期刊名称：CELL DEATH AND DIFFERENTIATION ISSN： 1350-9047 版本： SCI-CDE 出版频率： Monthly 出版社： SPRINGERNATURE, CAMPUS, 4 CRINAN ST, LONDON, ENGLAND, N1 9XW   出版社网址： http://www.nature.com/ 期刊网址： http://www.nature.com/cdd/index.html 影响因子： 15.828 主题范畴： BIOCHEMISTRY & MOLECULAR BIOLOGY;    CELL BIOLOGY 期刊简介(About the journal)    投稿须知(Instructions to Authors)    编辑部信息(Editorial Board)    About the journal Cell Death and Differentiation is a journal devoted to the cell biology, molecular biology and biochemistry of cell death and differentiation, both in normal tissue regulation and in disease. To this end, Cell Death and Differentiation provides a unified forum for scientists as well as clinicians. It is committed to the rapid publication of high quality original papers that relate to these subjects, together with topical, usually solicited, reviews, meeting reports, editorial correspondence and occasional commentaries on controversial and scientifically informative issues. Instructions to Authors Submission of manuscripts (Full Papers) Four copies of the manuscript, with one original set (and three copies) of artwork, should be submitted to one of the Editorial Offices. Authors whose first language is not English are requested to have their manuscripts checked carefully for linguistic correctness before submission. To speed up the reviewing process, authors are encouraged to submit by e-mail. For full electronic submission instructions (i.e. by disc or e-mail) please see below. Manuscripts will not be returned. In the case of electronic submission, i.e. via e-mail or by disc, please DO NOT send printed copies by post. A printed copy, as well as a disc will be requested only if the manuscript is accepted for publication. Submission by disc Authors who wish to submit their manuscripts by disc should send their manuscript, with artwork saved in JPEG or Tiff format to one of the Editorial offices. For instructions on the required file types, please see the 'Organisation of Manuscripts' section below. Submission via e-mail Authors should e-mail the manuscript as a single PDF file that must not exceed 5MB. Individual documents in the preferred file format will be requested later on, in the event that the manuscript is accepted for publication. Rome Mauro Piacentini, Gerry Melino, Peter H Krammer, Richard A Knight, Seamus Martin, Guido Kroemer c/o Gerry Melino IDI-IRCCS Laboratory Department of Experimental Medicine F153/D26, University of Rome 'Tor Vergata', Via Montpellier 1, 00133 Rome, Italy Tel: +39 06 20427299 Fax: +39 06 20427290 E-mail: cell.death.differ@uniroma2.it San Diego Doug R Green, Guy Salvesen, Carol J Thiele, Barbara A Osborne, Gabriel Nunez c/o Doug Green Division of Cellular Immunology, La Jolla Institute for Allergy and Immunology, 10355 Science Center Drive, San Diego, CA 92121, USA Tel: +1 (858) 558 3515 Fax: +1 (858) 558 3526 E-mail: dgreen5240@aol.com Tokyo H Ichijo, S Nagata, Y Tsujimoto, Y Kuchino, S Kumar, D Vaux c/o Hidenori Ichijo Cell Signaling, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan Tel: +81 3 5841 4859 Fax: +81 3 5841 4778 E-mail: cddtokyo@mol.f.u-tokyo.ac.jp Organisation of manuscripts Full papers should be as comprehensive as possible, between 5 and 12 published pages (about 15-40 double spaced A4 pages, excluding tables and figures). The manuscript should be organised as follows: Title page The title page should consist of a title, running title of less than 50 characters, authors, affiliations, and the address/telephone/fax/e-mail of corresponding author; Abstract One single paragraph of no more than 150 words; Keywords and Abbreviations; Introduction; Results; Discussion The discussion may be subdivided by further subheadings or may be combined; Materials and methods This section should contain sufficient detail so that all procedures can be repeated, in conjunction with cited references; References Only articles that have been published or are in press may be included in the references. They should follow the Vancouver format. In the text, they should appear as numbers starting at 1. At the end of the papers they should be listed (double-spaced) in numerical order corresponding to the order of citation in the text. All authors should be quoted. Abbreviations of journal names should conform to the Index Medicus style. The first and last page numbers for each reference should be provided. The following are examples of the reference style: Gottschalk AR, Boise LH, Oltvai ZN, Accavitti MA, Korsmeyer SJ, Quintans J and Thompson CB (1996) The ability of Bcl-XL and Bcl-2 to prevent apoptosis can be differentially regulated. Cell Death Differ. 3: 113-118 Feramisco JR and Welch WJ (1986) Modulation of cellular activities via microinjection into living cells. In Microinjection and organelle transplantation techniques, Celis JE, Graessmann A and Coyter A, eds (London: Academic Press) pp.40-58 File Formats You should stick to high quality JPEG or TIFF files for figures/images, a common word processing package (like Microsoft Word, WordPerfect, Text, or RTF format) for the text, and either embed tables converted into images at the end of your Word document, or as separate files in which ever program you used to generate them. If you submit raw data, this can be done in Excel, or tab/comma delimited format. Tables Each table should be numbered consecutively with an Arabic numeral. Each should have a separate caption or title. Methods not described in the text and abbreviations should be explained at the foot of the Table. Tables should be referred to specifically in the text of the paper. Unlike figures or images, tables may be included in the electronic word processed manuscript file, or supplied as separate electronic files. Illustrations In the manuscript text file: Figures should be in numerical order with Arabic numerals. Each figure should have a title and a detailed legend, as appropriate, listed consecutively on a separate page titled 'Titles and legends to figures'. All explanatory details should be provided in the legend, not the Figure, with the exception of keys which should be embedded within the figure and not in the legend. Figures should be referred to specifically in the text of the paper. Illustration files Supply the actual figures as separate electronic files. Symbols, lettering, and numbering should be clear and large enough to be legible after the figure has been reduced. Please indicate the magnification by a rule. The use of 'three-dimensional' histograms is strongly discouraged when the addition of the third dimension gives no extra information. While illustrations should be referred to specifically in the body of the manuscript text file they must not included as part of that file. Please do not prepare illustrations using Powerpoint software, as that is unsuitable for production. Quality requirements for Figures: Graphs and Line Illustrations in Grayscale- 600dpi Photographs/Halftones (Grayscale)- 300dpi minimum Colour Illustrations in split CMYK- 400dpi Photographs If you would prefer to submit hardcopy photographs or illustrations, please contact the journal office for specific instructions pertaining to quality, fineness of grain, indication of magnification, and marking up multiple copies. Artwork Guidelines Please submit production quality artwork with your initial electronic submission. A JPEG prepared using Adobe Photoshop, Illustrator, Freehand, CorelDraw (or similar industry software) is preferable. Many applications have options to save files as JPEGs, but it is worth noting that sometimes they are only saved at 72dpi, whereas we require 300-600dpi. Following the peer review process, if your paper is accepted for publication, we will not require the artwork to be resubmitted if you have followed the guidelines. Other types of manuscripts Cell Death and Differentiation publishes Reviews, Letters to the Editors, Meeting reports, Book reviews and News and Commentary. Please contact the Editorial Offices for specific information. Style Please avoid using more than three levels of heading. Abbreviations should be kept to a minimum, be clearly defined when used for the first time and listed along with keywords after the abstract. Abbreviations should be typed with no full points. Use italics for emphasis sparingly. Generic names should be used for drugs. Authors should be aware of different drug names and availability in the UK, North America and Australia, and give alternative names of drugs in the text. Footnotes should be avoided. Permissions Authors must obtain permission to reproduce all maps, diagrams, figures and photographs. As a rule it is also necessary to obtain permission for single passages of prose exceeding 250 words, or scattered passages totalling more than 400 words from any one work. Please supply the publisher with full information for all work cited, including author, date published, publisher and page references. Copyright extends to 50 years after the death of the author or 50 years after publication of a scholarly edition, whichever is longer. Copyright Authors will be asked before publication to assign the world copyright of their manuscript to Nature Publishing Group. Therefore, all manuscripts submitted must be accompanied by a signed statement that the article is original, is not under consideration or has not been previously published elsewhere and its content has not been anticipated by any previous publication. Authors will be entitled to publish any part of their paper elsewhere without permission, provided the usual acknowledgements are given. Publication implies that the authors are prepared to supply freely to interested academic researchers any material (DNA, cells, antibody or other) used in the experiments. Nucleic acid and protein sequences should be deposited in appropriate data banks. Proofs Proofs will be supplied once only in the form of page proofs. Submitted manuscripts must be considered as final texts to which no changes should be made at the proof stage apart from correction to printer's errors. Modifications will be charged to the author. Proofs must be returned to the publishers within 48 hours of receipt. If you return proofs even a few days after the date stipulated, it may be too late to include any corrections in the final version of the journal. Page Charges Manuscripts accepted for publication in Cell Death and Differentiation will incur a page charge of ?0 (US $75) per printed page to cover, in part, the cost of publication. Colour on the Web Authors who wish their articles to have FREE colour figures on the web must supply separate files in the following format. These files should be submitted as supplementary information and authors are asked to mention they would like colour figures on the web in their submission letter. For Single Images: Width 500 pixels (authors should select "constrain proportions", or equivalent instructions, to allow the application to set the correct height automatically.) Resolution 72 dpi (dots per inch) - or "Save for Web" if using Photoshop?/SUP> Format JPEG for photographs GIF for line drawings or charts Filenaming Please save image with .jpg or .gif extension to ensure it can be read by all platforms and graphics packages. For Multi-part Images: Width 900 pixels (authors should select "constrain proportions", or equivalent instructions, to allow the application to set the correct height automatically.) Resolution 72 dpi (dots per inch) - or "Save for Web" if using Photoshop?/SUP> Format JPEG for photographs GIF for line drawings or charts Filenaming Please save image with .jpg or .gif extension to ensure it can be read by all platforms and graphics packages. Authors may be asked to pay the full colour fee for figures that are not submitted in the format described above. Offprints Offprint order forms are sent out with the proofs, and must be returned to the publisher. Later orders submitted after the journal is printed are subject to increased reprint prices. Editorial Board Editor-in-Chief Gerry Melino c/o Department of Experimental Medicine University of Rome 'Tor Vergata' Via Montpellier 1 00133 Rome, Italy Tel: +39 06 20427299 Fax: +39 06 20427290 E-mail: cell.death.differ@uniroma2.it Editorial Board John M Abrams Dallas, USA Adriano Aguzzi Zurich, Switzerland Emad S Alnemri Philadelphia, USA Dario C Altieri New Haven, USA Jean C Ameisen Paris, France Eric H Baehrecke College Park, MD, USA Mikhail V Blagosklonny Hawthorne, NY, USA Chris R Bleackley Edmonton, Canada John A Cidlowski Research Triangle Park, USA Gennaro Ciliberto Rome, Italy Gerald M Cohen Leicester, UK Thomas Cotter Cork, Ireland Vincenzo De Laurenzi Rome, Italy Wafik El-Deiry Philadelphia, PA, USA Valerie Fadok Denver, CO, USA Thomas Ferguson St Louis, USA Laszlo Fesus Debrecen, Hungary Alessandro Finazzi-Agro Rome, Italy Douglas R Green San Diego, USA J Marie Hardwick Baltimore, USA Michael Hengartner Zurich, Switzerland H Robert Horvitz Cambridge, USA Hidenori Ichijo Tokyo, Japan John FR Kerr Queensland, Australia Richard A Knight London, UK Richard N Kolesnick New York, USA Stanley J Korsmeyer Boston, USA Peter H Krammer Heidelberg, Germany Guido Kroemer Villejuif, France Yoshiyuki Kuchino Tokyo, Japan Sharad Kumar Adelaide, Australia Stuart A Lipton La Jolla, USA Richard A Lockshin Jamaica, USA Seamus J Martin Dublin, Ireland Jean-Claude Martinou Geneva, Switzerland Masayuki Miura Osaka, Japan Shigekazu Nagata Osaka, Japan Mikihiko Naito Tokyo, Japan Donald W Nicholson Quebec, Canada Pierluigi Nicotera Leicester, UK Gabriel Nunez Ann Arbor, USA Moshe Oren Rehovot, Israel Sten Orrenius Stockholm, Sweden Barbara A Osborne Amherst, USA Marcus E Peter Chicago, USA Mauro Piacentini Rome, Italy Martin C Raff London, UK John C Reed La Jolla, USA Antony Rosen Baltimore, USA Sophie Roy Quebec, Canada Guy Salvesen La Jolla, USA Andreas Strasser Melbourne, Australia Carol J Thiele Bethesda, USA Craig B Thompson Philadelphia, USA Jonathan L Tilly Boston, USA Jurg Tschopp Lausanne, Switzerland Yoshihide Tsujimoto Osaka, Japan David Vaux Melbourne, Australia Karen Vousden Frederick, USA Jean YJ Wang La Jolla, USA Xiadong Wang Dallas, TX, USA Junying Yuan Boston, USA