期刊名称：CURRENT DRUG METABOLISM
 期刊简介(About the journal)
投稿须知(Instructions to Authors)
编辑部信息(Editorial Board)
About the journal
Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism and disposition. Each issue of the journal contains a series of timely in-depth reviews written by leaders in the field covering a range of current topics in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments. The journal covers the following areas:
In vitro systems including CYP-450, enzyme induction and inhibition; Drug-drug interactions and enzyme kinetics; Pharmacokinetics /toxicokinetics / species scaling and extrapolations; P-glycoprotein and transport carriers; Target organ toxicity and inter individual variability; Drug metabolism and disposition studies. Extrahepatic metabolism; Phase I and Phase II metabolism. Recent developments for the identification of drug metabolites and adducts. Identification of drug metabolites and adducts.
Instructions to Authors
Manuscripts should be submitted to the Editor-in-Chief without prior invitation at the following address:
Dr. Chandra Prakash,
Editor-in-Chief, Current Drug Metabolism,
Global Research and Development,
Pfizer, Inc., Eastern Point Road,
Groton, CT 063340, USA;
Phone: +1-860-441-6415;
Fax: +1-860-441-4109;
Email: chandra_prakash@groton.pfizer.com
It is advisable that authors first submit an abstract to the Editor-in-Chief prior submitting the full manuscript. The submitted abstract should outline the intended contents and coverage of their article. For full review articles, the manuscript, written in English, should not exceed 70 pages in length (ca. 30 printed pages) and for mini-reviews a maximum of 40 pages in length (ca. 15 printed pages). The manuscript should be typed in double-spacing throughout on A-4 or American quarto paper. Dot matrix print or any print that is difficult to read is unacceptable. Two copies of the manuscript must accompany the original (along with a passport size black and white photograph of the author and a computer disk) and should be sent to the Editor-in-Chief at his address. All pages should be numbered. Abbreviations should be defined the first time that they are used in the manuscript and a list of abbreviations used should be provided.
Manuscript Organisation: The manuscript should be divided as: Title page, abstract and the main text. The text may be subdivided further according to the areas to be discussed. This should be followed by the Acknowledgement (if any) and Reference sections. The first page should contain the title, the authors names (initials and surname only), with an asterisk in front of the name of the principal author.
Abstract: The abstract should not exceed 250 words and it should condense the essential features of the review article, with the focus on the major advances in the field.
Key Words: Authors must supply up to eight key words along with their manuscript.
Text: The main text should begin on a separate page and it may be subdivided into separate sections. The review article should mention any previous important reviews in the field and contain a comprehensive discussion starting with the general background of the field. It should then go on to discuss the salient features of recent developments. The authors should avoid presenting material which has already been published in a previous review. The reference numbers should be given in square brackets in the text. Acknowledgements should be kept to a minimum.
Tables:
* Data Tables should be submitted in Microsoft Excel or in Microsoft Word table format.
* Each table should include a title/caption explaining what the table shows. Detailed legends may then follow.
* Tables should be given on separate pages with indications on the left hand margin to the text, as to the appropriate placement of the tables.
* Tables should not contain vertical rules.
* Columns and rows of data should be made visibly distinct by ensuring the borders of each cell display as black lines.
* Tables should be numbered consecutively in order of their citation in the body of the text, with Arabic numerals.
* If a reference is cited in both the table and text, insert a lettered footnote in the table to refer to the numbered reference in the text.
* Tabular data provided as additional files can be submitted as an Excel spreadsheet.
Figures / Illustrations:
All authors must strictly follow the guidelines below for preparing illustrations for publication in Current Drug Metabolism.
Editorial Requirements:
The quality of the illustrations printed in the journal largely depends on the quality of the figures/illustration provided by the author. In preparing artwork or graphics for publication, keep in mind the following points.
* Submit the original artwork or a photographic print of the original for publication.
* Do not submit photocopies. (Hardcopy submission requirement)
* Illustrations should be provided as separate files, not embedded in the text. (Hardcopy submission requirement).
* Remove all color from graphics except for those illustrations (Greyscale), which are intended to be printed in color.
* Good quality of hardcopy originals are a requirement.
* Figures/illustrations cannot be modified or enhanced by the journal production staff.
* Figures should be referred to as ¡°Fig. (1)¡±, ¡°Fig. (2)¡± etc. in the text with figure numbers in bold within round bracket.
* Revised manuscripts should contain a complete set of artwork and photographs.
Technical Details:
* Figures should be provided on high quality, white, smooth opaque paper. (Hardcopy requirement)
Format & Resolution:
* The following file formats can be accepted. (Preference in order of appearance): PDF, TIFF, JPEG, GIF
* Illustrations must fit a single or double column format on the journal page, according to the following guideline below:
HEIGHT
WIDTH
SINGLE COLUMN
24 cm (max)
8.5 cm (max)
DOUBLE COLUMN
24 cm (max)
18 cm (max)
* Whenever possible, submit graphics that do not have to be reduced to fit the standard figure size.
* Use the best resolution available (hardcopy submission requirement). For online submission the maximum resolution is 300 dpi.
* Avoid textures and shadings giving a three-dimensional effect to the illustration.
* Symbols and lettering in the illustration should be of similar size.
* Smaller lettering is used.
* Font: Times New Roman or Helvetica is preferable. Font size: 10pt (maximum)
* Line drawings should have clear and sharp lines and should be of uniform density. Moreover, lines should be continuous without any breaks.
* Do not use lines thinner than 1 point.
Color Figures/Illustrations:
* Free colored artwork will only be published if the color is deemed scientifically necessary by the Editor-in-Chief.
* One color plate will be published free of charge in each article. The cost for the first additional published page of color figures is US$ 605; the second additional page will be for US$ 440, and each subsequent page for $ 303.
* Color figures should be supplied in CMYK not RGB colors.
* Required resolution for online submission is 300 dpi. In case of hardcopy submission, please use the maximum resolution available.
Photographs:
Submit high-contrast prints that are of single- or double-column width so that they will not have to be reduced when printed. Negatives are not acceptable. However, in case of hardcopy submission, color illustrations and plates can be published from 35 mm color slides.
Chemical Structures: Chemical structures must be prepared according to the guidelines below.
Structures should be prepared using a suitable drawing program e.g. ChemDraw and provided as separate file, submitted both on disk and in printed formats.
Numbers in bold should identify all chemical structure. If a name is also used to describe the compound, the associated number in bold should be in parenthesis, e.g. ¡°compound (1)¡±.
Structure Drawing Preferences:
[As according to the ACS style sheet]
Drawing Settings:
Chain angle 120o
Bond spacing 18% of width
Fixed length 14.4 pt (0.500cm, 0.2in)
Bold width 2.0 pt (0.071cm, 0.0278in)
Line width 0.6 pt (0.021cm, 0.0084in)
Margin width 1.6 pt (0.096cm)
Harsh spacing 2.5 pt (0.088cm, 0.0347in)
Text settings:
Font Times New Roman / Helvetica
Size 10pt
Under the Preference Choose:
Units points
Tolerances 3 pixels
Under Page Setup Use:
Paper US letter
Scale 100%
References: All references must be numbered in the text in square brackets, e.g. [4], or [7,10-15], in order of citation in the text. Titles of journals are abbreviated according to Chemical Abstract Service Source Index,
Examples:
[1] Gibbs, M.A.; Thummel, K.E.; Shen, D.D. and Kunze, K.L. (1999) Drug Metab. Dispos., 27(2), 180-187.
[2] Meyer, M.C.; Straughn, A.B.; Mhatre, R.M.; Shah, V.P.; Williams, R.L. and Lesko L.J. (1998) Pharm. Res., 15(11), 1787-1791.
[3] Working, P.K. (1992) in Protein Pharmacokinetics and Metabolism, (Ferraiolo, B.L.; Mohler, M.A. and Gloff, C.A. Eds.), Plenum Press, New York, pp. 73-92.
Editorial Board
A. Baumann (Schering AG, Berlin, GERMANY)
James Baxter (Pfizer Central Research, Groton, CT, USA)
Ian Blair (University of Pennsylvania, Philadelphia, PA, USA)
John Cashman (Human BioMol. Research Inst., San Diego, CA, USA)
Volker Fischer (Novartis Pharmaceuticals, East Hanover, NJ, USA)
David J. Greenblatt (Tufts University, Boston, MA, USA)
Richard Kim (Vanderbilt University, Nashville, TN, USA)
Jiunn Lin (Merck Research Laboratories, West Point, PA, USA)
Allan Rettie (University of Washington, Seattle, WA, USA)
David Riddick (University of Toronto, Ontario, CANADA)
Thomas Rushmore (Merck Research Laboratories, West Point, PA, USA)
Dennis Smith (PGRD, Sandwich Kent, UK)
Philip C. Smith (University of North Carolina, Chapel Hill, NC, USA)
Yuichi Sugiyama (University of Tokyo, Tokyo, Japan)
Steven Tannenbaum (MIT Cambridge, MA, USA)
Geoffrey Tucker (University of Sheffield, Sheffield, UK)
Jack Uetrecht (University of Toronto, Toronto, CANADA)
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