line drawings should be no larger than 8.5 x 11.5 inches overall (21 x 27.5 cm). The lettering should be large enough to allow a reduction of two thirds. High quality glossy prints are acceptable.
6. Tables. These should be numbered with Arabic numerals and cited consecutively in the text. Each table should be titled and double-spaced on a separate sheet. Refer to current issues of the EBM for the acceptable style of tables. The title of each table should clearly indicate the nature of the contents, and sufficient experimental detail should be included in footnotes to the entries in the table to permit the reader to interpret the results without reference to the text. Units must be clearly indicated for each of the entries in the table.
7. Footnotes. Footnotes in the text should be identified by superscripts consisting of Arabic numerals and should be typed on a separate sheet; footnotes in the tables should be identified by superscript lowercase letters a, b, c, etc., and placed at the bottom of the table.
a. Acknowledgments should be typed on a separate page and placed at the end of the text pages.
8. References.
a. Citations should be used to provide appropriate attribution and credit to previous investigators. Extensive citation should be avoided, if possible, while adhering to the applicable conventions of the scientific community. Authors are responsible for obtaining permission to reproduce from the appropriate sources cited in the text.
b. References should be arranged numerically at the end of the manuscript and cited in the text with Arabic numerals in parentheses, set on the text line. The references should be numbered consecutively in order of their citation.
Abbreviations of journal titles should follow the style used in Index Medicus. Please follow the style of capitalization and punctuation illustrated by the following examples:
1. Wang BC, Bettice JA, Brown EB Jr. Effect of body temperature on salicylate-induced hyperventilation. Proc Soc Exp Biol Med 174:102-106,1983.
2. Abramson DI. Circulation in the Extremities. New York: Academic Press, p000, 1967.
3. Langford MP, Weigent DA, Stanton GJ, Baron S. Virus plaque-reduction assay for interferon: Miroplaque and regular macroplaque reduction assay. In: Pestka S, Ed. Methods in Enzymology. New York: Academic Press, Vol Part A 78: p000, 1981.
4. Hylden JL, Wilcox GL. Intrathecal morphine in mice: A new technique. Eur J Pharmacol (in press).
c. "Personal communication," "unpublished," and "submitted" must be excluded from the reference list and cited in a footnote. If a manuscript being cited has been accepted for publication, include it in the reference list, giving journal, year, etc., as available. In general, citation of numerous abstracts is discouraged, although acceptable if necessary to provide proper attribution or credit.
9. Trade name, popular name or abbreviation when first used must be preceded by the chemical, scientific or technical name; thereafter, any of these names or abbreviations may be used. Trade names should begin with a capital letter. Structural formulas of chemicals should be used only when absolutely necessary. Abbreviations used should generally be those listed at the end of this Notice of Contributors. Units of weights, measures, etc., when used in conjunction with numerals, should be abbreviated and unpunctuated, e.g., 6 R, 3 g, 5 ml, 8%. The metric system for weights and measurement, degrees Celsius for temperature, and the 24-hour clock (e.g., 0500h) to express time should be used.
Section Headings
On the title page of your manuscript, indicate a section that is appropriate for your paper. Categories are listed in the first paragraph of these instructions.
Abbreviations Contributors are requested to use the following abbreviations:
calorie cal centimeter cm counts per minute cpm cubic centimeter cm3 Curie Ci degree Celsius (centigrade) °C diameter diam gram g inside diameter i.d. intramuscular im intraperitoneal ip intravenous iv kilocalorie kcal kilogram kg liter spell out meter m microliter µl micrometer µm milligram mg milliliter ml millimeter mm milliosmole mOsm molal (concentration) m molar (concentration) M mole spell out molecular weight mol wt nanogram ng nanometer nm normal (concentration) N osmole Osm outside diameter o.d. parts per million ppm percent % picogram pg revolutions per minute rpm second sec specific activity sp act square centimeter cm2 square meter m2 subcutaneous sc volt V volume vol
Editorial Board
Editor-In-Chief, Dale R. Romsos, PhD Michigan State University
Associate Editors
James L. Caffrey, PhD University of North Texas HSC
Mark L. Failla, PhD,The Ohio State University
H. Rex Gaskins, PhD, University of Illinois
M. Eric Gershwin, MD, University of California, Davis
Joseph P. Grande, MD, PhD, Mayo Clinic
Allyn C. Howlett, PhD, North Carolina Central University
CATEGORIES
Biochemistry/Nutrition Nancy Auestad, PhD, Abbott Laboratories Joseph Lee Beverly, PhD, University of Illinois Randal K. Buddington, Phd, Mississippi State University Roderick H. Dashwood, PhD, Oregon State University Cidy D. Davis, PhD, National Cancer Institute Ruth B.S. Harris, PhD, The University of Georgia Earl Harrison, PhD, USDA, Agricultural Research Service Susan M. Hutson, PhD, Wake Forest University Linda Hyman, PhD, Tulane University Y. James Kang, PhD, University of Louisville Xingen Lei, PhD, Cornell University Simin N. Meydani, PhD, DVM, Tufts University Philip G. Reeves, PhD, USDA Grand Forks Human Nutrition Research Center Martin J. Ronis, PhD, Arkansas Children's Nutrition Center A. Catherine Ross, PhD, Pennsylvania State Univeristy Sue A. Shapses, PhD, Rutgers University Neil F. Shay, PhD, University of Notre Dame Tsunenobu Tamura, MD, University of Alabama at Birmingham Carla Taylor, PhD, University of Manitoba Gary E. Truett, PhD, University of Tennessee Rosemary C. Wander, PhD, The University of North Carolina at Greensboro
Cellular and Organ Physiology Nicolas G. Bazan, MD, PhD, Louisiana State University Scott T. Brady, PhD, University of Texas Southwestern Medical Center Oscar A. Candia, MD, Mount Sinai School of Medicine H. Fred Downey, PhD, University of North Texas HSC Jorge Fischbarg, MD, PhD, Columbia University Peter Reinach, PhD, State University of New York, NYC William S. Rosenthal, PhD, New York Medical College Randy S. Sprague, MD, Saint Louis University Paul M. Stein, PhD, Medtronic, Inc, Minneapolis
Endocrinology/Metabolism C. Richard Barb, PhD, USDA< ARS Terry R. Brown, PhD, Johns Hopkins University V. Daniel Castracane, PhD, Texas Tech University Guatam Chaudhuri, MD, PhD, University of California, Los Angeles Richard E. Falvo, PhD, The University of North Carolina at Chapel Hill Geula Gibori, PhD, University of Illinois at Chicago Arthur Gutierrez-Hartmann, MD, University of Colorado HSC David Hurley, PhD, Tulane University Gary L Jackson, PhD, University of Illinois C. Ronald Kahn, MD, Harvard University Harold G. Klemcke, PhD, USDA, U.S. Meat Animal Research Center Holly A. LaVoie, PhD, Univeristy of South Carolina Michael C. Moore, PhD, Arizona State University Fred Naftolin, PhD, MD, Yale University Mary Ann Ottinger, PhD, University of Maryland Ei Terasawa, PhD, University of Wisconsin Li-yuan Yu-Lee, PhD, Baylor College of Medicine
Experimental and Molecular Medicine/Oncology/Pathology S. Jill James, PhD, National Center for Toxicological Research John E. Moulder, PhD, Medical College of Wisconsin Miriam C. Poirier, PhD, National Cancer Institute Robert L. Reddick, MD, University of Texas HSC at San Antonio J. Koudy Williams, PhD, DVM, Wake Forest University
Immunology/Microbiology/Virology Richard J. Ablin, PhD, Innapharma, Inc, Park Ridge, NJ Aftab A. Ansari, PhD, Emory University Melinda A. Beck, PhD, University of North Carolina, Chapel Hill Jerry K. Davis, PhD, DVM, University of Florida, Gainesville Kenneth Dorshkind, PhD, University of California, Los Angeles James G. Fox, DVM, Massachusetts Institute of Technology Brian L. Kotzin, MD, University of Colorado Yeuda Shoenfeld, MD, Chaim Sheba Medical Center, Israel Leonard D. Shultz, PhD, The Jackson Laboratory Henk E. Vietor, MD, PhD, Academy Ziekenhuis Nijmegen, The Netherlands
Molecular, Cell and Developmental Biology
Henry J. Baker, DVM, Auburn Univeristy Ella Englander, PhD, University of Texas Medical Branch, Galveston Jeremiah T. Herlihy, PhD, University of Texas, San Antonio Chad Oh, PhD, Harbor-UCLA Medical Center, Torrance, California Rhoda Reddix, PhD, Louisiana State University John P. Richie, Jr, PhD, American Health Foundation George J. Wolff, PhD, Little Rock, Arkansas
Pharmacology/Toxicology George C.Y. Chiou, PhD, Texas A&M University Michael J. Forster, PhD, University of North Texas HSC Mustafa F. Lokhandwala, PhD, University of Houston Stanley T. Omaye, PhD, University of Nevada William Slikker, Jr, PhD, Nat'l Center for Toxicological Research J. Randy Strong, PhD, University of Texas HSC, San Antonio
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