期刊名称：CLINICAL & EXPERIMENTAL METASTASIS
 期刊简介(About the journal)
投稿须知(Instructions to Authors)
编辑部信息(Editorial Board)
About the journal
Aims & Scope
Clinical & Experimental Metastasis is an international, multidisciplinary journal devoted to the rapid publication of fundamental advances in both basic and applied metastasis research.
The Journal's scope encompasses all aspects of metastasis research, whether laboratory-based, experimental or clinical and therapeutic. It covers such areas as molecular biology, pharmacology, tumour biology, and clinical cancer treatment (with all its subdivisions of surgery, chemotherapy and radio-therapy as well as pathology and epidemiology) insofar as these disciplines are concerned with the Journal's core subject of metastasis formation, prevention and treatment.
While the emphasis is on speed of publication, with papers normally published within 12 weeks of acceptance, the Editors rigorously maintain refereeing standards to ensure only the highest quality research is selected for publication.
Instructions to Authors
Manuscript submission
Kluwer Academic Publishers request the submission of manuscripts and figures in electronic form in addition to a hard-copy printout. The preferred storage medium for your electronic manuscript is a 3 1/2 inch diskette. Please label your diskette properly, giving exact details on the name(s) of the file(s), the operating system and software used. Always save your electronic manuscript in the word processor format that you use; conversions to other formats and versions tend to be imperfect. In general, use as few formatting codes as possible. For safety‘s sake, you should always retain a backup copy of your file(s). After acceptance, please make absolutely sure that you send the latest (i.e., revised) version of your manuscript, both as hard-copy printout and on diskette (submission in electronic form of the final version of your article is compulsory).
Kluwer Academic Publishers prefer articles submitted in word processing packages such as MS Word, WordPerfect, etc. running under operating systems MS DOS, Windows and Apple Macintosh, or in the file format LaTeX. Articles submitted in other software programs can also be accepted.
For submission in LaTeX, Kluwer Academic Publishers have developed a Kluwer LaTeX class file, which can be downloaded from: http://www.wkap.nl/authors/jrnlstylefiles/
Use of this class file is highly recommended. Do not use versions downloaded from other sites. Technical support is available at: texhelp@wkap.nl. If you are not familiar with TeX/LaTeX, the class file will be of no use to you. In that case, submit your article in a common word processor format.
For the purpose of reviewing, articles for publication should be submitted as hard-copy printout (in triplicate) and on diskette, to any of the following Editorial Offices: G. Nicholson
Clinical & Experimental Metastasis
(US Editorial Office)
Institute for Molecular Medicine
15162 Triton lane
Huntington Beach
CA 92649-1041, U.S.A.
Tel: (+1) 714 903 2900
Fax: (+1) 714 739 2082
E-mail: gnicimm@ix.netcom.com
S.A. Eccles
Clinical & Experimental Metastasis
(European Editorial Office)
Institute of Cancer Research
Section of Cancer Therapeutics
McElwain Laboratories
15 Cotswold Road, Sutton
Surrey SM2 5NG, UK
Tel: (+44) 181 643 8901, ext. 4210
Fax: (+44) 181 643 0223
E-mail: suzan@icr.ac.uk
T. Irimura
Clinical & Experimental Metastasis
(Asia & Far East Editorial Office)
Department of Cancer Biology and Molecular Immunology
Faculty of Pharmaceutical Sciences
University of Tokyo
Hongo 7-3-1, Bunkyo-ku
Tokyo 113, Japan
Tel: (+81) 3 58414870
Fax: (+81) 3 58414879
E-mail: irimura@mol.f.u.-tokyo.ac.jp
Ethics
The journal upholds the principles outlined in the Declaration of Helsinki (1964) and expects that investigations concerning work on humans will have been performed in accordance with these principles. Papers reporting human experimentation must include a statement that they were carried out with the approval of an ethical committee.
Furthermore, the journal endorses the most humane treatment of animals in the conduct of scientific studies. For animal experimentation reported in this journal, it is expected that the investigators will have observed the Interdisciplinary Principles and Guidelines for the Use of Animals in Research, Marketing and Education issued by the New York Academy of Sciences?Ad Hoc Committee on Animal Research. Copies are available from the Marketing Department, New York Academy of Sciences, 2 E. 63rd Street, New York, NY 10021-7289, USA. Only results of those experiments, including photographic presentation of data, in which proper attention has been given to ethical considerations towards animals will be published. The Editors reserve the right to reject a paper with questionable ethical justification.
Manuscript presentation
The journal‘s language is English. British English or American English spelling and terminology may be used, but either one should be followed consistently throughout the article. Manuscripts should be printed or typewritten on A4 or US Letter bond paper, one side only, leaving adequate margins on all sides to allow reviewers?remarks. Please double-space all material, including notes and references. Quotations of more than 40 words should be set off clearly, either by indenting the left-hand margin or by using a smaller typeface. Use double quotation marks for direct quotations and single quotation marks for quotations within quotations and for words or phrases used in a special sense.
Number the pages consecutively with the first page containing:
- running head (shortened title)
- title
- author(s)
- affiliation(s)
- full address for correspondence, including telephone and fax number and e-mail address
Abstract
Please provide a short abstract of 100 to 250 words. The abstract should not contain any undefined abbreviations or unspecified references.
Key Words
Please provide 5 to 10 key words or short phrases in alphabetical order.
Abbreviations
Abbreviations and their explanations should be collected in a list.
Article types
In addition to research articles, short review articles are also welcomed, although it is recommended that authors first contact one of the Editors for advice on the suitability of the proposed topic and for further instructions.
Symbols and units
Please use SI (Systeme International) units.
Figures and tablesSubmission of electronic figures
In addition to hard-copy printouts of figures, authors are requested to supply the electronic versions of figures in either Encapsulated PostScript (EPS) or TIFF format. Many other formats, e.g., Microsoft Postscript, PiCT (Macintosh) and WMF (Windows), cannot be used and the hard copy will be scanned instead.
Figures should be saved in separate files without their captions, which should be included with the text of the article. Files should be named according to DOS conventions, e.g., ‘figure1.eps? For vector graphics, EPS is the preferred format. Lines should not be thinner than 0.25pts and in-fill patterns and screens should have a density of at least 10%. Font-related problems can be avoided by using standard fonts such as Times Roman and Helvetica. For bitmapped graphics, TIFF is the preferred format but EPS is also acceptable. The following resolutions are optimal: black-and-white line figures - 600 - 1200 dpi; line figures with some grey or coloured lines - 600 dpi; photographs - 300 dpi; screen dumps - leave as is. Higher resolutions will not improve output quality but will only increase file size, which may cause problems with printing; lower resolutions may compromise output quality. Please try to provide artwork that approximately fits within the typeset area of the journal. Especially screened originals, i.e. originals with grey areas, may suffer badly from reduction by more than 10-15%. Avoiding problems with EPS graphics
Please always check whether the figures print correctly to a PostScript printer in a reasonable amount of time. If they do not, simplify your figures or use a different graphics program.
If EPS export does not produce acceptable output, try to create an EPS file with the printer driver (see below). This option is unavailable with the Microsoft driver for Windows NT, so if you run Windows NT, get the Adobe driver from the Adobe site (www.adobe.com).
If EPS export is not an option, e.g., because you rely on OLE and cannot create separate files for your graphics, it may help us if you simply provide a PostScript dump of the entire document. How to set up for EPS and PostScript dumps under Windows
Create a printer entry specifically for this purpose: install the printer ‘Apple Laserwriter Plus?and specify ‘FILE?as printer port. Each time you send something to the ‘printer?you will be asked for a filename. This file will be the EPS file or PostScript dump that we can use.
The EPS export option can be found under the PostScript tab. EPS export should be used only for single-page documents. For printing a document of several pages, select ‘Optimise for portability?instead. The option ‘Download header with each job?should be checked. Submission of hard-copy figures
If no electronic versions of figures are available, submit only high-quality artwork that can be reproduced as is, i.e., without any part having to be redrawn or re-typeset. The letter size of any text in the figures must be large enough to allow for reduction. Photographs should be in black-and-white on glossy paper. If a figure contains colour, make absolutely clear whether it should be printed in black-and-white or in colour. Figures that are to be printed in black-and-white should not be submitted in colour. Authors will be charged for reproducing figures in colour.
Each figure and table should be numbered and mentioned in the text. The approximate position of figures and tables should be indicated in the margin of the manuscript. On the reverse side of each figure, the name of the (first) author and the figure number should be written in pencil; the top of the figure should be clearly indicated. Figures and tables should be placed at the end of the manuscript following the Reference section. Each figure and table should be accompanied by an explanatory legend. The figure legends should be grouped and placed on a separate page. Figures are not returned to the author unless specifically requested.
In tables, footnotes are preferable to long explanatory material in either the heading or body of the table. Such explanatory footnotes, identified by superscript letters, should be placed immediately below the table.
Section headings
First-, second-, third-, and fourth-order headings should be clearly distinguishable but not numbered.
Appendices
Supplementary material should be collected in an Appendix and placed before the Notes and Reference sections.
Notes
Please use endnotes rather than footnotes. Notes should be indicated by consecutive superscript numbers in the text and listed at the end of the article before the References. A source reference note should be indicated by means of an asterisk after the title. This note should be placed at the bottom of the first page.
Cross-referencing
In the text, a reference identified by means of an author‘s name should be followed by the reference number in square brackets. When there are more than two authors, only the first author‘s name should be mentioned, followed by ‘et al.? Examples:
Winograd [1]
Bullen and Bennett [2]
Acknowledgements
Acknowledgements of people, grants, funds, etc. should be placed in a separate section before the References.
References
References to books, journal articles, articles in collections and conference or workshop proceedings, and technical reports should be listed at the end of the article in numbered order following the Vancouver style (see examples below). Articles in preparation or articles submitted for publication, unpublished observations, personal communications, etc. should not be included in the reference list but should only be mentioned in the article text (e.g., T. Moore, personal communication).
References to books should include the author‘s name (when there are more than four authors, list only the first three, followed by ‘et al.?; year of publication; title; page numbers where appropriate; publisher; place of publication in the order given in the example below.
1. Celio MR, Pauls T, Schwaller B. Guidebook to the Calcium-Binding Proteins. Oxford: Oxford University Press 1996; 3-15.
References to articles in an edited collection should include the author‘s name; year of publication; article title; editor‘s name; title of collection; first and last page numbers; publisher; place of publication, in the order given in the example below.
1. Ormerod MG. Analysis of DNA - general methods. In Ormerod MH (ed): Flow Cytometry: A Practical Approach, 2nd edition. Oxford: Oxford University Press 1989; 119-35.
References to articles in periodicals should include the author‘s name; year of publication; article title; abbreviated title of periodical; volume number (issue number where appropriate); first and last page numbers, in the order given in the example below.
1. Timar J, Trikha M, Szekeres et al. Expression and function of the high affinity 11b-3 integrin in murine melanoma cells. Clin Exp Metastasis 1998; 16 (5): 437-45.
Proofs
Proofs will be sent to the corresponding author by e-mail (if no e-mail address is available or appears to be out of order, proofs will be sent by regular mail).
Your response, with or without corrections, should be sent within 72 hours. Please do not make any corrections to the PDF file.
Minor corrections (+/- 10) should be sent as an e-mail attachment to: proofscorrection@wkap.nl. Always quote the four-letter journal code and article number and the PIPS No. from your proof in the subject field of your e-mail.
Extensive corrections must be clearly marked on a printout of the PDF file and should be sent by first-class mail (airmail overseas).
Offprints
Twenty-five offprints of each article will be provided free of charge. Additional offprints (both hard copies and PDF files) can be ordered by means of an offprint order form supplied with the proofs.
Page charges and colour figures
No page charges are levied on authors or their institutions. Colour figures are published at the author‘s expense only.
Copyright
Authors will be asked, upon acceptance of an article, to transfer copyright of the article to the Publisher. This will ensure the widest possible dissemination of information under copyright laws.
Permissions
It is the responsibility of the author to obtain written permission for a quotation from unpublished material, or for all quotations in excess of 250 words in one extract or 500 words in total from any work still in copyright, and for the reprinting of figures, tables or poems from unpublished or copyrighted material.
Additional information
Additional information can be obtained from: Clinical & Experimental Metastasis
Kluwer Academic Publishers
P.O. Box 17
3300 AA Dordrecht
The Netherlands
Tel.: +31-78-6576392
Fax: +31-78-6576377
Internet http://www.wkap.nl
Editorial Board
Editor:
Suzanne A. Eccles
Institute of Cancer Research, Sutton, UK
Garth L. Nicolson
The Institute for Molecular Medicine, Huntington Beach, CA, USA
Tatsuro Irimura
Dept. of Cancer Biology & Molecular Immunology, University of Tokyo, Japan
Kurt Hellmann
Editor Emeritus, UK
Editorial Board:
A. Albini, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy; W. Birchmeier, Max-Delbrück-Zentrum, Berlin, Germany; R. Bresalier, Henry Ford Hospital, Detroit, MI, USA; P. Brodt, Royal Victoria Hospital, Montreal, Canada; A. Chambers, University of Texas MD Anderson Cancer Center, Houston, USA; L. Eisenbach, Weizmann Institute of Science, Rehovot, Israel; I.J. Fidler, University of Texas MD Anderson Cancer Center, Houston, USA; ? Fodstad, Institute of Cancer Research, Oslo, Norway; J. M. Foidart, Universit?de Liège, Belgium; G. Gasparini, Azienda Complesso Ospedaliero, Rome, Italy; R. Giavazzi, Mario Negri Institute, Bergamo, Italy; A.L. Harris, Oxford Radcliffe Hospital, Headington, UK; I.R. Hart, Imperial Cancer Research Fund, London, UK; R.P. Hill, Ontario Cancer Institute, Toronto, Canada; R.S. Kerbel, Sunnybrook Health Sciences Centre, Toronto, Canada; L.A. Liotta, National Cancer Institute, Bethesda, MD, USA; M. Mareel, University Hospital, Ghent, Belgium; M. Polette, INSERM, Universit?de Reims, France; R. Radinsky, University of Texas, Houston, USA; A. Raz, Michigan Cancer Foundation, Detroit, USA; H. Sato, Cancer Research Institute, Kanazawa, Japan; V. Schirrmacher, Deutsches Krebsforschungszentrum, Heidelberg, Germany; M. Seiki, Institute of Medical Science, Tokyo, Japan; J.P. Thiery, Institut Curie, Paris, France; J. Timár, Semmelweiss University of Medicine, Budapest, Hungary; E. Thompson, St. Vincent's Institute of Medical Research, Melbourne, Australia; T. Tsuruo, Institute of Molecular and Cellular Biosciences, Tokyo, Japan; G.A. Turner, University of Newcastle upon Tyne, UK; D.R. Welch, Jake Gittlen Cancer Research Institute, Hershey, PA, USA
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